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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | FTIR spectroscopic analysis of coals and coal extracts显示文摘 | COOKE N E FULLER M O GAIKWARD R P | 1986 | Fuel1986，65，9： | 2 |
| 3 | Examination of the melatonin hypothesis in women exposed at night to EMF or bright light显示文摘 | GRAHAM C COOK M R GERKOVICH M M | 2001 | Environ Health Perspect2001，109，5： | 1 |
| 4 | Fibroblast growth factor, epidermal growth factor, and platelet derived growth factor-BB stimulate proliferation of clonally derived porcine myogenic satellite cells显示文摘 | Doumit M E Cook D R Merkel R A | 1993 | J Cell Physiol1993，157，： | 1 |
| 5 | Diurnal variations in hydraulic conductivity and root pressure can be correlated with the expression of putative aquaporlns in the roots of Lotus japonicus显示文摘 | HENZLER T WATERHOUSE R N SMYTH A J CARVAJAL M COOKE D T SCHAFFNER A R STEUDLE E CLARKSOND T | 1999 | Planta1999，210，： | 1 |
| 6 | Arthroscopic verification of ultrasonographic diagnosis of meniscal pathology in dogs显示文摘 | Mahn M M Cook J L Cook C R | 2005 | Vet Surg2005，34，4： | 1 |
| 7 | Analysis of freeway traffic time- series data by using Box-Jenkins technique 显示文摘 | Ahmaed M S Cook A R | 1979 | Trans- portation Research Board1979，，722： | 1 |
| 8 | Effects of T-2 mycotoxin on gastrointestinal tissues : a review of in vivo and in vitro models 显示文摘 | WORRELL N R MALLETT A K COOK W M | 1989 | Environ Toxicol1989，18，1： | 1 |
| 9 | The Distribution of Power in Exchange Networks:Theory and Experimental Results显示文摘 | Cook Karen S Richard M Emerson Mary R Gillmore | 1983 | American Journal of Sociology1983，89，2： | 1 |
| 10 | Construction and testing of micmsatellite database containing more than 500 tomoto varieties 显示文摘 | BREDEMEIJER G M M COOK R J GANAL M W | 2002 | Theor Appl Genet2002，105，： | 1 |
| 11 | A comparison of clustering dynamics in the british broadcasting and financial services industries显示文摘 | NARESH R PANDIT GARY A S COOK G M P SWANN | 2002 | Economics of Business2002，9，2： | 1 |
| 12 | Assessment of the uniformity of wheat and tomato varieties at DNA microsatel- lite loci 显示文摘 | Cooke R J Bredemeijer G M M Ganal M W el al | 2003 | 132 : 33 ! -3412003，132，： | 1 |
| 13 | The dynamics of industrial clustering in British Financial Services 显示文摘 | Pandit N R Cook G Swarm P G M | 2001 | The Service Indus- tries Journal2001，21，4： | 1 |
| 14 | Prediction of headcut migration using a deterministic approach 显示文摘 | HANSON G J ROBINSON K M COOK K R | 2001 | Transactions of the ASAE2001，44，3： | 1 |
| 15 | Toxic equivalency factors of polychlorinated dibenzo-p-dioxin, dibenzofuran and biphenyl congeners based on early life stage mortality in rainbow trout ( Oncorhynchus mykiss) 显示文摘 | Zabel E W Cook P M Peterson R E | 1995 | Aquatic Toxicology1995，31，： | 1 |
| 16 | The Dynamics of Industrial Clustering in British Financial Services 显示文摘 | Pandit N R Cook G A S Swann G M P | 2001 | The Service Industrial Journal2001，21，4： | 1 |
| 17 | The dynamics of industrial clustering in British broadcasting显示文摘 | Cook A S G Pandit N R Swann G M P | 2001 | Information Economics and Policy2001，13，3： | 1 |
| 18 | Birkhead revised:petrological and geochemical studies of the Birkhead formation, Eromanga Basin显示文摘 | Smyth M Cook A C Philp R P | 1984 | APEA1984，24，1： | 1 |
| 19 | Behavior of rock during blasting显示文摘 | Cook M A Cook U D Clay R B | | 0，，02： | 1 |
| 20 | Endoscopic partial inferior turbinoplasty显示文摘 | DELDEN M R COOK P R DAVIS W E | 1999 | Otolaryngol Head Neck Surg1999，121，： | 1 |
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