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| 1 | Celiac disease serology in patients with different pretest probabilities: Is biopsy avoidable?显示文摘AIM: To establish the diagnostic performance of sev-eral serological tests, individually and in combination, for diagnosing celiac disease (CD) in patients with different pretest probabilities, and to explore potential se- rological algorithms to reduce the necessity for biopsy. METHODS: We prospectively performed duodenal biopsy and serology in 679 adults who had either high risk (n = 161) or low risk (n = 518) for CD. Blood samples were tested using six assays (enzyme-linked immunosorbent assay) that detected antibodies to tissue transglutaminase (tTG) and deamidated gliadin peptide (DGP). RESULTS: CD prevalence was 39.1% in the high-risk population and 3.3% in the low-risk group. In high-risk patients, all individual assays had a high diagnostic efficacy [area under receiving operator characteristic curves (AU ROC): 0.968 to 0.999]. In contrast, assays had a lower diagnostic efficacy (AU ROC: 0.835 to 0.972) in the low-risk group. Using assay combinations, it would be possible to reach or rule out diagnosis of CD without biopsy in 92% of cases in both pretest populations. We observed that the new DGP/tTG Screen assay resulted in a surplus compared to more conventional assays in any clinical situation. CONCLUSION: The DGP/tTG Screen assay could be considered as the best initial test for CD. Combinations of two tests, including a DGP/tTG Screen, might be able to diagnose CD accurately in different clinical scenarios making biopsy avoidable in a high proportion of subjects. | Emilia Sugai María L Moreno Hui J Hwang Ana Cabanne Adriana Crivelli Fabio Nach-man Horacio Vázquez Sonia Niveloni Julio Argonz Roberto Mazure Graciela La Motta María E Caniggia Edgardo Smecuol Néstor Chopita Juan C Gómez Eduardo Maurińo Julio C Bai | 2010 | World Journal of Gastroenterology2010，16，25： | 4 |
| 2 | Influence of osmosis time on the quality of dehydrofrozen kiwi fruit 显示文摘 | Forni E Torregiani D Crivelli G | 1990 | Acta Horticuhurae Sinica1990，282，： | 1 |
| 3 | Influence of osmosis time on the quality of dehydrofrozen kiwi fruit显示文摘 | FORNI E TORREGIANI D CRIVELLI G | 1990 | Acta Horticulturae Sinica1990，，282： | 1 |
| 4 | Hysterosalpingography in infertility investigation protocol: is it still useful? 显示文摘 | Capobianco G Crivelli P Piredda N | 2015 | Clin Exp Obstet Gynecol2015，42，4： | 1 |
| 5 | Risk of fracture in celiac disease:Gender,dietary compliance,or both?显示文摘AIM:To determine the incidence of peripheral fractures in patients with celiac disease (CD) and the effect of treatment on fracture risk.METHODS:We compared the incidence and risk of peripheral fractures before and after diagnosis between a cohort of 265 patients who had been diagnosed with CD at least 5 years before study entry and a cohort of 530 age-and sex-matched controls who had been diagnosed with functional gastrointestinal disorders.Data were collected through in-person interviews with an investigator.The overall assessment window for patients was 9843 patient-years (2815 patient-years after diagnosis).RESULTS:Compared with the control group,the CD cohort showed significantly higher incidence rate and risk of first peripheral fracture before diagnosis [adjusted hazard ratio (HR):1.78,95% CI:1.23-2.56,P < 0.002] and in men (HR:2.67,95% CI:1.37-5.22,P < 0.004).Fracture risk was significantly associated with the classic CD presentation with gastrointestinal symptoms (P < 0.003).In the time period after diagnosis,the risk of fractures was comparable between the CD cohort and controls in both sexes (HR:1.08,95% CI:0.55-2.10 for women;HR:1.57,95% CI:0.57-4.26 for men).CONCLUSION:CD patients have higher prevalence of fractures in the peripheral skeleton before diagnosis.This is associated with male sex and classic clinical presentation.The fracture risk was reduced after the treatment. | María Inés Pinto Sánchez Adriana Mohaidle Andrea Baistrocchi Dolores Matoso Horacio Vázquez Andrea González Roberto Mazure Evangelina Maffei Guillermina Ferrari Edgardo Smecuol Adriana Crivelli Juan Andrés de Paula Juan C Gómez Silvia Pedreira Eduardo Maurio Julio César Bai | 2011 | World Journal of Gastroenterology2011，17，25： | 1 |
| 6 | Hysterosalpingogra- phy in infertility investigation protocol is it still useful? 显示文摘 | Capobianco G Crivelli P Piredda N | 2015 | Clin Exp Obstet Gynecol2015，42，4： | 1 |
| 7 | Influence of osmosis time on the quality of dehydrofrozen kiwi fruit 显示文摘 | Forni E Torregiani D Crivelli G | 1990 | Acta Horticulturae Sinica1990，282，： | 1 |
| 8 | Biological compost stability influences odor molecules production measured by electronic nose during food-waste high-rate composting 显示文摘 | D'Imporzano G Crivelli F Adani F | 2008 | Science of the total environment2008，402，23： | 1 |
| 9 | Treatment and long-term follow-up results of prolactin secreting pituitary adenomas 显示文摘 | Scamoni C Balzarini C Crivelli G | 1991 | J Neurosurg Sci1991，35，1： | 1 |
| 10 | Biological compost stability influences odor molecules production measured by electronic nose during food-waste high-rate composting显示文摘 | D'Imporzano G Crivelli F Adani F | 2008 | Science of the Total Environment2008，402，23： | 1 |
| 11 | Hysterosalpingographyin infertility investigation protocol: is it still useful? 显示文摘 | Capobianco G Crivelli P Piredda N | 2015 | Clin ExpObstet Gynecol2015，42，4： | 1 |
| 12 | Third ventricle cavernoma associated with venous angioma显示文摘 | Crivelli G Dario A Cerati M | 2002 | J Neurosurg Sci2002，46，34： | 1 |
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