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| 1 | New Opportunities for Lanthanide Luminescence显示文摘三价的 lanthanide 离子显示迷人的光性质。相应元素和他们的第一工业使用的发现亲密地被连接到他们的光性质。这种关系被使活着直到什么时候的今天象节省精力的灯光的设备,显示,光纤维和放大器,激光,为生物医学的分析并且在察觉到的 celluio 的应答的光污点和成像那样的包含 lanthanide 材料的许多高科技应用,重重地依靠 lanthanide 离子的灿烂、纯颜色的排放。在这评论,我们首先在 f-f 转变,促进感受性机制,和对包含 lanthanide 的光效率的评价上与强调构画出 lanthanide 光的基础放射性的分子的大厦。强调然后被放在 lanthanide 光的二个快发展中方面上:为电信和轻射出二极管的材料,和生物医学的成像并且察觉到。在为塑料放大器和波导的射出 NIR 材料的最近的进展被描述,和最小化激动的状态的非放射的释放的研究人员带的主要答案。在 1999 那耳 tris (8-hydroxyquinolinate ) 的示范显示了合适的明亮绿的排出物因为射出二极管(OLED ) 的器官的光被认识到在 OLED, 25% 刺激精力导致汗衫状态, 75% 说到三位字节跟随。因为 lanthanide 离子是好三位字节,熄灭 ers,他们现在也在这些灯光的设备的发展起一个关键作用。生物分子的光分析在知道的最敏感的分析技术之中。lanthanide 的长一生使状态激动允许解决时间的光谱学被过去常,压制样品汽车荧光并且到达很低的察觉限制。可见 lanthanide 传感器现在无所不在地不仅在医药诊断并且在房间成像被规定,而且使用象 Yb (III ) 那样的离子的 NIR 排放的可行性现在是因为更深的穿入,在生物纸巾被测试。 | Jean-Claude G. Bünzli Steve Comby Anne-Sophie Chauvin Caroline D. B. Vandevyver | 2007 | Journal of Rare Earths2007，25，3： | 31 |
| 2 | Newopportu-nitiesforlanthanideluminescence 显示文摘 | BünzliJC- CombyS ChauvinAS etal | 2007 | J Rare Earth2007，25，3： | 1 |
| 3 | The highest back-ground radiation school in the world and the health status of itsstudents and their offspring显示文摘 | Borzoueisileh S Monfared AS Comby B | 2014 | Isotopes Environ Health Stud2014，50，1： | 1 |
| 4 | Maize HapMap2 identifies extant variation from a genome in flux 显示文摘 | Jer-Ming Chia Chi Song Peter J Bradbury Denise Cos- tich Natalia de Leon John Doebley Robert J Elshire Brandon Gaut Laura Geller Jeffrey C Glaubitz Michael Gore Kate E Guill Jim Holland Matthew B Hufford Jinsheng Lai Meng Li Xin Liu Yanli Lu Richard Mc- Combie Rebecca Nelson Jesse Poland Boddupalli M Prasanna Tanja Pyhajarvi Tingzhao Rong Rajandeep S Sekhon Qi Sun Maud I Tenaillon Feng Tian Jun Wang Xun Xu Zhiwu Zhang Shawn M Kaeppler Jef- frey Ross-lbarra Michael D McMullen Edward S Buck- ler Gengyun Zhang Yunbi Xu Doreen Ware | 2012 | Nat Genet2012，，44： | 1 |
| 5 | Telaprevir- and boceprevir-based tritherapies in real practice for F3-F4 pretreated hepatitis C virus patients显示文摘AIM:To assess,in a routine practice setting,the sus-tained virologic response(SVR) to telaprevir(TPV) or boceprevir(BOC) in hepatitis C virus(HCV) nullresponders or relapsers with severe liver fibrosis.METHODS:One hundred twenty-five patients were treated prospectively for 48 wk with TPV or BOC + pegylated-interferon(peg-INF) α2a + ribavirin(PR) according to standard treatment schedules without randomization.These patients were treated in routine practice settings in 10 public or private health care centers,and the data were prospectively collected.Only patients with severe liver fibrosis(Metavir scores of F3 or F4 upon liver biopsy or liver stiffness assessed by elastography),genotype 1 HCV and who were null-responders or relapsers to prior PR combination therapy were included in this study.RESULTS:The Metavir fibrosis scores were F3 in 35(28%) and F4 in 90(72%) of the patients.In total,62.9% of the patients were null-responders and 37.1% relapsers to the previous PR therapy.The overall SVR rate at 24 wk post-treatment withdrawal was 59.8%.The SVR was 65.9% in the TPV group and 44.1% in the BOC group.Independent predictive factors of an SVR included a response to previous treatment,relapsers vs null-responders [OR = 3.9;(1.4,10.6),P = 0.0084],a rapid virological response(RVR) [OR 6.9(2.6,18.2),P = 0.001] and liver stiffness lower than 21.3 kPa [OR = 8.2(2.3,29.5),P = 0.001].During treatment,63 patients(50.8%) had at least one severe adverse event(SAE) of grade 3 or 4.A multivariate analysis identified two factors associated with SAEs:female gender [OR = 2.4(1.1,5.6),P = 0.037] and a platelet count below 150 × 103/ mm3 [OR = 5.3(2.3,12.4),P ≤ 0.001].CONCLUSION:More than half of these difficult-to-treat patients achieved an SVR and had SAEs in an actual practice setting.The SVR rate was influenced by the response to previous PR treatment,the RVR and liver stiffness. | Delphine Bonnet Matthieu Guivarch Anais Palacin Laurent Alric Emilie Bérard Jean-Marc Combis Andre Jean Remy Andre Glibert Jean-Louis Payen Sophie Metivier Karl Barange Herve Desmorat Florence Nicot Florence Abravanel | 2014 | World Journal of Hepatology2014，6，9： | 1 |
| 6 | A versatile ditopic ligand system for sensitizing the luminescence of bimetallic lanthanide bin-imaging probes显示文摘 | Chauvin A S Comby S C Song B | 2008 | Chem Eur J2008，14，6： | 1 |
| 7 | A new method for the measurement of tremor at rest显示文摘 | COMBY B CHEVALIER G BOUCHOUCHA M | 1992 | Archives Internationales de Physiologie de Biochimie et de Biophysique1992，100，1： | 1 |
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