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660篇 您的检索式:作者名="Crookes R"
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1Role of myeloid-derived suppressor cells in autoimmune disease显示文摘Myeloid-derived suppressor cells(MDSCs) represent an important class of immunoregulatory cells that can be activated to suppress T cell functions. These MDSCs can inhibit T cell functions through cell surface interactions and the release of soluble mediators. MDSCs accumulate in the inflamed tissues and lymphoid organs of patients with autoimmune diseases. Much of our knowledge of MDSC function has come from studies involving cancer models, however many recent studies have helped to characterize MDSC involvement in autoimmune diseases. MDSCs are a heterogeneous group of immature myeloid cells with a number of different functions for the suppression of T cell responses. However, we have yet to fully understand their contributions to the development and regulation of autoimmune diseases. A number of studies have described beneficial functions of MDSCs during autoimmune diseases, and thus there appears to be a potential role for MDSCs in the treatment of these diseases. Nevertheless, many questions remain as to the activation, differentiation, and inhibitory functions of MDSCs. This review aims to summarize our current knowledge of MDSC subsets and suppressive functions in tissue-specific autoimmune disorders. We also describe the potential of MDSC-basedcell therapy for the treatment of autoimmune diseases and note some of hurdles facing the implementation of this therapy.Kristen R Crook Peng Liu 2014World Journal of Immunology2014,4,1:9
2Motivation: Reopening the research agenda 显示文摘Crookes G & Schmidt R 1991Language Learning1991,,41:1
3Relative sensitivies of mammalian carnivores to habitat fragmentation显示文摘CROOKS K R 2002Conservation Biology2002,16,2:1
4The potential of dimethyl ether(DME) as an alternative fuel for compression-ignition engines:a review显示文摘Arocumanis C Bae C Crookes R 2008Fuel2008,87,7:1
5An apoptosis-inhibiting bac ulovirus gene with a zinc finger-like motif显示文摘 Clem R J Miller L K 1993J Virol1993,67,4:1
6Loss of interferon regulatory factor 3 in cells infected with classical swine fever virus involves the N-terminal prote- ase, Nvr' 显示文摘LA ROCCA S A HERBERT R J CROOKE H 2005Journal of Virology2005,79,11:1
7Trace element characteristics of greywackes and tectonic setting discrimination of sedimentary basins显示文摘BHATIA M R and CROOK K A W 1986Contrib Mineral Petrol1986,92,:1
8Trace element characteristics of grey- wacke and tectonic setting discrimination of sedimentary basins 显示文摘Bhatia M R Crook K A W 1986Contributions to Mineralogy and Petrology1986,92,2:1
9Buyer power and supplier incentives显示文摘Crook T R Combs J G 2005Europe- an Economic Review2005,51,3:1
10Wireless electrochemical DNA microarray sensor显示文摘Chow K F Mavre F 0 Crooks R M 2008Journal of the American Chemical Society2008,130,24:1
11Real-time measurements of the gas-phase adsorption of n-alkyhhiol mono- and muhilayers on gold显示文摘THOMOS R C SUN L CROOKS R M 1991Langmuir1991,7,:1
12Nuclear magnetic resonance imaging显示文摘Crooks L Herfkens R Kaufman L 1981Prog Nucl Med1981,7,:1
13Glutathion depletion as a determinant of sensitivity human of leukemia cells to cyclophosphamide显示文摘Crook T R 1996Cancer Res1996,46,:1
14Trace element characteristics of graywackes and tectonic setting discrimination of sedimentary basins显示文摘Bhatia M R Crook K A W 1986Contributions to Mineralogy and Petrology1986,92,:1
15Semi-empirical approach to optimise the quantity of drying aids required to spray dry sugar-rich foods显示文摘Bhandari BR Datta N Crook R 1997Dry Technology1997,15,10:1
16Preparation and characterization of dendrimer-encapsulated CdS semiconductor quantum dots 显示文摘Lemon B I Crooks R M 2000Journal of the American Chemical Society2000,122,12:1
17Molecules in focus Leukotriene B4 显示文摘Crooks S W Stockley R A 1998Int J Bio-chem Cell Biol1998,30,:1
18Studies on uptake of heavy metals by the Scandinavian 'kisplanten' Lychnis alpina and Silene dioica显示文摘Brooks R R Crooks H M 1980Plant and Soil1980,54,:1
19Weathering of the balustrade on St Paul' s Cathedral, London 显示文摘Sharp A D Trudgill S T Crooke R U 1982Earth Surface Processes and Landforms1982,7,:1
20Trace element characteristics of graywackes and tectonic setting discrimination of sedimentary basin 显示文摘BHATIA M R CROOK A W 1986Contributions to Mineralogy and Petrology1986,92,:1
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