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| 1 | Relationship between skin fold thickness and insulin resistance in the essential hypertensive patients in Vietnam显示文摘Previous studies reported a close relationship between obesity and insulin resistance in the essential hypertensive patients. Objective In this study, we examined the relationship between the skin fold thickness and insulin resistance then developed a formula to estimate the insulin resistance index according to the skin fold thickness in the essential hypertensive patients. Subjects and Methods Medical records of 80 patients (37 males, 43 females) were reviewed and the data were tabulated. Anthropometric indexes (including height, weight, waist circumference, hip circumference, and skins fold thickness at 5 fatty difference points on the Erdheim diagram), fasting plasma glucose and insulin concentration were recorded. The mean age was 57.0±9.2 years. The insulin resistance index was calculated following the Homeostasis Model Assessment (HOMA) formula. Results Compared with the group with BMI<23kg/m2, the group with BMI≥23 kg/m2 had higher fasting insulin concentration (8.85 ± 4.97 pmol/L vs 15.60 ± 8.70 pmol/L, P<0.001 ) and higher insulin resistance index in (2.15±1,24 vs 3.76±2.22, P<0.001). No significant difference in fasting plasma insulin concentration,insulin resistance index between male and female was observed (P>0.05). There was a positive correlation between skin fold thickness and the fasting insulin concentration and insulin resistance index. The skin fold thickness at point A8 had the best coefficient correlated with fasting plasma insulin(r=0.79, P<0.001) and insulin resistance index (r= 0.79, P < 0.001). A formula to estimate the insulin resistance index by skin fold thickness at point A8 as: Insulin resistance index = 0.12 × [skin fold thickness at A8 point (mm)] - 1.Conclusion: In the essential hypertensive patients, the formula to estimate insulin resistance index as 0.12 × [skin fold thickness at A8 point (mm)]-1 may predict accurately the level of insulin resistance. | Toan C Nguyen Khoa TA Pham Quyen TL Do Cuong T Nguyen Diep D Nguyen Vinh G Le Cong D Nguyen | 2005 | Journal of Geriatric Cardiology2005，2，4： | 4 |
| 2 | Folate and vitamin B12 in idiopathic male infertility显示文摘尽管 methylenetetrahydrofolate reductase,叶酸的酶基因,与自发的男不孕被联系了,很少研究检验了另外的叶酸相关的代谢物和基因。我们调查了自发的男不孕是否与变体被联系在叶酸,维生素 B 12(B12 ) 和全部的 homocysteine (tHcy ) 联系了基因并且在血测量了这些代谢物。我们进行了与自发的不孕和在生育力中心和胎儿的照顾中心招募的 184 肥沃的男控制包括了 153 个人的盒子控制研究,大学医院, Malmö并且 Lund,瑞典。浆液叶酸的、红房间叶酸(RCF ) ,浆液 B12,血浆 tHcy 和精液质量被测量。题目是为在与 folate/B12/homocysteine 新陈代谢有关的 12 基因的 20 普通变体的 genotyped。代谢物集中和遗传型分布为 covariates 与调整用线性、逻辑的回归在案例和控制之间被作比较。phosphatidylethanolamine N-methyltransferase (PEMT ) M175V 和 TCblR rs173665 多型性显著地与不孕被联系(P=0.01 和 P=0.009,分别地) ,然而并非与精液质量。在补充的非用户之中,有的不肥沃的人降低浆液叶酸的集中比肥沃的人(12.89 对 14.73 nmol l −1 ;P=0.02 ) ,但是在 RCF, B12 或 tHcy 没有重要差别。叶酸, B12 和 tHcy 集中没与任何精液参数被相关。这研究几乎不提供小支持为低叶酸或在自发的男不孕的致病的 B12 地位。尽管另外的数据被需要证实这些起始的调查结果,我们的结果建议那 PEMT 和 TCblR,基因在胆碱和 B12 新陈代谢包含了,在自发的男不孕应得进一步的调查。 | Laurel E Murphy James L Mills Anne M Molloy Cong Qian Tonia C Carter Helena Strevens Dag Wide-Swensson Aleksander Giwercman Richard J Levine | 2011 | Asian Journal of Andrology2011，13，6： | 2 |
| 3 | Skin fold thickness at abdomen:a simple anthropometric measurement may compliment metabolic syndrome definition in patients with normal waist circumference显示文摘Backgroud and Objectives Previous studies have reported that skin fold thickness (SF) strongly correlated with insulin resistance in the metabolic syndrome (MetS). In this study, we developed a MetS definition by SF at A8 point (SFA8) on Erdheim diagram(MetSSFA8) in essential hypertensive patients. Subjects and Methods Medical records of 268 essential hypertensive patients (126males and 122 females) were analyzed, including 210 non-diabetic patients (NDM group) and 58 patients with diabetes (DM group).The mean age was 61.4 ± 9.9 and 59.0 ± 11.0 years, respectively. The control group consisted of 90 non-diabetic, non-hypertensive patients with a mean age of 58.0 ± 11.3 years. The proposed MetSSFA8 definition included SFA8 specific values ( ≥30 mm in female and ≥27 mm in male) and at least two of the following: raised triglyceride levels ( ≥1.7 mmol/L), or specific treatment for this lipid abnormality; raised blood pressure (SBP≥130 mmHg and/or DBP≥85 mmHg), or treatment of previously diagnosed hypertension;reduced HDL-cholesterol (< 1.03 mmol/L in men, <1.29 mmol/L in women), or specific treatment for this lipid abnormality; raised fasting plasma glucose (≥5.6 mmol/l), or previously