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| 1 | Single-lung transplantation in emphysema:Retrospective study analyzing survival and waiting list mortality显示文摘AIM: To performed remains a subject of debate and is the principal aim of the study. METHODS: This retrospective analysis included 73 patients with emphysema(2000-2012). The outcomes of patients undergoing single-lung transplantation(SL)(n = 40) or double-lung transplant(DL)(n = 33) were compared in a Cox multivariate analysis to study the impact of the technique, postoperative complications and acute and chronic rejection on survival rates. Patients were selected for inclusion in the waiting list according to the International Society of Heart Lung Transplantation criteria. Pre and postoperative rehabilitation and prophylaxis, surgical technique and immunosuppressive treatment were similar in every patients. Lung transplantation waiting list information on a national level and retrospective data on emphysema patient survival transplanted in Spain during the study period, was obtained from the lung transplantation registry managed by the National Transplant Organization(ONT). RESULTS: Both groups were comparable in terms of gender and clinical characteristics. We found significant differences in the mean age between the groups, the DL patients being younger as expected from the inclusion criteria. Perioperative complications occurred in 27.6% SL vs 54% DL(P = 0.032). Excluding perioperative mortality, median survival was 65.3 mo for SL and 59.4 mo for DL(P = 0.96). Bronchiolitis obliterans and overall 5-year survival were similar in both groups. Bacterialrespiratory infection, cytomegalovirus and fungal infection rates were higher but not significant in SL. No differences were found between type of transplant and survival(P = 0.48). To support our results, national data on all patients with emphysema in waiting list were obtained(n = 1001). Mortality on the waiting list was 2.4% for SL vs 6.2% for DL. There was no difference in 5 year survival between 235 SL and 430 DL patients transplanted(P = 0.875).CONCLUSION: Our results suggest that SL transplantation in emphysema produce similar survival than DL with less postoperative complication and significant lower mortality in waiting list. | José M Borro María Delgado Elisabeth Coll Salvador Pita | 2016 | World Journal of Transplantation2016，6，2： | 6 |
| 2 | Modulation of inflammatory response by hippocampus of rats exposed to cerebral ischemia/reperfusion显示文摘 | Coll the PPAR ino M Aragno M Ma oxidative stress -gamma agonists in stro and the cola R et a7 | 2006 | Eur J Pharmacol2006，530，： | 1 |
| 3 | A review of image denoising algorithms with a new one显示文摘 | Buades A Coll B Morel J M | 2005 | Multiscale Modeling and Simulation:A SIAM Interdisciplinary Journal2005，4，2： | 1 |
| 4 | A review of image denoising algorithms, with a new one 显示文摘 | BUADES A COLL B MOREL J M | 2005 | Multiscale Modeling and Simulation2005，4，2： | 1 |
| 5 | A review of image denoising algorithms,with a new one显示文摘 | Buades A Coll B Morel J M | 2005 | Multiscale Model Simul2005，4，2： | 1 |
| 6 | The organic compounds of gold: Part II : Co - ordination compounds 显示文摘 | GIBSON C S COLLES W M | 1931 | J Chem Soc1931，，： | 1 |
| 7 | Finite element analysis of drawing of multifilamentary wires显示文摘 | Peng X Sumption M D Collings E W | 2005 | IEEE Transact Appl Supercond2005，15，2： | 1 |
| 8 | Selenium in human health and disease 显示文摘 | BAO Y BROADLEY M R COLLINGS R | 2011 | Antioxid Redox Signal2011，14，7： | 1 |
| 9 | Neighborhood Filters and PDE's显示文摘 | Buades A Coll B Morel J M | 2006 | Numerische Mathematik2006，105，1： | 1 |
| 10 | Nonlocal image and movie denoising 显示文摘 | BUADES A COLL B MOREL J M | 2007 | International Journal of Computer Vision2007，76，2： | 1 |
| 11 | Circadian pharmacokinetics of methotrexate显示文摘 | ROBINSON B A BEGG E J COLLS B M | 1989 | Cancer Chemother Pharmacol1989，24，6： | 1 |
| 12 | On image denoising methods显示文摘 | BUADES A COLL B MOREL J M | | 0，，： | 1 |
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| 14 | On image denoising methods 显示文摘 | BUADES A COLL B MOREL J M | 2005 | SIAM Multiscale Modeling and Simulation2005，4，2： | 1 |
| 15 | On Image Denoising Method显示文摘 | Baudes A Coll B Morel J M | 2005 | SIAM Multiscale Modeling and Simulation2005，4，2： | 1 |
| 16 | A review of image de-noising algorithms, with a new one 显示文摘 | BUADES A COLL B MOREL J M | 2005 | Multi-scale Modeling and Simulation2005，4，： | 1 |
| 17 | Trophic flows,e-cosystem structure and fishing impacts in the South CatalanSea,Northwestern Mediterranean显示文摘 | Coll M Palomera I Tudela S | 2006 | Journal of Marine Sys-tems2006，59，： | 1 |
| 18 | Flow patterns in an ul- trasonic liquid flow meter显示文摘 | Emperley N C Behnia T M Collings A F | 2000 | Flow Measurement and Instrumen- tation2000，11，： | 1 |
| 19 | Neighborhood filters and PDE′s显示文摘 | BUADES A COLL B MOREL J M | | 0，，10： | 1 |
| 20 | Elicitor stimula- ted ion fluxes and O2 from the oxidative burst are essential components in triggering defense gene activation and phytoa- lexin synthesis in parsley显示文摘 | JABS T TSCHOPE M COLLING C | 1997 | Proc Natl Acad Sci1997，94，： | 1 |
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