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| 1 | Role of sex hormones in gastrointestinal motility in pregnant and non-pregnant rats显示文摘AIM: To correlate gastric contractility, gastrointestinal transit, and hormone levels in non-pregnant(estrous cycle) and pregnant rats using noninvasive techniques. METHODS: Female rats(n = 23) were randomly divided into(1) non-pregnant,(contractility, n =6; transit, n = 6); and(2) pregnant(contractility, n = 5; transit, n = 6). In each estrous cycle phase or at 0, 7, 14, and 20 d after the confirmation of pregnancy, gastrointestinal transit was recorded by AC biosusceptometry(ACB), and gastric contractility was recorded by ACB and electromyography. After each recording, blood samples were obtained for progesterone and estradiol determination. RESULTS: In the estrous cycle, despite fluctuations of sex hormone levels, no significant changes in gastrointestinal motility were observed. Days 7 and 14 of pregnancy were characterized by significant changes in the frequency of contractions(3.90 ± 0.42 cpm and 3.60 ± 0.36 cpm vs 4.33 ± 0.25 cpm) and gastric emptying(168 ± 17 min and 165 ± 15 min vs 113 ± 15 min) compared with day 0. On these same days, progesterone levels significantly increased compared with control(54.23 ± 15.14 ng/m L and 129.96 ± 30.52 ng/mL vs 13.25 ± 6.31 ng/mL). On day 14, we observed the highest level of progesterone and the lowest level of estradiol compared with day 0(44.3 ± 15.18 pg/mL vs 24.96 ± 5.96 pg/mL). CONCLUSION: Gastrointestinal motility was unaffected by the estrous cycle. In our data, high progesterone and low estradiol levels can be associated with decreased contraction frequency and slow gastric emptying. | Juliana Fernandes Matos Madileine Francely Americo Yuri Karen Sinzato Gustavo Tadeu Volpato Luciana Aparecida Corá Marcos Felipe Freitas Calabresi Ricardo Brandt Oliveira Debora Cristina Damasceno Jose Ricardo Arruda Miranda | 2016 | World Journal of Gastroenterology2016，22，25： | 5 |
| 2 | A CRISPR screen identifies CDK7 as a therapeutic target in hepatocellular carcinoma显示文摘 | Cun Wang Haojie Jin Dongmei Gao Liqin Wang Bastiaan Evers Zheng Xue Guangzhi Jin Cor Lieftink Roderick L. Beijersbergen Wenxin Qin Rene Bernards | 2018 | Cell Research2018，28，6： | 4 |
| 3 | Gene-modified T cells for adoptive immunotherapy of renal cell cancer maintain transgene-specific immune functions in vivo显示文摘 | Cor H. J. Lamers Sabine C. L. Langeveld Corrien M. Groot-van Ruijven Reno Debets Stefan Sleijfer Jan Willem Gratama | | Cancer Immunology Immunotherapy0，，： | 2 |
| 4 | 气固流态化动态特征的模拟(英文)显示文摘运用基于硬球理论的离散型模型模拟了气固流态化的基本特征,观察了操作条件对鼓泡流化的影响.其模拟结果表明:1.气体通过分布板后形成许多气泡.最初,这些气泡以较小的尺寸形成在孔口,然后逐渐长大并上升.当气泡到达床层表面而破裂时,导致了床层表面的波动.2.床层中的压降随着气体速度和气体分布板中孔数的增加而增加.从而增加气体速度和分布板孔数将产生更多的气泡,并改进颗粒间的混合程度.3.与国际上现有离散型模型相比,基于颗粒运动分解思想的硬球模型更为真实、更为简单.它能够定性而形象地复现气固流化系统的实验特征,为实验预测提供辅助的研究方法. | 欧阳洁 李静海 孙国刚 Cor M.var den Bleek | 2002 | 应用基础与工程科学学报2002，10，4： | 2 |
| 5 | The use of perfusion CT for the evaluation of therapy combining AZD2171 with gefitinib in cancer patients显示文摘 | Martijn R. Meijerink Hester Cruijsen Klaas Hoekman Matthijs Kater Cors Schaik Jan Hein T. M. Waesberghe Giuseppe Giaccone Radu A. Manoliu | 2007 | European Radiology2007，，7： | 2 |
| 6 | Analysis of asphalt mix surface-tread rubber interaction by using finite element method显示文摘The surface texture of the pavement plays a very important role in driving the frictional properties at the tire rubber-pavement interface. Particularly, the hysteretic friction due to viscoelastic deformations of rubber depends mainly on the pavement surface texture. In the present paper, the effect of micromechanical pavement surface morphology on rubber block friction was brought in by comparing the friction results for three different asphalt mix morphological surfaces, named stone mastic asphalt(SMA), ultra-thin surfacing(UTS) and porous