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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | 相对于男性,女性进行冠状动脉造影产生的额外的心血管病风险与严重受损的冠状动脉血流储备,而非阻塞性疾病相关显示文摘与男性相比,女性的心血管病死亡率更高,但是阻塞性冠状动脉疾病(coronary artery disease,CAD)在女性中不太普遍。冠状动脉血流储备(coronary flow reserve,CFR)是大、小血管CAD和心肌缺血的综合测量指标,可识别出具有心血管病死亡风险的患者,但其在临床实践中不是常规测量的指标。该研究试图调查性别、CFR和血管造影CAD严重程度对不良心血管事件的影响。 | 刘莉 叶鹏 Taqueti VR Shaw LJ Cook NR Murthy VL Shah NR Foster CR Hainer J Blankstein R Dorbala S Di Carli MF | 2016 | 中华高血压杂志2016，24，11： | 2 |
| 3 | Short term evaluation of carbon coated and uncoated porous titanium implants clin显示文摘 | COOK S D HADDAD R J | 1989 | Clin Mater1989，4，： | 1 |
| 4 | Nitric oxide regula- tion of gonadotrophin seeretion in prepubertal heifers显示文摘 | Honaramooz A Cook S J Beard A P et ol | 1999 | J Neu- roendoerinol1999，11，9： | 1 |
| 5 | Recognizing speech under a processing load:Dissociatting energetic from informational factors显示文摘 | Mattys S L Brooks J Cooke M | | 0，，03： | 1 |
| 6 | Results of the pilot studyfor the Hypertension in the Very Elderly Trial显示文摘 | Bulpitt C J Beckett N S Cooke J | 2003 | J Hypertens2003，21，12： | 1 |
| 7 | Fractionation of polyethylene显示文摘 | FRSNCIS P S COOKE R C Jr ELLIOTT J H | 1958 | J Polym Sci1958，31，123： | 1 |
| 8 | Acceleration of tibia and distal radius fracture healing in patients who smoke显示文摘 | Cook S D Ryaby J P McCabe J | 1997 | Clin Orthop Relat Res1997，337，： | 1 |
| 9 | Linear theory of a wide-band Gyro-TWT amplifier using spiral waveguide 显示文摘 | COOKE S J DENISOV G G | 1998 | IEEE Transactions on Plasma Science1998，26，3： | 1 |
| 10 | ^99mTc-HL91 to identify tumor hypoxia:Correlation with 18F-FDG显示文摘 | Cook G J Houston S Barrington S F | 1998 | J Nucl Med1998，39，1： | 1 |
| 11 | The clinical signifcance of serum transferring receptor levels in sickle cell disease显示文摘 | Singhal A Cook J D Sikne B S | 1993 | Br J Haematol1993，84，： | 1 |
| 12 | Simultaneous axial and rotational electron beam velocity measurement using a phosphor scintillator显示文摘 | He W Cooke S J Cross A W | 2001 | Review of Scientific Instruments2001，72，5： | 1 |
| 13 | Atmospheric Corrosion of Different Steels in Marine, Rural and Industrial Environments 显示文摘 | Oh S J Cook D C Townsend H E | 1999 | Corrosion Science1999，41，3： | 1 |
| 14 | Mechanism of friction in rotating carbon nanotube bearings 显示文摘 | Cook E H Buehler M J Spakovszky Z S | 2013 | Journal of the Mechanics and Physics of Solids2013，61，2： | 1 |
| 15 | Incidence of and risk factors for ventilator-associated pneumonia in critically ill patients显示文摘 | Cook D J Walter S D Cook R J | | 0，，06： | 1 |
| 16 | Relative roles of the epithelial and stromal tissue compartment ( s ) in mediating the actions of relaxin and estrogen on cell proliferation and apoptosis in the mouse lower reproductive traet显示文摘 | Yao L J Agoulnik A I CooKe P S | 2009 | Ann N Y Acad Sci2009，11，11： | 1 |
| 17 | Lipid modulation of Plasina mem- branebound ATPase 显示文摘 | Cooke D J Burden R S | 1990 | Plant Physiology1990，78，1： | 1 |
| 18 | Rapid sea level rise and Holocene climate in the Chukchi sea显示文摘 | Keigwin L D Donnell J P Cook M S | 2006 | Geology2006，34，10： | 1 |
| 19 | Envelope determinants of equine infectious anemia virus vaccine protection and the effects of sequence variation on immune recognition显示文摘 | Tagmyer T L Craigo J K Cook S J | 2008 | J Virol2008，82，8： | 1 |
| 20 | A review of postural orthostatic tachycardia syndrome显示文摘 | Carew S Connor MO Cooke J | 2009 | Europace2009，11，1： | 1 |
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