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7篇 您的检索式：作者名="D.Sun"

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		题名	作者	年代	出处	被引量
	1	Crosslinked hydrogels--a promising class of insoluble solid molecular dispersion carriers for enhancing the delivery of poorly soluble drugs显示文摘Water-insoluble materials containing amorphous solid dispersions(ASD)are an emerging category of drug carriers which can effectively improve dissolution kinetics and kinetic solubility of poorly soluble drugs.ASDs based on water-insoluble crosslinked hydrogels have unique features in contrast to those based on conventional water-soluble and water-insoluble carriers.For example,solid molecular dispersions of poorly soluble drugs in poly(2-hydroxyethyl methacrylate)(PHEMA)can maintain a high level of supersaturation over a prolonged period of time via a feedback-controlled diffusion mechanism thus avoiding the initial surge of supersaturation followed by a sharp decline in drug concentration typically encountered with ASDs based on water-soluble polymers.The creation of both immediate-and controlled-release ASD dosage forms is also achievable with the PHEMA based hydrogels.So far,ASD systems based on glassy PHEMA have been shown to be very effective in retarding precipitation of amorphous drugs in the solid state to achieve a robust physical stability.This review summarizes recent research efforts in investigating the potential of developing crosslinked PHEMA hydrogels as a promising alternative to conventional water-soluble ASD carriers,and a related finding that the rate of supersaturation generation does affect the kinetic solubility profiles implications to hydrogel based ASDs.	Dajun D.Sun Ping I.Lee	2014	Acta Pharmaceutica Sinica B2014，4，1：	2
	2	Netherton syndrome: A case report and review of the literature显示文摘	Joannie D.Sun Kenneth G.Linden	2005	International Journal of Dermatology2005，，6：	1
	3	Feedback control of traffic jam based on the full velocity difference car-following model显示文摘	Y.LI D.SUN W.LIU		0，，03：	1
	4	A novel 62‐bp indel mutation in the promoter region of transforming growth factor‐beta 2 (TGFB2) gene is associated with body weight in chickens显示文摘	S.Tang J.Ou D.Sun Y.Zhang G.Xu Y.Zhang	2011	Animal Genetics2011，，1：	1
	5	Electrohydrodynamic deposition of polymeric droplets under low-frequency pulsation显示文摘	L.Xu X.Wang T.Lei D.Sun L.Lin		0，，10：	1
	6	Electrohydrodynamic Printing under Applied Pole-Type Nozzle Configuration显示文摘	L.Xu D.Sun		0，，02：	1
	7	Editorial显示文摘The research process for new drug is complicated,time-consum-ing,and costly.Thousands of chemical compounds must be made and tested in an effort to find one that can achieve a desirable result.It may take approximately ten years to study and test a new drug before it can be approved for the general public.However,in today's pharmaceutical industry drug delivery has become keys in drug product development.New innovative pharmaceutical technologies allow for increased performance of new and existing pharmaceutical compounds.	Dajun D.Sun Ping I.Lee	2014	Acta Pharmaceutica Sinica B2014，4，1：	0

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