| 3 | 女性青少年的安全套使用情况、性行为以及患性传播性疾病与生殖器人乳头状瘤病毒感染持续时间的关系显示文摘Objective:To examine the association of potentially modifiable factors such a s condom use,sexual behaviors,and concurrent sexually transmitted infections w ith duration of genital human papillomavirus(HPV)infections among adolescent w omen.Design:Longitudinal observational study.Setting:Study conducted at 3 in ner-city clinics in Indianapolis,Ind.Participants:Forty-nine HPV-positive adolescents were tested frequently for HPV infection and provided sexual behavio r diaries.Main Exposures:Condom use,sexual behaviors,number of partners,and concurrent infections with Neisseria gonorrhoeae,Chlamydia trachomatis,and Tr ichomonas vaginalis.Main Outcome Measures:Time from onset to clearance of type specific HPV infections was analyzed with proportional hazard models.Adjusted h azard ratios(AHRs)were used to assess the effects of risk factors on the durat ion of HPV infection.Because viral clearance is a preferred outcome,a variable with an AHR less than 1 was considered a risk factor(ie,associated with reduc ed chance of viral clearance and prolonged infection).Results:Prolonged HPV in fection was associated with oncogenic HPV types(AHR,0.58 [95%confidence inter val(CI),0.39-0.84])less than median level of condom use during an HPV infect ion(AHR,0.53 [95%CI,0.33-0.84])and coinfection with Ctrachomatis(AHR,0.5 8 [95%CI,0.31-0.89])or T vaginalis(AHR,0.32 [95%CI,0.16-0.64]).Not hav ing multiple sexual partners during an HPV infection was associated with early H PV clearance(AHR,5.52 [95%CI,3.28-9.30]).Conclusions:These findings suppo rt public health messages of reducing the number of sexual partners,promoting r outine condom use,and frequent sexually transmitted infection screening that ma y be beneficial with HPV infections. | Shew M.L. Fortenberry J.D. D.R.Brown 俞晓梅 | 2006 | 世界核心医学期刊文摘(儿科学分册)2006，2，8： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员