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| 1 | Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations显示文摘 | Thompson MC Fuller C Hogg TL Dalton J Finkelstein D Lau CC Chintagumpala M Adesina A Ashley DM KeUie SJ Taylor MD Curran T Gajjar A Gilbertson RJ | 2006 | 中国神经肿瘤杂志2006,4,1: | 17 |
| 2 | Hepatitis E virus in patients with acute severe liver injury显示文摘AIM: To examine the incidence of hepatitis E(HepE) in individuals with acute liver injury severe enough to warrant treatment at a transplant unit.METHODS: Hepatitis E virus(HEV) is an emerging pathogen in developed countries causing severe illness, particularly in immunocompromised patients or those with underlying chronic liver disease. HepE infection isoften under diagnosed, as clinicians can be reluctant to test patients who have not travelled to regions traditionally considered hyperendemic for HepE. There are few data regarding the significance of HEV in patients with very severe acute liver injury in developed countries. Eighty patients with acute severe liver injury attending the Scottish Liver Transplant unit were tested for HEV and anti-HEV IgG and IgM. Severe acute liver injury was defined as a sudden deterioration in liver function confirmed by abnormal liver function tests and coagulopathy or presence of hepatic encephalopathy. Eighty percent of these patients were diagnosed with paracetomol overdose. No patients had a history of chronic or decompensated chronic liver disease at time of sampling. IgG positive samples were quantified against the World Health Organization anti-HEV IgG standard. Samples were screened for HEV viral RNA by quantitative reverse transcription polymerase chain reaction.RESULTS: Four cases of hepatitis E were identified. Three of the four cases were only diagnosed on retrospective testing and were initially erroneously ascribed to drug-induced liver injury and decompensated chronic liver disease, with the cause of the decompensation uncertain. One case was caused by HEV genotype 1 in a traveller returning from Asia, the other three were autochthonous and diagnosed on retrospective testing. In two of these cases(where RNA was detected) HEV was found to be genotype 3, the most prevalent genotype in developed countries. Three patients survived, two of whom had been misdiagnosed as having drug induced liver injury. The fourth patient died from sepsis and liver failure precipitated as a result of hepatitis E infection and previously undiagnosed cirrhosis. Histopathology data to date is limited to mainly that seen for endemic HepE. All patients, with the exception of patient 1, demonstrated characteristics of HepE infection, as seen in previously described locally acquired cases.CONCLUSION: In patients with acute severe liver injury, HEV testing should be part of the initial diagnostic investigation algorithm irrespective of suspected initial diagnosis, age or travel history. | Claire Louise Crossan Kenneth J Simpson Darren G Craig Christopher Bellamy Janice Davidson Harry R Dalton Linda Scobie | 2014 | World Journal of Hepatology2014,6,6: | 4 |
| 3 | Time Domain Reflectometry : Simultaneous Measurement of Soil Water Content and Electrical Conductivity with a Single Probe 显示文摘 | DALTON F N HERKELRATH W N RAWLINS D S RHOADES J D | 1984 | Science1984,224,: | 1 |
| 4 | Selective interaction of a semiconjugated organic polymer with single-wall nanotubes 显示文摘 | Dalton A Stephan C Coleman J N | 2000 | J Phys Chem B2000,104,10: | 1 |
| 5 | Transgenic zebrafish as sentinels for aquatic pollution显示文摘 | Carvan M J Dalton T P Stuart G W | 2000 | Ann N Y Acad Sci2000,919,: | 1 |
| 6 | A functional conjugated polymer to process, purify and selectively interact with single wall carbon nanotubes 显示文摘 | Dalton A Blau W J Chambers G | 2001 | Synth Metals2001,121,: | 1 |
| 7 | Number of Directors and Financial Perfomance: A Meta- analysis显示文摘 | Dalton D Daily C Johnson J Ells'wand A | 1999 | Academy of Management Journal1999,,42: | 1 |
| 8 | A survey of tourist ope- rator attitudes to renewable energy supply in Queensland,Aus- tralia显示文摘 | Dalton G J Lockington D A Baldock T E | 2007 | ScienceDirect2007,32,: | 1 |
| 9 | Fluorescence intensity and squeezing in a driving three-level atom:ladder case显示文摘 | Ficek Z Dalton B J Knight P L | 1995 | Phys Rev1995,51,5: | 1 |
| 10 | Dynamic surface tension and adsorption mechanisms of surfactants at the air-water interface 显示文摘 | EASTOE J DALTON J | 2000 | Adv Colloid Interface Sci2000,85,: | 1 |
| 11 | Influence of therapeutic hypothermia on matrix metalloproteinase activity after traumatic brain injury in rats 显示文摘 | Truettner J S Alonso O F Dalton Dietrich W | 2005 | Cereb Blood Flow Metab2005,25,11: | 1 |
| 12 | An outbreak of gastroenteritis and fever due to Listeria monocytogenes in milk 显示文摘 | Dalton CB Austin CC Sobe! J | 1997 | N Engl J Med1997,336,2: | 1 |
| 13 | Purification, prop- erties, and distribution of ascorbate peroxidase in legume root nodules 显示文摘 | Dalton D A Hanus J F Russell S A | 2006 | Plant Physiol2006,83,: | 1 |
| 14 | Effects of antiagglomerants on the interactions between hydrate particles显示文摘 | Mark R A J Dalton Y Luke H | 2007 | American Institute of Chemical Engineers2007,54,2: | 1 |
| 15 | Increeased serum neopterin leveels in adults with Donm syndrome 显示文摘 | Mehta P D Patarick B A Dalton A J | 2005 | J Neuroimmunol2005,164,2: | 1 |
| 16 | Case study feasibility analysis of renewable energy supplyoptions for small to medium-sized tourist accommodations显示文摘 | Dalton G J Lockington D A Baldock T E | 2009 | Renewable Energy2009,34,4: | 1 |
| 17 | Cell cycle control of embryonic stem cells显示文摘 | WHITE J DALTON S | 2005 | Stem Cell Rev2005,1,2: | 1 |
| 18 | The viscoelastic properties of muscle-tendon units 显示文摘 | TAY LOR D C DALTON J SEABER A V | 1990 | Am J Sports Med1990,18,: | 1 |
| 19 | Hierarchical browsing and search of large image databases显示文摘 | Chen J Bouman C Dalton J | 2000 | IEEE Trans on Image Processing2000,9,3: | 1 |
| 20 | Progress in development of liver fluke vaccines显示文摘 | SPITHILL T W DALTON J P | 1998 | Arasitolgy1998,57,: | 1 |