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| 1 | 新一代渴望导管: 在肺的栓塞的处理的可行性显示文摘 AIM: To report our preliminary experience with a new generation aspiration catheter in the treatment of symptomatic pulmonary embolism(PE). METHODS: A retrospective database search for pulmonary artery embolectomy since introduction of the Pronto.035' and XL extraction catheter(Vascular Solutions, Minneapolis, MN) at our institution in 10/2009 was performed. Ten consecutive patients were identified in which the Pronto.035' or XL catheter was used between 01/2010 and 03/2013. All patients were referred for catheter based embolectomy due to contraindications to systemic lysis, or for being in such a critical clinical condition that immediate percutaneous treatment deemed warranted. The computed tomography(CT) right to left heart ratio as predictor for the severity of the PE was retrospectively evaluated on standard axial views. The difference between pre- and post-procedure pulmonary pressure measures was taken to assess the procedural effect.RESULTS: Extensive PE was confirmed angiographically in all patients. Measured right- to left ventricle(RV/LV) ratios were elevated beyond one in seven of the eight available CTs. Acute procedural success defined as clinical removal of visible thrombus and improvement in mean pulmonary artery pressure was seen in all recorded patients(n = 8), the mean pulmonary pressures declined from a median(range) of 35.5(19-46) to 23(10-37, P = 0.008) mmHg. Neither death nor other complications occurred intra- or immediately periprocedural, yet short term mortality within 30 d was found in 6 out of 9 patients, one patient was lost in follow up. The cause of death within 30 d in the 6 patients was identified as: Circulatory failure in direct connection with the PE(n = 2), stroke, sepsis, or succumbing to malignancy in a hospice setting(n = 2). CONCLUSION: Success in thrombus removal with improved pulmonary hypertension and systemic hypotension suggests this aspiration technique to be effective. Aspiration catheters should be part of further trials. | Wolf E Heberlein Mollie E Meek Omar Saleh James C Meek Shelly Y Lensing William C Culp | 2013 | World Journal of Radiology2013，5，11： | 2 |
| 2 | Therapeutic applications of lipid-coated microbubbles显示文摘 | UNGER E C PORTER T CULP W | 2004 | Adv Drug Deliv Rev2004，56，9： | 1 |
| 3 | The whitehead hemorrhoidectonly:an unjustly maligned Procedure显示文摘 | WOLFF B G CULP C E | 1988 | Dis Colon Rectum1988，31，8： | 1 |
| 4 | Microbubbles potentiated ultrasound as a method of stroke therapy in a pig model:preliminary findings显示文摘 | Culp W C Erdem E Roberson P K | 2003 | J Vasc lnterv Radiol2003，14，11： | 1 |
| 5 | Identification of the natu- ral bacterial microflora on the skin of Eastern newts, bullfrog tadpoles and Redback salamanders显示文摘 | Culp C E Falkinham J O Belden L K | 2007 | Heipetologica2007，63，： | 1 |
| 6 | The rapeutic applications of lipid coated microbubbles显示文摘 | Unger E C Porter T Culp W | 2004 | Advanced Drug Delivery Reviews2004，56，9： | 1 |
| 7 | Cadmium toxicity and uptake by mats of the freshwater diatom:navicula pelliculosa(Br,b)hilse显示文摘 | IRVING E C BAIRD D J CULP J M | 2009 | Archives of Environmental Contamination and Toxicology2009，57，： | 1 |
| 8 | The Whiehead hemorrhoidectomy:an unjustly maligned procedure显示文摘 | Wolff B G Culp C E | 1988 | Dis Colon Tectum1988，31，8： | 1 |
| 9 | Therapeutic applications of lipid-coated microbubbles 显示文摘 | Unger E C Porter T Culp W | 2004 | Adv Drug Deliv Rev2004，56，9： | 1 |
| 10 | Microbubble po- tentiated ultrasound as a method of stroke therapy in a pig model: preliminary findings显示文摘 | Culp W C Erdem E Roberson P K | 2003 | J Vasc Interv Radiol2003，14，11： | 1 |
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