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| 1 | 乌干达在接受抗病毒治疗的艾滋病病人中筛查活动性结核病的一个简单工具显示文摘背景:在撒哈拉以南非洲地区,采用可靠的临床程序,对开始接受或已经接受抗病毒治疗的艾滋病病人进行活动性结核病筛查,可减少对诊断程序的需要。方法:我们对6个与结核病相关的症状和体征单独或组合在一起的效用进行了估计,并与乌干达卫生部对现患结核病(在评估抗病毒治疗资格时,作为基线)、抗病毒治疗早期(抗病毒治疗开始后的3个月内)结核病和新发结核病(抗病毒治疗3个月以后)的诊断指南进行了比较。结果:在1 995例接受抗病毒治疗资格筛查的HIV感染者中,71例(3.6%)被诊断患有结核病。对于预测活动性结核病而言,下列任一症状或体征:咳嗽≥3周,发热≥4周,淋巴结肿大或基线体质量指数≥18 kg/m^2,其灵敏度为99%(95%可信区间为96~100),特异度66%(95%可信区间为64~68),阴性预测值为100%(95%可信区间为99~100)。在抗病毒治疗随访期间,结核病发病率为2.4/100人年(95%可信区间为1.6~3.4)。出现咳嗽≥3周或全身乏力症状或体征的灵敏度为100%(95%可信区间为99~100),特异度为66%(95%可信区间为59~74),阴性预测值为100%(95%可信区间为99~100)。结论:在资源贫乏的非洲地区,应用简单的结核病筛查流程,可以准确地辨别出哪些HIV感染者需要接受进一步的结核诊断检查。 | W.Were D.Moore P.Ekwaru G.Mwima R.Bunnell F.Kaharuza G.Rutherford J.Mermin 刘二勇(译) 王雪静(校) | 2010 | 国际结核病与肺部疾病杂志2010，，2： | 1 |
| 2 | A Small Molecule Modulator of Prion Protein Increases Human Mesenchymal Stem Cell Lifespan, Ex Vivo Expansion, and Engraftment to Bone Marrow in NOD/SCID Mice显示文摘 | Sindhu T.Mohanty Claire J.Cairney Andrew D.Chantry SanjeevMadan James A.Fernandes Steven J.Howe Harry D.Moore Mark J.Thompson BeiningChen AdrianThrasher W. NicolKeith IlariaBellantuono | 2012 | STEM CELLS2012，，6： | 1 |
| 3 | 防火研究基金会的25年历程显示文摘在过去的25年间,防火研究基金会配合国家防火协会为火灾及保障群众的生命安全做出了不懈的努力。国家防火协会对技术规范及标准的需要是防火研究基金会成立的重要原因。国家防火协会的成员及董事会认识到技术规范及标准的迫切必要性.因此,在1982年批准成立了国家防火研究基金会(即现在的防火研究基金会)。根据1982年国家防火协会的年度报告显示,当时基金会的的常务董事是约翰·杰勒德,洛杉矶消防队前队长, | Wayne D.Moore | 2008 | 亚洲消防2008，，4： | 0 |
| 4 | Quantification and discovery of PCR inhibitors found in food matrices commonly associated with foodborne viruses显示文摘Human norovirus is the leading cause of foodborne illness globally.Detection and quantification of norovirus commonly involves the use of reverse transcriptase quantitative polymerase chain reaction(RT-qPCR);however,the presence of inhibitory compounds in foods limit detection and accurate quantification.Although some studies have been done on PCR inhibitors from foods,many of them are over a decade old and do not investigate inhibition in contemporary one-step RT-qPCR-based detection chemistries.The purpose of this work was to quantify the degree of inhibition that occurs from inhibitory compounds found in produce(pectin)and mollusks(hemocyanin,glycogen)—foods commonly associated with norovirus outbreaks.RT-qPCR reactions containing different amounts of genomic bacteriophage MS2 RNA,a norovirus surrogate,were spiked with different concentrations of pectin(0.0625%–0.25%w/V),glycogen(1.25%–10%),and hemocyanin(0.0625%–0.25%).Past research has implicated glycogen as an inhibitory compound in oysters;however,even high levels of glycogen(10%)had no significant effect(P>0.05)on amplification.Conversely,both pectin and hemocyanin caused complete inhibition at 0.25%,with no significant inhibition observed at 0.0625%(P<0.05).Hemocyanin is abundant in the hemolymph of mollusks and previously untested as a PCR inhibitor.This work demonstrates that pectin and hemocyanin should be considered when testing produce and mollusk samples with PCR-based methods. | Cassandra Suther Matthew D.Moore | 2019 | Food Science and Human Wellness2019，8，4： | 0 |
| 5 | 喷涂胶结内衬修复后的腐蚀金属管道强度测试显示文摘通过喷涂胶结内衬的方法对埋于皇后大学地球工程实验室西侧试验坑的两根直径1.2m且底部(invert)被强烈腐蚀的金属管道进行了修复。在金属管道以及内部的衬板均装置有线性电位器(1inear poten-tiometers),传统应变传感器以及光纤应变传感器用于测量管道直径的变化。并分别在1.2m与2.1m的埋深下利用标准单轴和平衡悬架轴加载的方法对管道在工作荷载下的性能做了评估。之后在1.2m埋深下利用平衡悬架轴加载对管道的最大极限状态进行了测试。将管道从地底挖掘出后,观测了修复后的厚度剖面。本文简要说明了本次修复对管道在工作载荷下的变形与曲率产生的影响。之后对最大极限状态(包括裂纹的分布和抗表面载荷能力)进行了描述。本次试验所得结论已考虑加载过程中圆周弯矩和内衬裂纹的影响。 | David Becerril Garcia Ian D.Moore 邬明皓 | 2014 | 非开挖技术2014，，6： | 0 |