asphalt(PA). The asphalt surface morphologies of these mixes were captured by using an X-ray tomographer, from which the resulting images micromechanical finite element(FE) meshes for SMA, UTS and PA pavements were developed by means of the SimpleWare software. In the FE model, the rubber and asphalt binder were modeled as viscoelastic(VE) materials and the formulation was given in the large deformation framework. FE simulations were then carried out by using contact algorithm between rubber and the road surface. It was observed that the rubber friction inversely varies with the sliding speed and positively varies with the pressure for all the pavement morphological and stiffness conditions. Furthermore, it was observed that the highly porous pavement surface results in large dissipation of energy, hence, large rubber friction which shows that the mix characteristics of pavements have a significant effect on rubber friction. | Santosh Kumar Srirangam Kumar Anupam Cor Kasbergen Athanasios (Tom) Scarpas | 2017 | Journal of Traffic and Transportation Engineering(English Edition)2017，4，4： | 2 |
| 7 | Prognostic significance of apoptosis in medulloblastoma显示文摘 | Pizem J Cor A Zadravec Zaletel L | 2005 | Neurosci Lett2005，381，12： | 1 |
| 8 | Simultaneous quantifi- cation of free nucleotides in complex biological samples using ion pair reversed phase liquid chromatography isotope dilution tandem mass spectrometry 显示文摘 | Reza MS Cor R Jan C van Dam | 2009 | Analytical Biochemistry2009，388，2： | 1 |
| 9 | In progressive nephropathies,overload of tubular cells with filtered proteins translates glomerular permeability dysfunction into cellular signals of interstitial inflammation显示文摘 | ZOJ C COR D | 1998 | J Am Soc Nephrol1998，9，： | 1 |
| 10 | The adaptation of digestive enzymes to the diet:its physiological significance显示文摘 | CORRING T | 1980 | Reproduction Nutrition Development1980，20，： | 1 |
| 11 | Ripening and quality responses of avocado,custard apple,mango and papaya fruit to 1-methylcyclopropene显示文摘 | Hofman P J Jobin-Décor M Meiburg G F | 2001 | Australian Journal of Experimental Agriculture2001，41，4： | 1 |
| 12 | Phasar-based WDM-devices:principles, design and applications 显示文摘 | Meint K Smit Cor Van Dam | 1996 | IEEE Journal of Selected Topics in Quantum Electronics1996，2，2： | 1 |
| 13 | Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis显示文摘 | DEN M COR P | 2000 | J Am Soc Nephrol2000，11，： | 1 |
| 14 | On the finks between attachment style,parental rearing behaviors and internalizing and externalizing problems in non-clinical children显示文摘 | Jeffrey R Cor M Mijke TH | 2006 | Journal of Child and Family Studies2006，15，3： | 1 |
| 15 | Screening and confirmatory determination of ractopamine residues in calvestreated with growth promoting doses of the β -agonist显示文摘 | Christopher T E Colin S T Cor J A | 1998 | Analyst1998，123，： | 1 |
| 16 | Three natural zircon standards for U-Th-Pb, Lu-Hf, tree element and REE analy- ses显示文摘 | Wiedenbeck M A Cor{u F | 1995 | Geostandard Newsletter1995，19，： | 1 |
| 17 | Structure and chemical kinetics of flames supported by solid propellant combustion 显示文摘 | Cor J J Branch M R | 1995 | Journal of Propulsion and Power1995，11，4： | 1 |
| 18 | A preliminary molecular analysis of phylogenetic relationships of Australasian wolf spider genera (Araneae,Lycosidae)显示文摘 | Anthony D Mitchell and Adrian M Paterson | 2002 | J Arachnology2002，30，： | 1 |
| 19 | Corporate Environmental Disclosure:ContrastingManagement’s Perceptions with Reality显示文摘 | Cor m ier D I M Gordon M Ma g n a n | 2004 | Journalof Business Ethics2004，49，2： | 1 |
| 20 | Gender - role stereotypes and terpersonal behavior,how addicted inpatients view their ideal male and female therapist 显示文摘 | Jonker J Cor A Jong JD | 2000 | Journal of Substance Abuse Treatment2000，19，3： | 1 |
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