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| 1 | 针对Beta冠状病毒的疫苗设计显示文摘新型冠状病毒是Beta-CoV谱系B的成员,与严重急性呼吸系统综合征冠状病毒(SARS-CoV)基因组序列有75%至80%同源性。疫苗是控制正在流行的COVID-19和既往MERS/SARS等冠状病毒感染的有效措施。刺突受体结合结构域(RBD)是冠状病毒疫苗的理想靶点,但RBD有限的免疫原性限制了针对该结构域的疫苗研发。 | 安华英(编译) Dai L Zheng T Xu K | 2020 | 中华医学杂志2020，100，32： | 27 |
| 2 | Mutation analysis of autosomal dominant polycystic kidney disease genes in Han Chinese显示文摘 | Zhang S Mei C Zhang D Dai B Tang B Sun T Zhao H Zhou Y Li L Wu Y Wang W Shen X Song J | 2005 | 第二军医大学学报2005，26，8： | 6 |
| 3 | A multiclass station with Markovian feedbback in heavy traffic显示文摘 | Dai J G Kurtz T G | 1995 | Math Oper Res1995，20，： | 3 |
| 4 | Tissue expression and developmental regulation of chicken cathelicidin antimicrobial peptides显示文摘Cathelicidins are a major family of antimicrobial peptides present in vertebrate animals with potent microbicidal and immunomodulatory activities. Four cathelicidins, namely fowlicidins 1 to 3 and cathelicidin B1, have been identified in chickens. As a first step to understand their role in early innate host defense of chickens, we examined the tissue and developmental expression patterns of all four cathelicidins. Real-time PCR revealed an abundant expression of four cathelicidins throughout the gastrointestinal, respiratory, and urogenital tracts as well as in all primary and secondary immune organs of chickens. Fowlicidins 1 to 3 exhibited a similar tissue expression pattern with the highest expression in the bone marrow and lung, while cathelicidin B1 was synthesized most abundantly in the bursa of Fabricius. Additionally, a tissue-specific regulatory pattern was evident for all four cathelicidins during the first 28 days after hatching. The expression of fowlicidins 1 to 3 showed an age-dependent increase both in the cecal tonsil and lung, whereas all four cathelicidins were peaked in the bursa on day 4 after hatching, with a gradual decline by day 28. An abrupt augmentation in the expression of fowlicidins 1 to 3 was also observed in the cecum on day 28, while the highest expression of cathelicidin B1 was seen in both the lung and cecal tonsil on day 14. Collectively, the presence of cathelicidins in a broad range of tissues and their largely enhanced expression during development are suggestive of their potential important role in early host defense and disease resistance of chickens. | Mallika Achanta Lakshmi T Sunkara Gan Dai Yugendar R Bommineni Weiyu Jiang Guolong Zhang | 2012 | Journal of Animal Science and Biotechnology2012，3，2： | 3 |
| 5 | NANOTUBES AS NANOPROBES IN SCANNING PROBE MICROSCOPY显示文摘 | Dai H Hafner J H Rinzler A G Colbert D T Smalley R E | | 0，，： | 2 |
| 6 | River basin network model for integrated water quantity/quality management 显示文摘 | Dai T Labadie J W | 2001 | Journal of Water Resources Planning and Management2001，127，5： | 2 |
| 7 | iSPITM-the improved source parameter imaging method 显示文摘 | Smith R S Thurston J B Dai T | 1998 | Geophysical Prospecting1998，46，： | 1 |
| 8 | Targeting tumours by adoptive transfer of immune cells显示文摘 | Macary P A Too C T Dai X | 2006 | Clin Exp Pharmacol Physiol2006，33，56： | 1 |
| 9 | Moment Resistance of Steel Ⅰ-Beam to CFT Column Connection显示文摘 | Chiew S P Lie S T Dai C W | 2001 | Journal of Structural Engineering2001，，： | 1 |
| 10 | SelectiVe inhibition of NF-κB attenuates the severity of cerulein-Induced acute pancreatitis显示文摘 | Ethridge R T Hashimoto K Dai H | 2002 | J Am Coll Surg2002，195，4： | 1 |
| 11 | Gene expression profiling predicts clinical outcome of breast cancer 显示文摘 | van't Veer L J Dai H van de Vijver M J | 2002 | Nature2002，415，6871： | 1 |
| 12 | Rverine input and air-sea C02 ex-changes near the Changjiang (Yangtze River) Estuary : Status quo andimplication on possible future changes in metabolic status显示文摘 | Chen C T A Zhai W D Dai M H | 2008 | ContientalShelf Research2008，28，： | 1 |
| 13 | Detection of mutations in the DNA polymerase delta gene of human sporadic colorectal cancers and colon cancer cell lines 显示文摘 | Flohr T Dai JC Buttner J | 1999 | Int J Cancer1999，80，6： | 1 |
| 14 | Photodynamic therapy for lo- calized infections-state of the art 显示文摘 | Dai T Huang YY Hamblin MR | 2009 | Photodiagrwsis Photodyn Ther2009，6，34： | 1 |
| 15 | The nuts and bolts of low-level laser (light) therapy显示文摘 | Chung H Dai T Sharma SK | 2012 | Ann B iomed Eng2012，40，2： | 1 |
| 16 | Decreased plasma nesfatin-1 levels in patients with acute myocardial infarction 显示文摘 | Dai H Li X He T | 2013 | Peptides2013，46，： | 1 |
| 17 | Simultaneous codeword optimiza- tion (SimCO) for dictionary update and learning 显示文摘 | Dai W Xu T Wang W | 2012 | IEEE Transactions on Signal Processing2012，60，12： | 1 |
| 18 | IrrE, a global regulator of extreme radiation resistance inDeinococcus radiodurans, enhances salt tolerance in Escherichia coli and Brassica napus显示文摘 | Pan J Wang J Zhou Z Yan Y Zhang W Lu W Ping S Dai Q Yuan M Feng B Hou X Zhang Y Ma R Liu T Feng L Wang L Chen M Lin M | 2009 | PloS One2009，4，2： | 1 |
| 19 | Damage and failure analysis of brittle materials by acoustic emission 显示文摘 | Dai S T Labuz J F | 2005 | Rock Mechanics and Rock Engineering2005，38，1： | 1 |
| 20 | The study of the coexistence of Hashimo- to~ thyroiditis with papillary thyroid carcinoma显示文摘 | Zhang Y Dai J Wu T | 2014 | J Cancer Res Clin Onco2014，140，6： | 1 |
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