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    题名 作者 年代 出处 被引量
1Testing Potential Effect of Environmental Endocrine Disruptors in Cow Milk on Reproductive Index in Female Rats显示文摘Objective To study the effect of endocrine disruptor chemicals in cow milk on female reproductive system. Methods A two-generation reproduction was conducted according to U. S. FDA standard. Milk was fed in special bottle to Wistar rats of both sexes through two successive generations (F0 and F1) in the milk group while artificial milk was fed to rats in the control group. Twenty-four rats of each sex were mated in each group. Measurements were made according to this guideline. Results Reproductive parameters in the milk group such as fertility index, gestation index, weights of uterus and ovary, days of vaginal opening, estrous cycles, histological morphological changes were comparable to those in the control group. However, the means of body weight had some differences. The body weight gains increased significantly in the milk-treated group in F1 and F2 generation compared with those in the control group. The concentration of insulin-like growth factor-1 (IGF-1) in blood in the milk group was comparable to that in the control group, but the standard deviation changed greatly in the milk-treated rats. Conclusion Endocrine disruptor chemicals in milk have no severe effects on the female reproductive system.XIANG-MING LI DAVAASAMBUU GANMAA LI-QIANG QIN AKIO SATO 2005Biomedical and Environmental Sciences2005,18,5:2
2牛奶中雌激素类化合物对前列腺和睾丸的影响显示文摘目的 :研究牛奶中雌激素样物质对男性生殖系统的影响。 方法 :利用世界五大洲肿瘤发病数据库和联合国粮农组织 (FAO)数据库 ,对 42个国家 (地区 )前列腺癌和睾丸癌发病率 ( 1988~ 1992 )与相应的食物消费量资料 ( 1961~ 1990 )进行相关分析 ;根据美国食品药品管理局 (FDA)标准 ,选用Wistar大鼠 ,进行两代繁殖实验 ,主要研究牛奶中雌激素化合物对生殖器官的影响。 结果 :在所分析的食物中 ,前列腺癌与牛奶消费量的关系最密切(r =0 .711) ,其次是肉类与咖啡 ;奶酪与 2 0~ 3 9岁的睾丸癌标化发病率关系最密切 (r =0 .80 4) ,其次是动物性脂肪和牛奶 ;动物实验研究发现 ,大鼠经长期、大量地饮用牛奶后 ,未发现生殖器官明显减轻的现象。 结论李湘鸣 Davaasambuu Ganmaa 秦立强 刘秀梵 Akio Sato 2003中华男科学杂志2003,9,3:1
3A two-generation reproduction study to assess the effects of cows' milk on reproductive development in male and female rats 显示文摘Davaasambuu Ganmaa Li-Qiang Qin Pei-Yu Wang 2004Fertility and Sterility2004,3,82:1
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