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95篇 您的检索式:作者名="Covacci A"
    题名 作者 年代 出处 被引量
1幽门螺杆菌与胃癌的关系显示文摘本文报道1994年在福建长乐进行的大规模胃癌防治计划,通过胃镜、血液检查及问卷检查,发现30例胃癌及214例消化性溃疡,幽门螺杆菌的感染率在各类人群中为67%至94%不等。在年龄36岁至65岁组中,长乐地区幽门螺杆菌的感染率明显高于香港,无论是幽门螺杆菌的感染者或非感染者,胃窦肠上皮化生发现率在长乐都高于香港,在长乐,胃窦肠上皮化生发现率高于胃体肠上皮化生。长乐及香港的Cag-A阳性菌株与各种胃疾病有明显关系,在无症状组中,Cag-A阳性菌株在长乐占72%,明显高于香港的29%。Cag-A阳性菌株与胃炎、粘膜萎缩、肠上皮化生、不典型增生和胃癌有明显关系。问卷发现多喝茶及多进食蔬菜有保护作用,而抽烟及饮酒人群或进食咸鱼有较多机会形成胃癌。王振宇 林兆鑫 高震 陈建顺 胡兴正 程自刚 黎锦泉 何楚盈 袁兆灿 陈宝雯 王蔚虹 陈君石 候晓华 姜希望 卢家扬 A Covacci 1997胃肠病学1997,2,3:3
2Induction of host signal transduction pathways by Helicobacter pylori 显示文摘Segal ED Lange C Covacci A 1997Proc Natl Acad Sci USA1997,94,:1
3Proteins encoded by the cag pathogenicity island of Helicobacter pylori are required for NF-κB activation 显示文摘Glocker E Lange C Covacci A 1998Infect Immu1998,66,:1
4The design of vaccines against Helicobacter pylori and their development 显示文摘Del Giudice G Covacci A Telford JL 2001Annu Rev Immunol2001,19,:1
5Did the inheritance of a pathogenicity island modify the virulence of Helicobacter pylori显示文摘Covacci A Falknow S Berg DE 1997Trends Microbiol1997,5,:1
6Helicobacter pylori activates mitogen-activated protein kinase cascades and induces expression of the proto-oncogenes c-fos and c-jun显示文摘Meyer-ter-Vehn T Covacci A Kist M 2000J Biol Chem2000,275,16:1
7Unravelling the pathogenic role of Helieobacter pylori in peptic ulcer: potential new therapies and vaccines显示文摘Telford J L Covacci A GhJara P et aI 1994Trends Biotechnol1994,12,10:1
8The design of vaccines against Helicobacter pylori and their development 显示文摘Del Giudice G Covacci A Telford JL 2001Annu Rev Immunol2001,19,:1
9Induction of host signal transduction pathways by Helicobaeter pylori显示文摘Segal ED Lange C Covacci A 1997Proc Natl Acad Sci USA1997,94,14:1
10Helicobacter pyl ori induced interleukin-8 expression in gastric epithelial cells is associated with CagA positive phenotyp e显示文摘 Covacci A Farmery SM 1995J Clin Pathol1995,48,:1
11Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag-driven host cell translocation显示文摘Stein M Rappuoli R Covacci A 2000Proc Natl Acad Sci USA2000,97,3:1
12Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cagA-driven host cell translocation 显示文摘STEIN M RAPPUOLI R COVACCI A 2000Proc Natl Aead Sei2000,97,3:1
13Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA显示文摘Amieva M R Vogelmann R Covacci A 2003Science2003,300,5624:1
14Helicobacter pylori virulence and genetic geography显示文摘Covacci A Telford J L Del Giudice G 1999Science1999,,284:1
15Disruption of the epithelial apicaljunctional complex by Helicobacter pylori CagA显示文摘AMIEVA M R VOGELMANN R COVACCI A 2003Science2003,300,5624:1
16Reverse vaccinology and genomics显示文摘Rappuoli R Covacci A 2003Science2003,302,5645:1
17Cellular responses induced after contact with Helicobacter pylori显示文摘 Stein M Covacci A 2001Current Opinion in Microbiology2001,4,:1
18Molecular characterization of the128-kDa immunodominant antigen of helieobaeter pylori associated with cytotoxicity and duodenal ulcer显示文摘Covacci A Censini S Bugnoli M 1993Proc Nat] Aead Sci USA1993,90,12:1
19Mutant of pertussis toxin suitble for vaccine development 显示文摘PIZZA M COVACCI A BARTOLONI A 1989Science1989,246,4929:1
20Helicobacter pylori virulence and genetic geography显示文摘Covacci A Telford JL Del Giudice G 1999Science1999,284,5418:1
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