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281篇 您的检索式:作者名="CuffS"
    题名 作者 年代 出处 被引量
1Role of Positive Selection Pressure on the Evolution of H5N1 Hemagglutinin显示文摘The surface glycoprotein hemagglutinin (HA) helps the influenza A virus to evade the host immune system by antigenic variation and is a major driving force for viral evolution. In this study, the selection pressure on HA of H5N1 influenza A virus was analyzed using bioinformatics algorithms. Most of the identified positive selection (PS) sites were found to be within or adjacent to epitope sites. Some of the identified PS sites are consistent with previous experimental studies, providing further support to the biological significance of our findings. The highest frequency of PS sites was observed in recent strains isolated during 2005–2007. Phylogenetic analysis was also conducted on HA sequences from various hosts. Viral drift is almost similar in both avian and human species with a progressive trend over the years. Our study reports new mutations in functional regions of HA that might provide markers for vaccine design or can be used to predict isolates of pandemic potential.Venkata R.S.K. Duvvuri Bhargavi Duvvuri Wilfred R. Cuff Gillian E. Wu Jianhong Wu 2009Genomics, Proteomics & Bioinformatics2009,7,1:6
2β-Elemene, a novel plant-derived antineoplastic agent, increases cisplatinchemosensitivity of lung tumor cells by triggering apoptosis显示文摘Qingdi Li Gangduo Wang Manchao Zhang Christopher Cuff Lan Huang Eddie Reed 2009Oncology Reports2009,,1:2
3Family and psychosocial risk factors in a longitudinal epidemiological study of adolescents显示文摘Cuffe S P Mckeown R E Addyc L et a1 2005J Am Acad Child Adolesc Psy-chiatry2005,44,2:1
4Metformin and the ATM DNA damage response ( DDR ) : accelerating the onset of stress-induced senescence to boost protection against cancer 显示文摘Menendez JA Cuff S Oliveras-Ferraros C 2011Aging( Albany NY)2011,3,11:1
5Thoracic paraver-tebral block using real -time ultrasound guidance 显示文摘0 Riain SC Donnell BO Cuffe T 2010Anesth Analg2010,110,:1
6A pooled explor- atory analysis of the effect of tumor size and KRAS muta- tions on survival benefit from adjuvant platinum-based chemotherapy in node-negative non-small cell lung cancer 显示文摘Cuffe S Bourredjem A Graziano S 2012J Thorac Oncol2012,7,6:1
7The effects of motorcycle helmet use between hospitals in states with and without a mandatory helmet law 显示文摘 Sullivan T CuffS 2002Corm Med2002,66,4:1
8Evaluation and Improvement of Multiple Sequence Methods for Protein Secondary Structure Prediction显示文摘CUFF J A BARTON G J 1999Proteins:Structure Function and Genetics1999,34,:1
9CDX2 is an amplified lineage -survival oncogene in colorectal cancer显示文摘Salari K Spulak ME Cuff J 2012Proc Natl Acad Sci USA2012,109,18:1
10Short-term intravenous milrinone for acute exacerbation of chronic heart failure:a randomized controlled trial显示文摘Cuffe MS Califf RM Adams KF Jr 2002JAMA2002,287,12:1
11A novel inhibitor of fatty acid syn- thase shows activity against I-IER2+ breast cancer xenografts and is ac- tive in anti-HER2 drug-resistant cell lines显示文摘Puig T Aguilar H Cuff S 2011Breast Cancer Res2011,13,6:1
12T-2 toxin impairment of enteric reovirus clearance in the mouse associated with sup pressed immunoglobulin and IFN-γ responses显示文摘LI M X CUFF C F PESTKA J J 2006Toxicology and Applied Pharmacology2006,214,3:1
13Application of enhanced multiple sequence alignment profiles to improve protein secondary structure prediction显示文摘CUFF J A BARTON G J 1999Proteins1999,40,:1
14A pooled exploratory analysis of the effect of tumor size and KRAS mutations on survival benefit from adjuvant platinum-based chemotherapy in node- negative non-small cell lung cancer显示文摘Cuffe S BomTedjem A Graziano S 2012J Thorac Oncol2012,7,6:1
15Weight loss and mortality of diree life stages of Tribolium castaneum (Herbst) when exposed to four modified atmospheres显示文摘Jay E G Cuff W 1981J Stored Prod Res1981,17,:1
16Application of multiple sequence alignment profiles to improve protein secondary structure prediction 显示文摘Cuff J A Barton G J 2000Proteins2000,40,:1
17Evaluation and Improvement of Multiple Sequence Methods for Protein Secondary Structure Prediction显示文摘CUFF J A BARTON G J 1999Proteins:Structure Function and Genetics1999,34,:1
18Short-term intravenous milrinone for acute exacerbation of chronic heart failure:a randomized controlled trial显示文摘Cuffe MS Califf RM Adams KF Jr 2002JAMA2002,287,12:1
19T-2 toxin impairment of enteficreovirus clearance in the mouse associated with suppressed immunoglobulin and IFN-C responses显示文摘Li M X Cuff C F Pestka J J 2006Toxicology and Applied Pharmacology2006,214,3:1
20Prognostic value of anxi- ety and depression in patients with chronic heart failure 显示文摘Jiang W Kuchibhatla M Cuffe MS 2004Circu- lation2004,110,22:1
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