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| 1 | In vivo evaluation of riboflavin receptor targeted fluorescent USPIO in mice with prostate cancer xenografts显示文摘核黄素(Rf ) 受体绑并且 translocate Rf 和它的 phosphorylated 形式(例如黄素 mononucleotide,黄素单核甘酸) 进他们调停的房间各种各样的细胞的新陈代谢的小径。以前,我们证明黄素单核甘酸涂的 ultrasmall superparamagnetic 氧化铁(FLUSPIO ) nanoparticles 对在 vitro 把新陈代谢地活跃的癌症和 endothelial 房间标记合适。在这研究,我们集中了于在里面用前列腺癌症异种皮移植的 FLUSPIO 的 vivo 申请。FLUSPIO 的尺寸,充电,和化学作文被评估。我们探索了在里面为它用磁性的回声成像(MRI ) 和染色的普鲁士的蓝色的细胞的受体的 FLUSPIO 的 vitro 特性。竞争有约束力的实验被在过量注射免费黄素单核甘酸在 vivo 执行。FLUSPIO 的简历分发被用比色的试金在机关和肿瘤估计铁内容决定。AFM 分析和希腊语的第六个字母潜力大小揭示了微粒形态学在尺寸和一个否定希腊语的第六个字母潜力的近似 20-40 nm (-24.23 ??????????? | Jabadurai Jayapaul Susanne Ares Matt Bunker Marek Weiler Sandra Rutherford Peter Comba Fabian Kiessling | 2016 | Nano Research2016，9，5： | 3 |
| 2 | Direct anterior approach hip arthroplasty:How to reduce complications-A 10-years single center experience and literature review显示文摘BACKGROUND The direct anterior approach for total hip arthroplasty(DAA-THA)is increasing in popularity due to some advantages such as less surgical trauma,minimal dissection of soft tissues,shorter rehabilitation times,faster return to daily activities,lower incidence of dislocation.On the other hand,the literature reports a high rate of intraoperative complications,with many different rates and complication types in the published papers.AIM To analyze our complications comparing results with the literature;to report measures that we have taken to reduce complications rate.METHODS All DAA-THA patients with one year minimum follow up who were operated at a single high-volume centre,between January 2010 and December 2019 were included in this retrospective study.All surgeries were performed using cementless short anatomical or straight stems and press fit cups.Patients’followup was performed,at 6 wk,3 mo,then annually post-surgery with clinical and radiological evaluation.Primary outcomes were stem revision for aseptic loosening and all-cause stem revision.Second outcome was intra-operative and post-operative complications identification.RESULTS A total of 394 patients underwent DDA-THA from January 2010 and December 2019,for a total of 412 hips;twelve patients lost to follow-up and one patient who died from causes not related to surgery were excluded from the study.The average age at the time of surgery was 61 years(range from 28 to 78 years).Mean follow-up time was 64.8 mo(range 12-120 mo).Seven stems were revised.One cortical perforation,one trochanteric and lateral cortical wall intraoperative fracture,one diaphyseal fracture,three clinically symptomatic early subsidence and one late aseptic loosening.We also observed 3 periprosthetic fractures B1 according to the Vancouver Classification.Other minor complications not requiring stem revision were 5 un-displaced fractures of the calcar region treated with preventive cerclage,one early infection,one case of late posterior dislocation,18 case of asymptomatic stem subsidence,6 cases of lateral cutaneous femoral nerve dysesthesia.CONCLUSION DAA is associated to good outcomes and lower incidence of dislocation.Complication rate can be reduced by mindful patient selection,thorough preoperative planning,sufficient learning curve and use of intraoperative imaging. | Fabrizio Rivera Luca C Comba Alessandro Bardelli | 2022 | World Journal of Orthopedics2022，13，4： | 2 |
| 3 | A randomised phase II study of oxaliplatin alone versus oxaliplatin combined with 5-fluorouracil and folinic acid (Mayo Clinic regimen) in previously untreated metastatic colorectal cancer patients显示文摘 | Zori Comba A Blajman C Richardet E | 2001 | Eur J Cancer2001，37，： | 1 |