diagnosed DM. Metabolic Syndrome by the National Cholesterol Education Program and International Diabetes Federation definitions were determined with abdominal obesity defined by Asia-Pacific criteria for waist circumference (NCEPA and IDFA). Results The percentage of MetS as defined by NCEPA, IDFA and MetSSFA8 in NDM group was lower than that of NCEPA, IDFA and MetSSFA8 in DM group [OR=7.7 (95%CI, 2.9-20.2) and 2.5 (95%CI, 1.4-4.8) and 2.7(95%CI, 1.3-5.6), respectively] and higher than that of the control group [OR=53.3 (95%CI, 16.7-170.6), 5.8 (95%CI, 2.6-13.2) and18.8 (95%CI, 7.3-48.7), respectively]. The percentage of MetS by NCEPA, IDFA and MetSSFA8 in males in NDM group was lower than the percentage of MetS by NCEPA, IDFA and MetSSFA8 in females in NDM group (50.8% and 77.9%, P< 0.001; 15,9% and 67.2%, P< 0.001; 60.3% and 73.8%, P <0.05, respectively). In subjects with normal WC or both normal WC and BMI, the percentage of MetS by SFAS was higher than that the percentage of MetS by NCEPA (36.9% and 50.8%, P< 0.05 and 36.0% and 51.0%, P< 0.05).The sensitivity, specificity, false positive rate, positive predictive value, negative predictive value of MetSSFA8 assessed with NCEPA definitions were 0.87, 0.73, 0.27, 0.79 and 0.82, respectively. There was a close agreement between MetSSFA8 and NCEPA (The coefficient of Kapa was 0.60, P< 0.001). Conclusions The MetSSFA8 definition was developed which may be useful in order to define and manage MetS in patients with normal WC or normal weight. | Toan C Nguyen Thai Q Ngo Son V Nguyen Hieu T Luong Khoa TA Pham Cong D Nguyen | 2006 | Journal of Geriatric Cardiology2006，3，2： | 2 |
| 4 | Development of highly specific fluorescence immunoassay and enzyme - linked immunosorbent assay for detection of dimethyl phthalate in water samples显示文摘 | Zhang M C Liu B L Cong Y | 2011 | Food and Agricultural Immunology2011，22，： | 1 |
| 5 | Chiral analyses of peptides by ion/molecule reactions显示文摘 | GRIGOREAN G CONG X LEBRILLA C B | 2004 | Int J Mass Spectrom2004，234，123： | 1 |
| 6 | Acute inflammatory reaction following experimental intracerebral hemorrhage in rat显示文摘 | Cong C Hoff J T Keep R F | 2000 | Brain Res2000，871，1： | 1 |
| 7 | Synthesis,Structure and Ferromagnetic Properties of Ni-Doped ZnO Nanoparticles 显示文摘 | Cong C J Hong J H Liu Q Y | 2006 | Solid State Commun2006，138，： | 1 |
| 8 | Dag-map: graph-based FPGA technology mapping for delay optimization 显示文摘 | Chen K C Cong J Ding Y | 1992 | IEEE Design & Test of Computers1992，9，3： | 1 |
| 9 | Elemental composition of aerosol in the Nam Co region,Tibetan Plateau, during summer monsoon season 显示文摘 | CONG Z Y KANG S C LIU X D | 2007 | Atmospheric Environment2007，41，6： | 1 |
| 10 | Effects of Temperature on The Ferromagnetism of Mn-Doped ZnO Nanoparticles and Mn-Related Raman Vibration显示文摘 | Cong C J Liao L Liu Q Y | 2006 | Nanotechnology2006，17，： | 1 |
| 11 | Kinetics of thermal decomposition of nickel oxalate dehydrate in air 显示文摘 | Zhan D Cong C J Diakite K | 2005 | Thermochim Acta2005，430，112： | 1 |
| 12 | 显示文摘 | Hong J H Cong C J Zhang Z G | 2007 | J Phys Chem Solids2007，68，7： | 1 |
| 13 | Differential regulation of prostaglandin production mediated by corticotropimreleasing hormone receptor type 1 and type 2 in cultured human placental tropho blasts显示文摘 | Gao L Lu C Xu C Tao Y Cong B Ni X | 2008 | Endocrinology2008，149，： | 1 |
| 14 | Performance optimization of VLSI interconnect layout显示文摘 | J Cong L He C K Koh | 1996 | Integration:The VLSI J1996，21，： | 1 |
| 15 | Giant enhancement of top emission from ZnO thin film by nanopattemed Pt 显示文摘 | LIU K W TANG Y D CONG C X | 2009 | Appl Phys Lett2009，94，15： | 1 |
| 16 | Inhibition of Newcastle disease virus replication by lentivirus-mediated RNA interference显示文摘 | Wang Z Ding Z Ding C Yu S Dang Y Guo Y Yang J Meng Q Liu J Cong Y | 2013 | Avian Dis2013，57，2： | 1 |
| 17 | Multihydroxy polymer- functionalized carbon nanotubes:Synthesis derivatization and metal loading 显示文摘 | GAO C CONG D JING Y | 2005 | Macromolecules2005，38，21： | 1 |
| 18 | Electrocatalytic generation of radical intermediates over lead dioxide electrode doped with fluoride 显示文摘 | Cong Y Q Wu Z C | 2007 | Journal of Physical Chemistry C2007，111，8： | 1 |
| 19 | Inhibition of atrogin - 1/MAFbx ex- pression by adenovirus - delivered small hairpin RNAs attenuates muscle atrophy in fasting mice 显示文摘 | Cong H Sun L Liu C | 2011 | Hum Gene Ther2011，22，3： | 1 |
| 20 | Kinetics of thermal de-composition of nickel oxalate dihydrate in air显示文摘 | Zhan D Cong C J Diakite K | 2005 | Ther-mochimica Acta2005，430，： | 1 |
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