| 6 | Microbiota,Viral Infection,and the Relationship to Human Diseases:An Area of Increasing Interest in the SARS-CoV-2 Pandemic显示文摘The current severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)pandemic and its severe societal burden have underscored the importance of understanding eukaryotic viral infection and its relationship to both acute and secondary health effects.1,2 Many viruses,including SARS-CoV-2 in some instances,replicate in the enteric tract or have an indirect relationship with it.A growing area of focus has been to understand the relationship between the gut microbiota and viral infection,as some evidence suggests that certain bacteria or bacterial compositions can promote3–8 or inhibit7,9,10 viral pathogenesis.The gut microbiota has been implicated in affecting pathophysiology of local gut and many remote organs such as the lungs,liver,and brain.7 Although the interaction between viral replication and bacteria in the gut is an exciting growing area of focus,gaps still exist in understanding the effect enteric replication of some viruses has on the gut microbiome and if there are other health consequences of any of those changes. | Matthew D.Moore Cassandra Suther Yanjiao Zhou | 2021 | Infectious Microbes & Diseases2021，3，1： | 0 |
| 7 | WSV 2019: The First Committee Meeting of the World Society for Virology显示文摘The World Society for Virology(WSV) was founded and incorporated as a nonprofit organization in the United States in 2017. WSV seeks to strengthen and support both virological research and virologists who conduct research of viruses that affect humans, other animals, plants, and other organisms. One of the objectives of WSV is to connect virologists worldwide and support collaboration. Fulfilling this objective, virologists from fourteen countries in North America,Europe, Africa, Asia, and the Middle East met on 25–27 th August 2019 in Stockholm, Sweden at the Karolinska University Hospital for the first Committee Meeting of WSV. This meeting included compelling keynote and honorary speeches and a series of 18 scientific talks were given encompassing a diverse array of subjects within virology. Followed by the scientific session, a business session was held where multiple aspects and next steps of the society were discussed and charted out. | Ahmed S.Abdel-Moneim Matthew D.Moore Mahmoud M.Naguib Jesus L.Romalde Maria Soderlund-Venermo | 2020 | Virologica Sinica2020，35，2： | 0 |
| 8 | Pressure vessel priming analysis for a regulated liquid propulsion system显示文摘An investigation was performed to determine the pressure transient levels and time required to reach pressure equilibrium in a regulated liquid propulsion system due to the priming of a propellant tank during system initiation.An experimental fluid flow test setup was designed and fabricated using a pressure vessel to house distilled water as a propellant simulant for liquid hydrazine and high-pressure gaseous nitrogen as the pressurant.A snubber orifice was installed downstream of the high-pressure gaseous nitrogen bottles to protect a regulator from high-pressure transients,prior to the regulation of incoming gas to beginning of life propulsion system propellant tank conditions.Experiments were conducted to measure pressure transients and time to pressure equilibrium by varying initial system pressures,snubber orifice diameter,and system ullage volume.A mathematical model was developed and compared against the experimental regulated system priming results to predict the system pressures and time to reach system pressure equilibrium during the pressurization period for regulated propulsion systems given initial conditions. | Jeffrey D.Moore | 2020 | Propulsion and Power Research2020，9，2： | 0 |
| 9 | 怎样的提问才是好的提问显示文摘在新课改的今天,我们越来越关注教师的行动,课堂中的行动是什么,我们觉得是微观的各种控制教学行为的元素的改变,于是,编辑部花了不少力气,请了一些教师和专家来为我们共同捕捉这些变化,呈现出了'课堂教学技术研究'这个子栏目。 | Kenneth D.Moore 潘为国 高岚岚 韩妮嘉 陈洁 秦英辉 曹珺 | 2005 | 计算机教与学.现代教学2005，，5： | 0 |
| 10 | 诺卡菌病:附59例病例报告显示文摘 | Rocehelle P.Walensky Richard D.Moore | 2002 | 世界医学杂志2002，6，3： | 0 |
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