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| 1 | Outcomes of Medicare beneficiaries hospitalised with transient ischaemic attack and stratification using the ABCD^(2) score显示文摘Background Long-term outcomes for Medicare beneficiaries hospitalised with transient ischaemic attack(TIA)and role of ABCD^(2) score in identifying high-risk individuals are not studied.Methods We identified 40825 Medicare beneficiaries hospitalised from 2011 to 2014 for a TIA to a Get With The Guidelines(GWTG)-Stroke hospital and classified them using ABCD^(2)s of mortality and rehospitalisation(all-cause,ischaemic stroke,haemorrhagic stroke,myocardial infarction,and gastrointestinal and intracranial haemorrhage)for high-risk versus low-risk groups adjusted for patient and hospital characteristics.Results Of the 40825 patients,35118(86%)were high risk(ABCD^(2)≥4)and 5707(14%)were low risk(ABCD^(2)=0-3).Overall rate of mortality during 1-year follow-up after hospital discharge for the index TIA was 11.7%,44.3% were rehospitalised for any reason and 3.6%were readmitted due to stroke.Patients with ABCD^(2) score≥4 had higher mortality at 1 year than not(adjusted HR 1.18,95%CI 1.07 to 1.30).Adjusted risks for ischaemic stroke,all-cause readmission and mortality/all-cause readmission at 1 year were also significantly higher for patients with ABCD^(2) score≥4 vs 0-3.In contrast,haemorrhagic stroke,myocardial infarction,gastrointestinal bleeding and intracranial haemorrhage risk were not significantly different by ABCD^(2) score.Conclusions This study validates the use of ABCD^(2) score for long-term risk assessment after TIA in patients aged 65 years and older.Attentive efforts for community-based follow-up care after TIA are needed for ongoing prevention in Medicare beneficiaries who were hospitalised for TIA. | Shreyansh Shah Li Liang Durgesh Bhandary Saga Johansson Eric E Smith Deepak L Bhatt Gregg C Fonarow Naeem D Khan Eric Peterson Janet Prvu Bettger | 2021 | Stroke & Vascular Neurology2021，6，2： | 3 |
| 2 | Prevalence and clinical characteristics associated with left atrial thrombus detection: Apixaban显示文摘BACKGROUND The prevalence of left atrial appendage(LAA) thrombus detection by transesophageal echocardiogram(TEE) in patients with non-valvular atrial fibrillation(AF) anticoagulated with apixaban is not well defined and identification of additional risk factors may help guide the selection process for pre-procedural TEE. The purpose of our study was to retrospectively analyze the prevalence of LAA thrombus detection by TEE in patients continuously anticoagulated with apixaban for ≥ 4 wk and evaluate for any cardiac risk factors or echocardiographic characteristics which may serve as predictors of thrombus formation.AIM To retrospectively analyze the prevalence of LAA thrombus detection by TEE in patients continuously anticoagulated with apixaban.METHODS Clinical and echocardiographic data for 820 consecutive patients with AF undergoing TEE at Augusta University Medical Center over a four-year period were retrospectively analyzed. All patients(apixaban: 226) with non-valvular AF and documented compliance with apixaban for ≥ 4 wk prior to index TEE were included.RESULTS Following ≥ 4 wk of continuous anticoagulation with apixaban, the prevalence ofLAA thrombus and LAA thrombus/dense spontaneous echocardiographic contrast was 3.1% and 6.6%, respectively. Persistent AF, left ventricular ejection fraction < 30%, severe LA dilation, and reduced LAA velocity were associated with thrombus formation. Following multivariate logistic regression, persistent AF(OR: 7.427; 95%CI: 1.02 to 53.92; P = 0.0474), and reduced LAA velocity(OR:1.086; 