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您的检索式：作者名="Cristina Modak"
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| 1 | Serum response factor:Look into the gut显示文摘Serum response factor(SRF) is a transcription factor that regulates many genes involved in cellular activities such as proliferation,migration,differentiation,angiogenesis,and apoptosis.Although it has only been known for about two decades,SRF has been studied extensively.To date,over a thousand SRF studies have been published,but it still remains a hot topic.Due to its critical role in mesoderm-derived tissues,most of the SRF studies focused on muscle structure/function,cardiovascular development/maintenance,and smooth muscle generation/repair.Recently,SRF has received more attention in the digestive field and several important discoveries have been made.This review will summarize what we have learned about SRF in the gastrointestinal tract and provide insights into possible future directions in this area. | Cristina Modak | 2010 | World Journal of Gastroenterology2010，16，18： | 3 |
| 2 | Potential of casein kinase I in digestive cancer screening显示文摘Casein kinase I is a group of ubiquitous Serine/Threonine kinases that have been implicated in both normal cellular functions and several pathological conditions including Alzheimer's disease and cancer.Recent findings in colon and pancreatic cancer have brought tremendous attention to these molecules as potential therapeutic targets in treatment of digestive cancers.In this review,we summarize up to date what is known about this family of kinases and their involvement in carcinogenesis and other pathological conditions.Our emphasis is on their implications in digestive cancers and their potential for cancer screening and therapy. | Cristina Modak Jianyuan Chai | 2009 | World Journal of Gastrointestinal Oncology2009，1，1： | 1 |
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