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| 1 | Phased,chromosome-scale genome assemblies of tetraploid potato reveal a complex genome,transcriptome,and predicted proteome landscape underpinning genetic diversity显示文摘Cultivated potato is a clonally propagated autotetraploid species with a highly heterogeneous genome.Phased assemblies of six cultivars including two chromosome-scale phased genome assemblies revealed extensive allelic diversity,including altered coding and transcript sequences,preferential allele expression,and structural variation that collectively result in a highly complex transcriptome and predicted proteome,which are distributed across the homologous chromosomes.Wild species contribute to the extensive allelic diversity in tetraploid cultivars,demonstrating ancestral introgressions predating modern breeding efforts.As a clonally propagated autotetraploid that undergoes limited meiosis,dysfunctional and deleterious alleles are not purged in tetraploid potato.Nearly a quarter of the loci bore mutations are predicted to have a high negative impact on protein function,complicating breeder’s efforts to reduce genetic load.The StCDF1 locus controls maturity,and analysis of six tetraploid genomes revealed that 12 allelic variants of StCDF1 are correlated with maturity in a dosage-dependent manner.Knowledge of the complexity of the tetraploid potato genome with its rampant structural variation and embedded deleterious and dysfunctional alleles will be key not only to implementing precision breeding of tetraploid cultivars but also to the construction of homozygous,diploid potato germplasm containing favorable alleles to capitalize on heterosis in F1 hybrids. | Genevieve Hoopes Xiaoxi Meng John P.Hamilton Sai Reddy Achakkagari Fernanda de Alves Freitas Guesdes Marie E.Bolger Joseph J.Coombs Danny Esselink Natalie R.Kaiser Linda Kodde Maria Kyriakidou Brian Lavrijssen Natascha van Lieshout Rachel Shereda Heather K.Tuttle Brieanne Vaillancourt Joshua C.Wood Jan Mde Boer Nolan Bornowski Peter Bourke David Douches Herman Jvan Eck Dave Ellis Max J.Feldman Kyle M.Gardner Johannes C.P.Hopman Jiming Jiang Walter S.De Jong Joseph C.Kuhl Richard G.Novy Stan Oome Vidyasagar Sathuvalli Ek Han Tan Remco A.Ursum M.Isabel Vales Kelly Vining Richard G.F.Visser Jack Vossen G.Craig Yencho Noelle L.Anglin Christian W.B.Bachem Jeffrey B.Endelman Laura M.Shannon Martina V.Stromvik Helen H.Tai Bjorn Usadel C.Robin Buell Richard Finkers | 2022 | Molecular Plant2022，15，3： | 4 |
| 2 | Generalization of the phase-screen approximation for the scattering of acoustic waves显示文摘 | DE HOOP M V LE ROUSSEAU J H WU R S | 2000 | Wave Motion2000，，31： | 1 |
| 3 | Automatic segmentation of pulmonary segments from volumetric chest CT scans 显示文摘 | Van Rikxoort E M de Hoop B van de Vorst S ProkopM van Ginneken B | 2009 | Medical Imaging IEEE Transactions on2009，28，4： | 1 |
| 4 | Generalization of the phase-screen approximation for the scattering of acoustic waves显示文摘 | DE HOOP M LE R J WU R S | 2000 | Wave Motion2000，31，： | 1 |
| 5 | A modification of Cagniard's method for solving seismic pulse problem显示文摘 | De Hoop A T | 1960 | Applied Science Research1960，8，： | 1 |
| 6 | Biological conversion of anglesite (PbSO4) and lead waste from spent car batteries to galena (Pb5) 显示文摘 | Weijma J de Hoop K Bosma W | 2002 | Biotechnol Progress2002，18，4： | 1 |
| 7 | Generalization of the phase-screen approximation for the scattering of acoustic waves显示文摘 | De Hoop M V Le Rousseau J H Wu R S | 2000 | Wave Motion2000，31，： | 1 |
| 8 | Focusing in dip and AVA compensation on scattering-angle/azimuth common image gathers显示文摘 | BRANDSBERG-DAHL S DE HOOP M V Ursin B | 2003 | Geophysics2003，68，2： | 1 |
| 9 | CT-quantified emphysema in male heavy smokers: association with lung function decline 显示文摘 | Mohamed HF de Hoop B Zanen P | 2011 | Thorax2011，66，9： | 1 |
| 10 | A novel application of time-reversed acoustics: Salt-dome flank imaging using walkaway VSP surveys显示文摘 | Willis M E Lu R R Campman X Toks M N Zhang Y and de Hoop M V | 2006 | Geophysics2006，71，2： | 1 |
| 11 | Over expression of alcohol oxidase in Pich ia pastoris显示文摘 | De Hoop MJ CreggJ Keizer-Gunnink I | 1991 | FEBS Lett1991，291，2： | 1 |
| 12 | Lung nodule volumetry= segmentation algorithms within the same software package cannot be used interchangeably显示文摘 | Ashraf H de Hoop B Shaker B | 2010 | Eur Radiol2010，20，8： | 1 |
| 13 | Automatic Segmentation of Pulmonary Segments From Volumetric Chest CT Scans显示文摘 | Van Rikxoort E M de Hoop B van de Vorst S | 2009 | IEEE Transactions on Medical Imaging2009，28，4： | 1 |
| 14 | Surface- Wave Array Tomography in SE Tibet from a Mbient Seismic Noise and Two-Station Analysis: I: Phase Velocity Maps 显示文摘 | Yao H J Van Der Hilst R'D De Hoop M V | 2006 | Geophysical Journal International2006，166，2： | 1 |
| 15 | Double-bllnd,fight/left comparison of calcipotriol and betamethasone valerate in treatment of psoriasis vulgaris显示文摘 | Kragballe K Gjertsen BT De Hoop D | 1991 | Lancet1991，337，8735： | 1 |
| 16 | Basic parametric study on corrugated web girders with cut outs显示文摘 | Romeijn A Sarkhosh R Huigert de Hoop | 2009 | Journal of Constructional Steel Research2009，65，2： | 1 |
| 17 | Au- tomatic lung segmentation from thoracic CT scans using a hybrid ap- proach with error detection 显示文摘 | Van RIKXOORT E M De HOOP B VIERGEVER M A | 2009 | Medical Physics2009，36，7： | 1 |
| 18 | Approximate dispersion relations for qP-qSV-waves in transversely isotropic media显示文摘 | Schoenberg M A de Hoop M V | 2000 | Geophysics2000，65，3： | 1 |
| 19 | Modeling and imaging with the scalar generalized-screen algorithms in isotropic media显示文摘 | Le Rousseau J H de Hoop M V | 2001 | Geophysics2001，66，5： | 1 |
| 20 | The moving-load problem in soil dynamics-the vertical displacement approximation 显示文摘 | DE HOOP A T | 2002 | Wave Motion2002，36，4： | 1 |
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