|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 新一代低轨卫星网络和地面无线自组织网络融合技术的探讨显示文摘展示并验证了一种由新一代低轨卫星网络和地面无线自组织网络组成的星地一体化网络。此星地一体化网络中的低轨卫星网络可以提供大容量、低时延的网络覆盖,其'低轨'的特点又可减小地面终端的尺寸,增强地面网络的移动性。与经典的中轨和静止卫星网络相比,此种网络可以提供更高通量、更高移动性的通信支持,大大拓宽通信网络的应用范围。对不同的网络层次结构采用相应的软件仿真工具环境,为今后进一步深入研究卫星网络的体系结构和自组互联网技术起到了抛砖引玉的作用。 | 杨昕 孙智立 刘华峰 赵康僆 程子敬 苗晔 Haitham Cruickshank | 2016 | 中兴通讯技术2016，22，4： | 6 |
| 2 | Evidence for the involvement of NOD2 in regulating colonic epithelial cell growth and survival显示文摘AIM: To investigate the function of NOD2 in colonic epithelial cells (CEC). METHODS: A combination of in vivo and in vitro analyses of epithelial cell turnover in the presence and absence of a functional NOD2 protein and, in response to enteric Salmonella typhimurium infection, were used. shRNA interference was also used to investigate the consequences of knocking down NOD2 gene expression on the growth and survival of colorectal carcinoma cell lines. RESULTS:In the colonic mucosa the highest levels of NOD2 expression were in proliferating crypt epithelial cells. Muramyl dipeptide (MDP), that is recognized by NOD2, promoted CEC growth in vitro . By contrast,the growth of NOD2-deficient CECs was impaired. In vivo CEC proliferation was also reduced and apoptosis increased in Nod2-/- mice, which were also evident following enteric Salmonella infection. Furthermore, neutralization of NOD2 mRNA expression in human colonic carcinoma cells by shRNA interference resulted in decreased survival due to increased levels of apoptosis. CONCLUSION: These findings are consistent with the involvement of NOD2 protein in promoting CEC growth and survival. Defects in proliferation by CECs in cases of CD may contribute to the underlying pathology of disrupted intestinal homeostasis and excessive inflammation. | Sheena M Cruickshank Louise Wakenshaw John Cardone Peter D Howdle Peter J Murray Simon R Carding | 2008 | World Journal of Gastroenterology2008，14，38： | 3 |
| 3 | A Secure Key Management Scheme for Heterogeneous Secure Vehicular Communication Systems显示文摘Intelligent transportation system(ITS)is proposed as the most effective way to improve road safety and traffic efficiency.However,the future of ITS for large scale transportation infrastructures deployment highly depends on the security level of vehicular communication systems(VCS).Security applications in VCS are fulfilled through secured group broadcast.Therefore,secure key management schemes are considered as a critical research topic for network security.In this paper,we propose a framework for providing secure key management within heterogeneous network:The security managers(SMs)play a key role in the framework by retrieving the vehicle departure information,encapsulating block to transport keys and then executing rekeying to vehicles within the same security domain.The first part of this framework is a novel Group Key Management(GKM)scheme basing on leaving probability(LP)of vehicles to depart current VCS region.Vehicle's LP factor is introduced into GKM scheme to achieve a more efficient rekeying scheme and less rekeying costs.The second component of the framework using the blockchain concept to simplify the distributed key management in heterogeneous VCS domains.Extensive simulations and analysis are provided to show the effectiveness and efficiency of the proposed framework:Our GKM results demonstrate that probability-based BR reduces rekeying cost compared to the benchmark scheme,while the blockchain decreases the time cost of key transmission over heterogeneous networks. | LEI Ao Chibueze Ogah Philip Asuquo Haitham Cruickshank SUN Zhili | 2016 | ZTE Communications2016，14，B06： | 3 |
| 4 | Characterization of colonic dendritic cells in normal and colitic mice显示文摘AIM: Recent studies demonstrating the direct involvement of dendritic cells (DC) in the activation of pathogenic T cells in animal models of inflammatory bowel disease identify DC as important antigen presenting cells in the colon. However, very little is known about the properties of colonic DC.METHODS: Using immunohistochemistry, electron microscopy and flow cytometry we have characterized and compared colonic DC in the colon of healthy animals and interleukin-2-deficient (IL2-/-) mice that develop colitis.RESULTS: In the healthy colon, DC resided within the lamina propria and in close association with the basement membrane of colonic villi. Type 1 myeloid (CD11c+, CD11b+,B220-, CD8α-) DC made up the largest (40-45%) population and all DC expressed low levels of CD80, CD86, and CD40,and had high endocytic activity consistent with an immature phenotype. In colitic IL2-/- mice, colonic DC numbers increased four- to five-fold and were localized within the epithelial layer and within aggregates of T and B