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| 1 | Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations显示文摘 | Thompson MC Fuller C Hogg TL Dalton J Finkelstein D Lau CC Chintagumpala M Adesina A Ashley DM KeUie SJ Taylor MD Curran T Gajjar A Gilbertson RJ | 2006 | 中国神经肿瘤杂志2006，4，1： | 17 |
| 2 | Deep sedation during gastrointestinal endoscopy: Propofol-fentanyl and midazolam-fentanyl regimens显示文摘AIM: To compare deep sedation with propofol-fentanyl and midazolam-fentanyl regimens during upper gastrointestinal endoscopy. METHODS: After obtaining approval of the research ethics committee and informed consent, 200 patients were evaluated and referred for upper gastrointestinal endoscopy. Patients were randomized to receive propofol-fentanyl or midazolam-fentanyl (n = 100/group).We assessed the level of sedation using the observer's assessment of alertness/sedation (OAA/S) score and bispectral index (BIS). We evaluated patient and physician satisfaction, as well as the recovery time and complication rates. The statistical analysis was performed using SPSS statistical software and included the MannWhitney test, χ 2 test, measurement of analysis of variance, and the κ statistic. RESULTS: The times to induction of sedation, recovery, and discharge were shorter in the propofolfentanyl group than the midazolam-fentanyl group. According to the OAA/S score, deep sedation events occurred in 25% of the propofol-fentanyl group and 11% of the midazolam-fentanyl group (P = 0.014). Additionally, deep sedation events occurred in 19% of the propofol-fentanyl group and 7% of the midazolamfentanyl group according to the BIS scale (P = 0.039). There was good concordance between the OAA/S score and BIS for both groups (κ = 0.71 and κ = 0.63, respectively). Oxygen supplementation was required in 42% of the propofol-fentanyl group and 26% of the midazolam-fentanyl group (P = 0.025). The mean time to recovery was 28.82 and 44.13 min in the propofolfentanyl and midazolam-fentanyl groups, respectively (P < 0.001). There were no severe complications in either group. Although patients were equally satisfied with both drug combinations, physicians were more satisfied with the propofol-fentanyl combination. CONCLUSION: Deep sedation occurred with propofolfentanyl and midazolam-fentanyl, but was more frequent in the former. Recovery was faster in the propofol-fentanyl group. | Marcos Eduardo Lera dos Santos Fauze Maluf-Filho Dalton Marques Chaves Sergio Eiji Matuguma Edson Ide Gustavo de Oliveira Luz Thiago Ferreira de Souza Fernanda C Simoes Pessorrusso Eduardo Guimares Hourneaux de Moura Paulo Sakai | 2013 | World Journal of Gastroenterology2013，19，22： | 16 |
| 3 | Femtojoule electro-optic modulation using a silicon– organic hybrid device显示文摘Energy-efficient electro-optic modulators are at the heart of short-reach optical interconnects,and silicon photonics is considered the leading technology for realizing such devices.However,the performance of all-silicon devices is limited by intrinsic material properties.In particular,the absence of linear electro-optic effects in silicon renders the integration of energy-efficient photonic–electronic interfaces challenging.Silicon–organic hybrid(SOH)integration can overcome these limitations by combining nanophotonic silicon waveguides with organic cladding materials,thereby offering the prospect of designing optical properties by molecular engineering.In this paper,we demonstrate an SOH Mach–Zehnder modulator with unprecedented efficiency:the 1-mm-long device consumes only 0.7 fJ bit^(-1) to generate a 12.5 Gbit s^(-1) data stream with a bit-error ratio below the threshold for hard-decision forward-error correction.This power consumption represents the lowest value demonstrated for a non-resonant Mach–Zehnder modulator in any material system.It is enabled by a novel class of organic electro-optic materials that are designed for high chromophore density and enhanced molecular orientation.The device features an electro-optic coefficient of r33<180 pm V^(-1) and can be operated at data rates of up to 40 Gbit s^(-1). | Sebastian Koeber Robert Palmer Matthias Lauermann Wolfgang Heni Delwin L Elder Dietmar Korn Markus Woessner Luca Alloatti Swen Koenig Philipp C Schindler Hui Yu Wim Bogaerts Larry R Dalton Wolfgang Freude Juerg Leuthold Christian Koos | 2015 | Light(Science & Applications)2015，4，1： | 4 |
