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		题名	作者	年代	出处	被引量
	1	Role of endoscopic ultrasound in the screening and follow-up of high-risk individuals for familial pancreatic cancer显示文摘Managing familial pancreatic cancer(FPC)is challenging for gastroenterologists,surgeons and oncologists.High-risk individuals(HRI)for pancreatic cancer(PC)(FPC or with germline mutations)are a heterogeneous group of subjects with a theoretical lifetime cumulative risk of PC over 5%.Screening is mainly based on annual magnetic resonance imaging(MRI)and endoscopic ultrasound(EUS).The goal of screening is to identify early-stage operable cancers or high-risk precancerous lesions(pancreatic intraepithelial neoplasia or intraductal papillary mucinous neoplasms with high-grade dysplasia).In the literature,target lesions are identified in 2%-5%of HRI who undergo screening.EUS appears to provide better identification of small solid lesions(0%-46%of HRI)and chronicpancreatitis-like parenchymal changes(14%-77%of HRI),while MRI is probably the best modality to identify small cystic lesions(13%-49%of HRI).There are no specific studies in HRI on the use of contrast-enhanced harmonic EUS.EUS can also be used to obtain tissue samples.Nevertheless,there is still limited evidence on the accuracy of imaging procedures used for screening or agreement on which patients to treat.The cost-effectiveness of screening is also unclear.Certain new EUS-related techniques,such as searching for DNA abnormalities or protein markers in pancreatic fluid,appear to be promising.	Diane Lorenzo Vinciane Rebours Frédérique Maire Maxime Palazzo Jean-Michel Gonzalez Marie-Pierre Vullierme Alain Aubert Pascal Hammel Philippe Lévy Louis de Mestier	2019	World Journal of Gastroenterology2019，25，34：	2
	2	Laparoscopic thermal ablation of splenic metastasis initial experience and present aspects 显示文摘	Lardiere-Deguelte S de Mestier L Amroun KL	2013	J Visceral Surg2013，150，5：	1
	3	MEK in cancer and cancer therapy显示文摘	Neuzillet C Tijeras-Raballand A de Mestier L	2014	Pharmacol Ther2014，141，2：	1
	4	News in management of colorectal cancer at JFHOD 2012 meeting 显示文摘	Volet J de Mestier L Ehrhard F	2012	Bull Cancer2012，99，6：	1
	5	MEK in cancer and cancer therapy显示文摘	NEUZILLET C TIJERAS-RABALLAND A DE MESTIER L etal	2014	Pharmacol Ther2014，141，2：	1
	6	MEK in cancerand cancer therapy 显示文摘	Neuzillet C Tijeras-Raballand A de Mestier L	2014	Pharmacol Ther2014，14，2：	1

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