cells. They were also many more DC in mesenteric lymph nodes (MLN).The majority (>85%) of DC in the colon and MLN of IL2-/-mice were type 1 myeloid, and expressed high levels of MHC class Ⅱ, CD80, CD86, CD 40, DEC 205, and CCR5molecules and were of low endocytic activity consistent with mature DC.CONCLUSION: These findings demonstrate striking changes in the number, distribution and phenotype of DC in the inflamed colon. Their intimate association with lymphocytes in the colon and draining lymph nodes suggest that they may contribute directly to the ongoing inflammation in the colon. | Sheena M Cruickshank Nicholas R English Peter J Felsburg Simon R Carding | 2005 | World Journal of Gastroenterology2005，11，40： | 3 |
| 5 | 指南 成人原发及转移性脑肿瘤:NICE指南概要显示文摘原发恶性脑肿瘤虽然仅占癌症总数的3%,但其生存预后在所有癌症中却是最差的。尽管诊治水平有所改善,但恶性脑肿瘤的存活率依然很低(表1);人们认为通过制定全国统一实行的规范化指南,可延长患者寿命并改善生活质量。超过60%原发性脑肿瘤患者的初次诊断不是由全科医生或专科医生做出的,而是偶然发现的,或是在急诊就诊中发现的。在初级医疗中,最常见的脑肿瘤是脑转移瘤,当然也有其他类型脑肿瘤。 | Alex Bates Garth Cruickshank Tom Roques Guideline Committee 徐菲(译) 王燕(校) | 2018 | 英国医学杂志中文版2018，21，11： | 3 |
| 6 | The Wisconsin Epidemiologic Study of Diabetic Retinopathy. XV. The long-term incidence of macular edema显示文摘 | R. Klein B.E. Klein S.E. Moss K.J. Cruickshanks | 1995 | Ophthalmology1995，，1： | 3 |
| 7 | Heterogeneity across the murine small and large intestine显示文摘The small and large intestine of the gastrointestinal tract(GIT) have evolved to have discrete functions with distinct anatomies and immune cell composition.The importance of these differences is underlined when considering that different pathogens have uniquely adapted to live in each region of the gut.Furthermore,different regions of the GIT are also associated with differences in susceptibility to diseases such as cancer and chronic inflammation.The large and small intestine,given their anatomical and functional differences,should be seen as two separate immunological sites.However,this distinction is often ignored with findings from one area of the GIT being inappropriately extrapolated to the other.Focussing largely on the murine small and large intestine,this review addresses the literature relating to the immunology and biology of the two sites,drawing comparisons between them and clarifying similarities and differences.We also highlight the gaps in our understanding and where further research is needed. | Rowann Bowcutt Ruth Forman Maria Glymenaki Simon Richard Carding Kathryn Jane Else Sheena Margaret Cruickshank | 2014 | World Journal of Gastroenterology2014，20，41： | 2 |
| 8 | Video-rate image stabilization system显示文摘 | Maheux J Cruickshank J | 1998 | SPIE1998，3414，： | 2 |
| 9 | Role of interleukin-6 in mediating the acute-phase protein response and potential as an early means of severity in acute pancreatitis显示文摘 | Heach DJ Cruickshank A Gudgeon M | 1993 | Gut1993，34，1： | 1 |
| 10 | Fertlily and pregnancy outcome following large loop encision of the cervical transformation zone 显示文摘 | Cruickshank N E Flannelly G Canpbell D M | 1995 | Br Obstet Gynecal1995，102，6： | 1 |
| 11 | Management of high blood pressure in children and adolescents: recommendations of the European Society of Hypertension显示文摘 | Lurbe E Cifkova R Cruickshank J K | 2009 | J Hypertens2009，27，： | 1 |
| 12 | Tympano metric measures in older aduhs显示文摘 | Wiley TL Cruickshanks KJ Nondahl DM | 1996 | J Am Acad Audiol1996，7，： | 1 |
| 13 | Factors influencing over- anticoagulation and bleeding in warfarin therapy during the initial five months of treatment显示文摘 | Westaway K Cruickshank M Roberts GW | 2010 | Aust Nurs J2010，17，10： | 1 |
| 14 | Cryptococcus neoformans of unusual morphology显示文摘 | Cruickshank JG Cavill R Jelbert M | 1973 | Appl Microbiol1973，25，2： | 1 |
| 15 | Universal serial bus implementation in an integrated access chip for ISDN systems 显示文摘 | Cruickshank H Sun Z Fan Z | 2001 | IEEE Proc-Commun2001，，8： | 1 |
| 16 | Maternal protein intake in the pregnant rat programs the insulin axis and body composition in the offspring 显示文摘 | REES W D HAY S M CRUICKSHANK M | 2006 | Metabolism2006，55，5： | 1 |
| 17 | A challenge for (un)structural biology met by ion mobility-mass Spectrometry 显示文摘 | Jurneczko E Cruickshank F Porrini M | 2012 | Biochem Soc Trans2012，40，5： | 1 |
| 18 | A unified approach to dynamic length algo- rithms for adaptive linear equalizers显示文摘 | WEI Xusheng CRUICKSHANK D G M MULGREW B | 2007 | IEEE Transactions on Signal Processing2007，55，3： | 1 |
| 19 | Performance and modeling of a direct methanol fuel cell systems 显示文摘 | Scott K Tamma W Cruickshank | 1997 | Power sources1997，，65： | 1 |
| 20 | The adoption of e-trade innovations by Korean small and medium sized firms显示文摘 | OH K-Y CRUICKSHANK D ANDERSON A R | 2009 | Technovation2009，29，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员