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| 1 | Nuclear Aurora kinase A switches m^(6)A reader YTHDC1 to enhance an oncogenic RNA splicing of tumor suppressor RBM4显示文摘Aberrant RNA splicing produces alternative isoforms of genes to facilitate tumor progression,yet how this process is regulated by oncogenic signal remains largely unknown.Here,we unveil that non-canonical activation of nuclear AURKA promotes an oncogenic RNA splicing of tumor suppressor RBM4 directed by m^(6)A reader YTHDC1 in lung cancer.Nuclear translocation of AURKA is a prerequisite for RNA aberrant splicing,specifically triggering RBM4 splicing from the full isoform(RBM4-FL)to the short isoform(RBM4-S)in a kinase-independent manner. | SiSi Li YangFan Qi JiaChuan Yu YuChao Hao Bin He MengJuan Zhang ZhenWei Dai TongHui Jiang SuYi Li Fang Huang Ning Chen Jing Wang MengYing Yang DaPeng Liang Fan An JinYao Zhao WenJun Fan YuJia Pan ZiQian Deng YuanYuan Luo Tao Guo Fei Peng ZhiJie Hou ChunLi Wang FeiMeng Zheng LingZhi Xu Jie Xu QingPing Wen BiLian Jin Yang Wang Quentin Liu | 2022 | Signal Transduction and Targeted Therapy2022,7,5: | 4 |
| 2 | Weight Distributions of Two Classes of Linear Codes from Perfect Nonlinear Functions显示文摘 | DAI Qingping LI Chao | 2009 | Chinese Journal of Electronics2009,18,3: | 4 |
| 3 | On the differential uniformities of functions over finite fields显示文摘In this paper, the possible value of the differential uniformity of a function over finite fields is discussed. It is proved that, the differential uniformity of a function over Fq can be any even integer between 2 and q when q is even; and it can be any integer between 1 and q except q-1 when q is odd. Moreover, for any possible differential uniformity t, an explicit construction of a differentially t-uniform function is given. | QU LongJiang LI Chao DAI QingPing KONG ZhiYin | 2013 | Science China Mathematics2013,56,7: | 4 |
| 4 | Maternal genetic history of southern East Asians over the past 12,000 years显示文摘Southern East Asia,including Guangxi and Fujian provinces in China,is home to diverse ethnic groups,languages,and cultures.Previous studies suggest a high complexity regarding population dynamics and the history of southern East Asians.However,large-scale genetic studies on ancient populations in this region are hindered by limited sample preservation.Here,using highly efficient DNA capture techniques,we obtain 48 complete mitochondrial genomes of individuals from Guangxi and Fujian in China and reconstruct their maternal genetic history over the past 12,000 years.We find a strong connection between southern East Asians dating to~12,000-6000 years ago and present-day Southeast Asians.In addition,stronger genetic affinities to northern East Asians are observed in historical southern East Asians than Neolithic southern East Asians,suggesting increased interactions between northern and southern East Asians over time.Overall,we reveal dynamic connections between ancient southern East Asians and populations located in surrounding regions,as well as a shift in maternal genetic structure within the populations over time. | Yalin Liu Tianyi Wang Xichao Wu Xuechun Fan Wei Wang Guangmao Xie Zhen Li Qingping Yang Peng Cao Ruowei Yang Feng Liu Qingyan Dai Xiaotian Feng Wanjing Ping Bo Miao Yun Wu Yichen Liu Qiaomei Fu | 2021 | Journal of Genetics and Genomics2021,48,10: | 1 |
| 5 | Novel Ag-bridged dual Z-scheme g-C_(3)N_(4)/BiOI/AgI plasmonic heterojunction: Exceptional photocatalytic activity towards tetracycline and the mechanism insight显示文摘Rational design and synthesis of highly efficient and robust photocatalysts with positive exciton splitting and interfacial charge transfer for environmental applications is critical.Herein,aiming at overcoming the common shortcomings of traditional photocatalysts such as weak photoresponsivity,rapid combination of photo-generated carriers and unstable structure,a novel Ag-bridged dual Z-scheme g-C_(3)N_(4)/BiOI/AgI plasmonic heterojunction was successfully synthesized using a facile method.Results showed that Ag-AgI nanoparticles and three-dimensional(3D)BiOI microspheres were decorated highly uniformly on the 3D porous g-C_(3)N_(4) nanosheet,resulting in a higher specific surface area and abundant active sites.The optimized 3D porous dual Z-scheme g-C_(3)N_(4)/BiOI/Ag-AgI manifested exceptional photocatalytic degradation efficiency of tetracycline(TC)in water with approximately 91.8%degradation efficiency within 165 min,outperforming majority of the reported g-C_(3)N_(4)-based photocatalysts.Moreover,g-C_(3)N_(4)/BiOI/Ag-AgI exhibited good stability in terms of activity and structure.In-depth radical scavenging and electron paramagnetic resonance(EPR)analyses confirmed the relative contributions of various scavengers.Mechanism analysis indicated that the improved photocatalytic performance and stability were ascribed to the highly ordered 3D porous framework,fast electron transfer of dual Z-scheme heterojunction,desirable photocatalytic performance of BiOI/AgI and synergistic effect of Ag plasmas.Therefore,the 3D porous Z-scheme g-C_(3)N_(4)/BiOI/Ag-AgI heterojunction had a good prospect for applications in water remediation.The current work provides new insight and useful guidance for designing novel structural photocatalysts for environment-related applications. | Wenxia Wang Zhen Li Kailin Wu Guodong Dai Qingping Chen Lihua Zhou Junxia Zheng Liang Ma Guiying Li Wanjun Wang Taicheng An | 2023 | Journal of Environmental Sciences2023,,9: | 0 |