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1High-intensity focused ultrasound ablation:An effective bridging therapy for hepatocellular carcinoma patients显示文摘AIM:To analyze whether high-intensity focused ultrasound(HIFU) ablation is an effective bridging therapy for patients with hepatocellular carcinoma(HCC).METHODS:From January 2007 to December 2010,49 consecutive HCC patients were listed for liver transplantation(UCSF criteria).The median waiting time for transplantation was 9.5 mo.Twenty-nine patients received transarterial chemoembolization(TACE) as a bringing therapy and 16 patients received no treatment before transplantation.Five patients received HIFU ablation as a bridging therapy.Another five patients with the same tumor staging(within the UCSF criteria) who received HIFU ablation but not on the transplant list were included for comparison.Patients were comparable in terms of Child-Pugh and model for end-stage liver disease scores,tumor size and number,and cause of cirrhosis.RESULTS:The HIFU group and TACE group showed no difference in terms of tumor size and tumor number.One patient in the HIFU group and no patient in the TACE group had gross ascites.The median hospital stay was 1 d(range,1-21 d) in the TACE group and two days(range,1-9 d) in the HIFU group(P < 0.000).No HIFU-related complication occurred.In the HIFU group,nine patients(90%) had complete response and one patient(10%) had partial response to the treatment.In the TACE group,only one patient(3%) had response to the treatment while 14 patients(48%) had stable disease and 14 patients(48%) had progressive disease(P = 0.00).Seven patients in the TACE group and no patient in the HIFU group dropped out from the transplant waiting list(P = 0.559).CONCLUSION:HIFU ablation is safe and effective in the treatment of HCC for patients with advanced cirrhosis.It may reduce the drop-out rate of liver transplant candidate.Tan To Cheung Sheung Tat Fan See Ching Chan Kenneth SH Chok Ferdinand SK Chu Caroline R Jenkins Regina CL Lo James YY Fung Albert CY Chan William W Sharr Simon HY Tsang Wing Chiu Dai Ronnie TP Poon Chung Mau Lo 2013World Journal of Gastroenterology2013,19,20:23
2Nanobelts of semiconducting oxides显示文摘PAN Z W DAI Z R WANG Z L 2001Science2001,291,5510:1
3IrrE, a global regulator of extreme radiation resistance inDeinococcus radiodurans, enhances salt tolerance in Escherichia coli and Brassica napus显示文摘Pan J Wang J Zhou Z Yan Y Zhang W Lu W Ping S Dai Q Yuan M Feng B Hou X Zhang Y Ma R Liu T Feng L Wang L Chen M Lin M 2009PloS One2009,4,2:1
4Nanobelts of semiconduct- ing ox-ides显示文摘Pan Z W Dai Z R Wang Z L 2001Science2001,291,:1
5Synthesis of Bi6Mo2015sub-microwires via a molten salt method and enhancing thephotocatalytic reduction of CO2 into solar fuel through tuning the surface oxide vacancies by simple post-heating treatment显示文摘Li P Zhou Y Tu W Wang R Zhang C Liu Q Li H Li Z Dai H Wang J Yan S Zou Z 2013CrystEngComm2013,15,46:1
6Expression pattern genomic struc- ture, and promoter analysis of the gene encoding stilbene synthase from Chinese wild Vitis pseudoreticulata显示文摘XU W R YU Y H ZHOU Q DING J H DAI L M XIE X Q XU Y ZHANG C H WANG Y J 2011Journal of Experimen- tal Botany2011,62,8:1
7Anal Chim Acta显示文摘Jing T Xia H Guan Q Lu W H Dai Q Niu J W Lim J M Hao Q L Lee Y Zhou Y K Mei S R 2011692:732011,692,:1
8Nanobelts of semi- conducting oxides显示文摘Pan Z W Dai Z R Wang Z L 2001Science2001,291,:1
9显示文摘Pan Z W Dai Z R Wang Z L 2001Science2001,291,:1
10Effect of fructose-1,6-diphosphate on mortality in patients with acute myocardial infarction显示文摘Wang S Y Dai R H Feng W H 0,,:1
11New green catalytic manufacture of glutaric acid from the oxidation of cyclopentane-1, 2-dlol with aqueous hydrogen peroxide 显示文摘Chen H Dai W L Gao R H 2007Applied Catalysis A: General2007,328,2:1
12Molten gallium as a catalyst for the large-scale growth of highly aligned silica nanowires显示文摘PAN Z W DAI Z R MA C 2002J Am Chem Soc2002,124,8:1
13Numerical simulation of pulsed eddy current nondestructive testing phenomena显示文摘Dai X W Ludwig R Palanisamy R 1990IEEE Transactions on Magnetics1990,26,6:1
14Synthesis, character- ization and catalytic application of mesoporous W-MCM-48 for the selective oxidation of cyclopentene to glutaralde- hyde显示文摘Yang X L Dai W L Gao R H 2005J Mol Catal A: Chem2005,241,12:1
15A finite difference method for studying thermal deformation in a double-layed thin film exposed to ultrashort pulsed lasers 显示文摘WANG H J DAI W MELNIK R 2006Int J Thermal Sci2006,45,11:1
16Numerical and analytical modeling of pulsed eddy currents in a conducting half spac6 显示文摘Ludwig R Dai X W 1990IEEE Transctions on Magnetics1990,26,1:1
17Structure-activity relationships for inhibition of human 5alpha-reductases by polyphenols显示文摘Hiipakka R A Zhang H Z Dai W 2002Biochem Pharmacol2002,63,:1
18Nanobelts of semiconducting oxides显示文摘Pan Z W Dai Z R Wang Z L 2001Science2001,291,5510:1
19N-N interactions in the extended ehiral SU(3) quark model显示文摘DAI L R ZHANG Z Y YU Y W 2003Nucl Phys2003,727,:1
20AMAZING : A Sentiment Mining and Retrieval System 显示文摘Miao Q L Li Q D Dai R W 2009Expert Systems with Applications2009,36,3:1
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