95%CI: 1.010 to 1.187; P = 0.0489) were identified as independent predictors of LAA thrombus. No Thrombi were detected in patients with a CHA2 DS2-VASc score ≤ 1.CONCLUSION Among patients with non-valvular AF and ≥ 4 wk of anticoagulation with apixaban, the prevalence of LAA thrombus detected by TEE was 3.1%. This suggests that continuous therapy with apixaban does not completely eliminate the risk of LAA thrombus and that TEE prior to cardioversion or catheter ablation may be of benefit in patients with multiple risk factors. | Hoyle L Whiteside Arun Nagabandi Kristen Brown Deepak N Ayyala Gyanendra K Sharma | 2019 | World Journal of Cardiology2019，11，2： | 2 |
| 3 | Tuning the bandgap of ZnO by substitution with Mn2+ , Co2+ and Ni2+显示文摘 | VENKATAPRASAD B S DEEPAK F L | 2005 | Solid State Communications2005，135，： | 1 |
| 4 | Normalizing gly- cosphingolipids restores function in CD4T cells from lupus pa- tients显示文摘 | MCDONALD G DEEPAK S MIGUEL L | 2014 | Clin Invest2014，124，2： | 1 |
| 5 | Pdcatalyzed efficient cross couplings of 3-iodochromones with triaryl bismuths as substoichiometric multicoupling organometallic nucleophiles显示文摘 | Rao Maddali L N Venkatesh V Jadhav Deepak N | 2009 | Synlett2009，16，： | 1 |
| 6 | Aircraft structural morphing using tendon-actuated compliant cellular trusses显示文摘 | Deepak S R George A L Mary F | 2005 | Journal of Aircraft2005，42，6： | 1 |
| 7 | 显示文摘 | Rao C N R Deepak F L Gundiah G | 2003 | Prog Solid State Chem2003，31，12： | 1 |
| 8 | Boron nitride nanotubes and nanowires 显示文摘 | Deepak F L Vinod C P Mukhopadhyay K | 2002 | Chemical Physics Lett2002，353，： | 1 |
| 9 | 显示文摘 | Rao C N R Deepak F L Gautam G | 2003 | Prog Solid State Chem2003，31，1： | 1 |
| 10 | Boron nitride nanotubes and nanowires显示文摘 | DEEPAK F L VINOD C P MUKHOPADHYAY K | 2002 | Chem Phys Lett2002，353，： | 1 |
| 11 | Synthetic strategies for Y-junction carbon nanotubes显示文摘 | DEEPAK L GOWINDARAJ A RAO C N R | 2001 | Chem Phys Letts2001，345，： | 1 |
| 12 | Pd-catalyzed synthesis of α-aryl ketones through couplings of a-arylacetyl chlorides with triarylbismuths as multi-coupling nucleophiles显示文摘 | Maddali L N Rao Somnath Giri Deepak L J | | 0，，43： | 1 |
| 13 | Tuning the bandgap of ZnO by substitution with Mn2+,Co2+ and Ni2+显示文摘 | Deepak F L | 2005 | Solid State Communications2005，135，： | 1 |
| 14 | Inorganic nanowires显示文摘 | RAO C N R DEEPAK F L GUNDIAH G | 2003 | Progress in Solid State Chem2003，31，： | 1 |
| 15 | Carbon- assisted synthesis of nanowires and related nanostruc- tures of MgO显示文摘 | Kalyanikutty K P Deepak F L Edem C | 2005 | Materials Research Bulletin2005，40，5： | 1 |
| 16 | Uncertainty assess- ment of hypersonic aerothermodynamics prediction capability 显示文摘 | DEEPAK BOSE D BROWN J L | 2013 | Journal of Spacecraft and Rockets2013，50，1： | 1 |
| 17 | Local epileptogenic networks in tuberous sclerosis complex : a case review 显示文摘 | Deepak Madhavan Howard L Chad Carlson | 2007 | Epilepsy and Behavior2007，11，1： | 1 |
| 18 | Inorganic nanowires显示文摘 | RAO C N R DEEPAK F L GUNDIAH G | 2003 | Prog Solid State Ch2003，31，12： | 1 |
| 19 | The relative efficacy and safety of clopidogrel in women andmen--A sex specific collaborative meta-analysis 显示文摘 | Jefrey S B Deepak L B Christopher P C | 2009 | J Am ColI Cardio12009，54，： | 1 |
| 20 | Clinical out- comes of patients with diabetic nephropathy randomied to clopi- dogrel plus aspirin versus aspirin alone ( A post hoc analysis of the clopidogrel for high atherothrombotic risk and ischemic stabi- lization, management, and avoidance Trial)显示文摘 | DASGUPTA A STEVEN R DEEPAK L | 2009 | Am J Cardiol2009，103，10： | 1 |
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