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| 1 | FOLFIRI联合西妥昔单抗或贝伐珠单抗治疗晚期结直肠癌:随机临床试验FIRE-3的最终生存及符合方案分析显示文摘背景:在FIRE-3研究中,与贝伐珠单抗+FOLFIRI相比,西妥昔单抗+FOLFIRI可提高KRAS野生型转移性结直肠癌(mCRC)的总生存率,但是未发现相应的无进展生存获益。本研究目的在于分析RAS野生型结直肠癌接受一线FOLFIRI治疗的可评价疗效患者中,与贝伐珠单抗相比,西妥昔单抗是否可改善治疗反应和生存情况,同时分析原发肿瘤部位对预后的影响。方法:意向治疗人群包括593例KRAS第2外显子野生型mCRC患者。进一步检测确认400名患者为全RAS野生型肠癌,其中352名(88%)患者接受了至少3个周期的治疗和至少1次基线后的影像检查以评估疗效,并纳入符合方案的患者(西妥昔单抗组169名,贝伐珠单抗组183名)。 | 何婉 HEINEMANN V VON WEIKERSTHAL L F DECKER T | 2021 | 结直肠肛门外科2021，27，1： | 11 |
| 2 | Experimental evaluation of ground-based microwave radiomewtric sensing of atmospheric temperature and water vapor profiles显示文摘 | Decker M T E R Westwater F O Guiraud | 1978 | J Appl Meteor1978，17，： | 2 |
| 3 | An automatic profiler of the temperature, wind, ancl humidity in the tropo sphere显示文摘 | Hogg D C M T Decker F O Guiraud | 1983 | J Appl Meteor1983，22，： | 1 |
| 4 | Evolution of the GPGP/TAEMS domain-independent coordination framework显示文摘 | LESSER V DECKER K WAGNER T | 2004 | Autonomous Agents and Multi-agent Systems2004，9，1： | 1 |
| 5 | A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity显示文摘 | Lohmann-Matthes ML | 1988 | J Immunol Methods1988，115，1： | 1 |
| 6 | Surgical techniques显示文摘 | Lerut T Cooserrmns W Decker G | 2005 | J Surg Oneol2005，92，3： | 1 |
| 7 | UV - radiation curing of waterbased urethane acrylate coating 显示文摘 | Masson F Decker C Jaworek R T | 2000 | J Progress in Organic Coating2000，，39： | 1 |
| 8 | Stereotactic vacuum-assisted berast biopsies in 500 women with microcalcifications :radiologieal and pathological correlations显示文摘 | Kettritz U Morack G Decker T | 2005 | Eur J Radiol2005，55，2： | 1 |
| 9 | Structure of high-pressure KNO3 -Ⅳ 显示文摘 | Worlton T G Decker D L Jorgensen J D | 1986 | Physica B + C1986，136，13： | 1 |
| 10 | Antioxidant capacities of a- tocopherol, trolox, ascorbic acid, and aseorbyl palmitate in riboflavin photosensitized oil-in-water emulsions 显示文摘 | Kim T S Decker E A Lee J | 2012 | Food Chemistry2012，133，1： | 1 |
| 11 | JAK-STAT signaling: fi'om interferons to cytokines 显示文摘 | Schindler C Levy DE Decker T | 2007 | J Biol Chem2007，282，20： | 1 |
| 12 | JAK-STAT signaling: from interferons to cytokines 显示文摘 | Schindler C Levy DE Decker T | 2007 | J Biol Chem2007，282，20： | 1 |
| 13 | Increased number of regulatory T cells (T-regs) in the peripheral blood of patients with Her-2/neu-positive earlybreast cancer显示文摘 | Decker T Fischer G Bilcke W | 2012 | J Cancer Res Clin Oncol2012，138，11： | 1 |
| 14 | Stereotactic vacuum-assisted breast biopsies in 500women with mierocalcifications:radiological and pathological correlations显示文摘 | Kettritz U Morack G Decker T | 2005 | Eur J Radiol2005，55，2： | 1 |
| 15 | Jaks, stats and the immune system 显示文摘 | Decker T | 1997 | Immunobiology1997，198，： | 1 |
| 16 | Destabilization of cohesive intertidal sediments by infauna 显示文摘 | de Deckere E M G T Tolhurst T J de Brouwer J F C | 2001 | Estuarine Coastal and Shelf Science2001，53，： | 1 |
| 17 | Tarantula hemocyanin shows phenoloxidase activity显示文摘 | Decker H Rimke T | 1998 | J Biol Chem1998，，25： | 1 |
| 18 | Photoinitiated cat- ionic polymerization of epoxidest显示文摘 | Decker C Nguyen T Viet T | 2001 | Polym In2001，50，9： | 1 |
| 19 | Influence of environmental stresses on stability of O/W emulsions containing droplets stabilized by multilayered membranes produced by a layer-by-layer electrostatic deposition technique显示文摘 | Aoki T Decker E A | 2005 | Food Hydrocolloids2005，19，： | 1 |
| 20 | Novel paradigms in vaccine development: from small pox eradication to therapeutic vaccines 显示文摘 | von Gabain A Nagy E Decker T | 2008 | Biol Chem2008，389，5： | 1 |
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