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| 1 | Role of hepatocyte nuclear factor 4-alpha in gastrointestinal and liver diseases显示文摘Hepatocyte nuclear factor 4-alpha(HNF4α)is a highly conserved member of nuclear receptor superfamily of ligand-dependent transcription factors that is expressed in liver and gastrointestinal organs(pancreas,stomach,and intestine).In liver,HNF4αis best known for its role as a master regulator of liver-specific gene expression and essential for adult and fetal liver function.Dysregulation of HNF4αexpression has been associated with many human diseases such as ulcerative colitis,colon cancer,maturity-onset diabetes of the young,liver cirrhosis,and hepatocellular carcinoma.However,the precise role of HNF4αin the etiology of these human pathogenesis is not well understood.Limited information is known about the role of HNF4αisoforms in liver and gastrointestinal disease progression.There is,therefore,a critical need to know how disruption of the expression of these isoforms may impact on disease progression and phenotypes.In this review,we will update our current understanding on the role of HNF4αin human liver and gastrointestinal diseases.We further provide additional information on possible use of HNF4αas a target for potential therapeutic approaches. | Matthew M Yeh Dustin E Bosch Sayed S Daoud | 2019 | World Journal of Gastroenterology2019，25，30： | 5 |
| 2 | Probability of successful defibrillation at multiples of the defibrillation energy requirernent in patients with an implantable defibrillator显示文摘 | Strickberger S A Daoud E G David son T | | 0，，： | 1 |
| 3 | Self-cleaning Cotton Functionalized withTiO2/SiOz: Focus on the Role of Silica 显示文摘 | Pakdel E Daoud W A | 2013 | Colloid and Interface Science2013，401，7： | 1 |
| 4 | Strain energy release rate for a circular-arc edge crack in a bar under tension or bending 显示文摘 | Daoud O E K Cartwright D J | 1985 | Journal of Strain Analysis for Engineering Design1985，20，1： | 1 |
| 5 | Strain energy release rate for a circular arc edge crack in a bar under tension or bending 显示文摘 | Daoud O E K Cartwright D J | 1985 | Journal of Strain Analysis for Engineering Design1985，20，1： | 1 |
| 6 | Vasculitis secondary to staphylococcal Protein A immunoadsorption (prosorba column) treatment in rheumatoid arthritis显示文摘 | Deodhar A Allen E Daoud K | 2002 | Semin Arthritis Rheum2002，32，1： | 1 |
| 7 | CA125 Concentrations in mlignant and nonmalignant disease显示文摘 | Daoud E Bodor G Weavew CH | | 0，，01： | 1 |
| 8 | Accuracy of the unipolar electrogram for identification of the site of origin of ventricular activa-tion显示文摘 | Man K C Daoud E G Knight B P | | 0，，： | 1 |
| 9 | Effect of irregular ventricular rhythm on cardiac output显示文摘 | Daoud E Weiss R Bahu M | 1996 | Am J Cardiol1996，78，： | 1 |
| 10 | Ablate and pace with cardiac resynchronization therapy for patients with reduced ejection fraction:Subgroup analysis of PAVE study显示文摘 | Daoud E Doshi R Fellows C | | Heart Rhythm0，，： | 1 |
| 11 | Pharrna- cokinetics of midazolam during continuous infusion in critically ill neonates显示文摘 | Jacqz-Aigrain E Daoud P Burtin P | 1992 | Eur J Clin Pharmacol1992，42，3： | 1 |
| 12 | Comparison of atrial-His intervals during tachycardia and during atrial pacing in patients with long RP tachycardia显示文摘 | Man KC Niebauer M Daoud E | 1995 | J Cardiovasc Electrophysiol1995，6，： | 1 |
| 13 | Transvenous catheter eryoablation for treatment of atrial fibrillation: Results of a feasibility study显示文摘 | Hoyt RH Wood M Daoud E | 2005 | PACE2005，，： | 1 |
| 14 | Atrioventricular node properties in patients with accessory pathway 显示文摘 | Niebauer M J Daoud E Goyal R | 1996 | Am Heart J1996，131，4： | 1 |
| 15 | Shortterm effect of atrial fibrillation on atrial contractile function in humans显示文摘 | DAOUD E G MARCOVITZ P KNIGHT B P | 1999 | Circulation1999，99，23： | 1 |
| 16 | MR imaging features of tuberculosis of the sellar region显示文摘 | Daoud E Mezghani S Fourati H | 2011 | J Radiol2011，92，78： | 1 |
| 17 | Expression of cFABP and PPAR in trophoblast cells: effect of PPAR ligands on linoleic acid uptake and differentiation显示文摘 | Daoud G Simoneau L Masse A Rassart E Lafond J | 2005 | Biochim Biophys Acta2005，1687，13： | 1 |
| 18 | Effect of atrial fibrillationon atrial refractoriness in human显示文摘 | Daoud E G Bogun F Goyal R | 1996 | Circulation1996，94，7： | 1 |
| 19 | Effect of verapamil and procainamide on atrial fibrillation-induced electrical remodeling in humans显示文摘 | Knight B Weiss R | 1997 | Circuation1997，96，： | 1 |
| 20 | Diffuse axonal injury in patients with head injuries:an epidemiologic and prognosis study of 124 cases显示文摘 | CHELLY H CHAARI A DAOUD E | 2011 | J Trauma2011，71，4： | 1 |
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