| 4 | 选择性雄激素受体调节剂治疗迟发性男性性腺功能低下症显示文摘几种睾酮制剂用于治疗老年男性性腺功能减退。这些疗法在其便利性、灵活性、区域供应和费用等方面有区别,但有共同的药代动力学基础,同时缺乏长期安全性数据。简洁和成本较低的基于药代动力学的注册临床试验使得开发改善性的治疗迟发性性腺功能减退的新疗法的商业动机减少了。在前列腺、头发、皮肤受雄激素缺乏影响的患者中,选择性雄激素受体调节剂已被证明可以提供合成代谢的好处。(目前,选择性雄激素受体调节剂的临床进展集中在有限定身体功能的临床终点的急性肌肉萎缩和低体重)。在具有有益的药理、理想的药代动力学的选择性雄激素受体调节剂应用于治疗迟发性男性性腺功能低下症前,其在男性性腺功能低下治疗中关于临床缺陷的更清晰的监管是必须的。 | Christopher C Coss Amanda Jones Michael L Hancock Mitchell S Steiner James T Dalton | 2014 | Asian Journal of Andrology2014，16，2： | 3 |
| 5 | Selective interaction of a semiconjugated organic polymer with single-wall nanotubes 显示文摘 | Dalton A Stephan C Coleman J N | 2000 | J Phys Chem B2000，104，10： | 1 |
| 6 | Antidepressant medications and risk for cancer显示文摘 | Johansen C Mellemkjaer L | 2000 | Epidemiology2000，11，2： | 1 |
| 7 | Number of Directors and Financial Perfomance: A Meta- analysis显示文摘 | Dalton D Daily C Johnson J Ells'wand A | 1999 | Academy of Management Journal1999，，42： | 1 |
| 8 | Micro-scalemeasurement of the mechanical properties of com-pressed pharmaceutical powders (2):The dynamic moduli of microcrystalline cellulose显示文摘 | Dalton C R Clas S-D | 2001 | Int JPharm2001，228，12： | 1 |
| 9 | Initial public offering investor valuations: an examination of top management team prestige and environmental uncertainty 显示文摘 | Lester R H Certo S T Dalton C M Dalton D R Cannella A A | 2006 | Journal of Small Business Management2006，44，1： | 1 |
| 10 | Dimethylarginines in chronic renal failure 显示文摘 | Wahbi N Dalton RN Turner C | 2001 | Clin Pathol2001，54，6： | 1 |
| 11 | A decade of corporate women: Some progress in the boardroom, none in the executive suite显示文摘 | Daily C Certo T and Dalton D | 1999 | Strategic Management Journal1999，20，1： | 1 |
| 12 | The viscoelastic properties of muscle-tendon units 显示文摘 | TAY LOR D C DALTON J SEABER A V | 1990 | Am J Sports Med1990，18，： | 1 |
| 13 | Hierarchical browsing and search of large image databases显示文摘 | Chen J Bouman C Dalton J | 2000 | IEEE Trans on Image Processing2000，9，3： | 1 |
| 14 | Continuous dielectrophoretic cell seperation microfluidic device 显示文摘 | Li Y Dalton C Crabtree H J | 2007 | Lab Chip2007，7，： | 1 |
| 15 | Composition of the top management team and firm international diversification 显示文摘 | Tihanyi L Ellstrand A E Daily C M Dalton D R | 2000 | Journal of Management2000，26，6： | 1 |
| 16 | The levonorgestrel - releasing intrauterine system: an updated review of the contraceptive and noncontraceptive uses 显示文摘 | Chrisman C Ribeiro P Dalton VK | 2007 | Clin Obstet Gynecol2007，50，4： | 1 |
| 17 | Outpatient management of patients with low-risk upper-gastrointestinal haemorrhage: multicentre validation and prospective evaluation显示文摘 | AJ Stanley D Ashley HR Dalton C Mowat DR Gaya E Thompson U Warshow M Groome A Cahill G Benson O Blatchford W Murray | 2009 | The Lancet2009，，9657： | 1 |
| 18 | Characteristics of a widespread community cluster of H275Y oseltamivir-resistant A (H1N1) pdm09 influenza in Australia显示文摘 | Hurt A C Hardie K Wilson N J Deng Y M Oshourn M Leang S K Lee R T Iannello P Gehrig N Shaw R Wark P Caldwell N Givney R C Xue L Maurer- Stroh S Dwyer D E Wang B Smith D W Levy A Booy R Dixit R Merritt T Kelso A Dalton C Durrheim D Barr I G | 2012 | J Infect Dis2012，206，2： | 1 |
| 19 | Composition of the Top Management Team and Firm International Diversification显示文摘 | TIHANY1 L ELLSTRAND A E DAILY C M DALTON D R | 2000 | Jour- nal of Management2000，26，6： | 1 |
| 20 | The production of leukaemia inhibitory factor by human endometrium:presence in uterine flushings and production by cells in culture 显示文摘 | LAIRD S M TUCHgRMAN E M DALTON C F | 1997 | Hum Reprod1997，12，： | 1 |
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