| 4 | Structural and mechanistic studies of the copper (II)-assisted orthohydroxylation of benzoates by trimethylamine N-oxide 显示文摘 | BULLS W COMBA P CORNELI D | 2002 | J Organometal Chem2002，641，12： | 1 |
| 5 | Comparison of immu- noassay with a conventional method for the determination of diazion in surface waters 显示文摘 | Zaruk D Comba M Struger J | 2001 | Anal Chim Acta2001，444，1： | 1 |
| 6 | Combining C - reactive protein and interleukin -6 may be useful to detect periprosthetic hip infection 显示文摘 | Buttaro MA Tanoira I Comba F | 2010 | Clinical Orthopaedics and Related Research2010，468，12： | 1 |
| 7 | Relationship between plasma glucose,bram lactate and intracellular PH during cerebral inchemia in gerbila显示文摘 | Comba DJ Demprey RJ Maley M | 1990 | Stroke1990，21，6： | 1 |
| 8 | An adaptive framework for visualization unstructured grids with time-varying scalar fields 显示文摘 | Bemardon F F Callahan S P Comba J L D | 2007 | Parallel Computing2007，，33： | 1 |
| 9 | A randomised phase Ⅱ study of oxaliplatin alone versus oxaliplatin combined with 5-fluorouracil and folinic acid (Mayo Clinic regimen) in previously untreated metastatic colorectal cancer patients显示文摘 | Zori Comba A Blajman C Richardet E | 2001 | Eur J Cancer2001，37，8： | 1 |
| 10 | Iron coor- dination chemistry with tetra-, penta- and hexadentate bispi- dine-type ligands显示文摘 | Heidi Barzel Peter Comba Karl S Hagen | 2002 | Inorganica Chimica Acta2002，337，： | 1 |
| 11 | The use of femoral struts and impacted cancellous bone allograft in patients with severe femoral bone loss who undergo revision total hip replacement: a three - to nine - year follow - up显示文摘 | Buttaro MA CostantiniJ Comba F | 2012 | J BoneJoint Surg Br2012，94，2： | 1 |
| 12 | A randomised phase Ⅱ study of oxaliplatin alone versus oxaliplatin combined with 5-fluorouracil and folinic acid (Mayo Clinic regimen) in previously untreated metastatic colorectal cancer patients显示文摘 | Zori Comba A Blajman C Richardet E | 2001 | Eur J Cancer2001，37，8： | 1 |
| 13 | A randomized phase Ⅱstudy of oxaliplatin alone versus oxaliplatin combined with 5-fluorouracil and folinic acid(Mayo clinic regimen)in previously untreated meta2 static colorectal cancer patients显示文摘 | Zori Comba A Blaiman C Riehardet E | 2001 | Eur J Cancer2001，37，8： | 1 |
| 14 | The use of femoral struts and impacted cancellous bone allograft in pa- tients显示文摘 | Buttaro MA1 Costantini J Comba F | 2012 | J Bone Joint Surg Br2012，94，2： | 1 |
| 15 | A randomised phase II study of oxaliplatin alone versus oxaliplatin combined with 5 - fluorouracil and folinic acid (Mayo clinic regimen) in previously untreated meta2 static colorectal cancer patients 显示文摘 | Zori Comba A Blajiman C Richardet E | 2001 | Eur J Cancer2001，37，8： | 1 |
| 16 | The use of femoral struts and impacted cancel ous bone al ograft in patients with severe femoral bone loss who undergo revision total hip replacement:a three-to nine-year fol ow-up显示文摘 | Buttaro MA Costantini J Comba F | | 0，，02： | 1 |
| 17 | A randomised phase Ⅱ study of oxaliplatin alone versus oxaliplatin combined with 5-fluorouracil and folinic acid (mayo clinic regimen) in previously untreated metastatic colorectal cancer patients显示文摘 | Zori Comba AB Blajiman C Richardet E | 2001 | Eur J Cancer2001，37，： | 1 |
| 18 | The utility and precision of analogue and digital preoperative planning for total hip arthroplasty显示文摘 | Gonzolez Della Valle A Comba F Taveras N | 2008 | Int Orthop2008，32，3： | 1 |
| 19 | The utility and precision of analogue and digital preoperative planning for total hip arthroplasty显示文摘 | Gonzalez Della Valle A Comba F Taveras N | | 0，，03： | 1 |
| 20 | Combinatorial chemoprevention reveals a novel smoothened-independent role of GLI1 in esophageal carcinogenesis显示文摘 | Rizvi S Demars C J Comba A | 2010 | Cancer Res2010，70，17： | 1 |
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