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1076篇 您的检索式:作者名="Cole P"
    题名 作者 年代 出处 被引量
1干扰素调节因子5通过损伤胞葬作用控制动脉粥样硬化病变中的坏死核心形成显示文摘髓系细胞是动脉粥样硬化病变发展和易损斑块形成的核心。动脉吞噬细胞吸收凋亡细胞(胞葬作用)的能力受损,可促进病变生长并建立坏死核心。干扰素调节因子(interferon regulatory factor,IRF)5是髓系细胞功能的重要调节因子。该研究试图确定IRF5是否影响动脉粥样硬化病变的形成和表型。方法:通过两种互补模型,研究IRF5在动脉粥样硬化中的作用:Seneviratne AN Edsfeldt AO Cole JE Kassiteridi C Swart M Park I Green P Khoyratty TE Saliba DG Goddard ME Sansom SN Goncalves I Krams R Udalova IA Monaco C 刘莉 叶鹏 2017中华高血压杂志2017,25,8:9
2Platelet-rich plasma for muscle injuries: A systematic review of the basic science literature显示文摘BACKGROUND Platelet-rich plasma(PRP) is an increasingly used biologic adjunct for muscle injuries, as it is thought to expedite healing. Despite its widespread use, little is known regarding the mechanisms by which PRP produces its efficacious effects in some patients.AIM To clarify the effects of PRP on muscular pathologies at the cellular and tissue levels by evaluating the basic science literature.METHODS A systematic review of PubMed/MEDLINE and EMBASE databases was performed using the Preferred Reporting Items for Systematic Reviews and MetaAnalyses(PRISMA) guidelines and checklist. Level III in vivo and in vitro studies examining PRP effects on muscles, myocytes and/or myoblasts were eligible for inclusion. Extracted data included PRP preparation methods and study results.RESULTS Twenty-three studies were included(15 in vivo, 6 in vitro, 2 in vitro/in vivo). Only one reported a complete PRP cytology(platelets, and red and white blood cell counts). Five in vitro studies reported increased cellular proliferation, four reported increased gene expression, and three reported increased cellular differentiation. Five in vivo studies reported increased gene expression, three reported superior muscle regeneration, and seven reported improved histological quality of muscular tissue.CONCLUSION The basic science literature on the use of PRP in muscle pathology demonstrates that PRP treatment confers several potentially beneficial effects on healing in comparison to controls. Future research is needed to determine optimal cytology,dosing, timing, and delivery methods of PRP for muscle pathologies.Kyle N Kunze Charles P Hannon Jared D Fialkoff Rachel M Frank Brian J Cole 2019World Journal of Orthopedics2019,10,7:6
3Response of dairy cows to high doses of a sustained- release bovine somatotropin administered during two lactations显示文摘EPARD P J HUDSON S COLE W J 1991J Dairy Sci1991,74,:2
4Terminal restriction fragment length polymorphism an analysis program,a web-based research tool for microbial community analysis显示文摘Marsh T L Saxman P Cole J 2000Appl Environ Microbiol2000,66,8:1
5Double intussusception fatally complicated by clostridial infection in a dog(a case report) 显示文摘Okewole P A Odeyemi P S Cole T 1989Br Vet J1989,145,3:1
6Intracellular P-gp contributes to functional drug efflux and resistance in acute myeloid leukaemia 显示文摘Ferrao P Sincock P Cole S 2001Leuk Res2001,25,5:1
7The soluble tumor necrosis factor receptor etanercept:a new strategy for the treatment of autoimmune rheumatic disease 显示文摘Cole P Rabasseda X 2004Drugs Today(Spain)2004,40,4:1
8Inflammation: a two-edged sword-the model of bronchiectasis 显示文摘Cole P J 1986Eur J Respir Dis Suppl1986,147,:1
9Terretonin,a toxic compound from Aspergillus terreus显示文摘Springer J P Dorner J W Cole R J 1979J OrgChem1979,44,26:1
10Radiographic follow-up of 84 operatively treated scapula neck and body fractures显示文摘Cole P A Gauger E M Herrera D A 0,,03:1
11A review of cognitive teaching models显示文摘Wilson B Cole P 0,,04:1
12Peroxi- some proliferator-activated receptor gamma (PPAR gam- ma) and its ligands: a review 显示文摘HOUSEKNECHT K L COLE B M STEELE P J 2002Domest Anim Endocri- nol2002,22,1:1
13Turn Customer Service intl Customer Profitability显示文摘 Cole P M 1994Management Review1994,83,7:1
14Characterization of neogenin-expressing neural progenitor populations and migrating neuroblasts in the embryonic mouse forebrain显示文摘Fitzgerald D P Cole S J Hammond A 2006Neuroscience2006,142,3:1
15The influence of Mg doping on the materials properties of Ba1-xSrxTiO3 thin films for tunable device applications 显示文摘Cole M W Joshi P C Ervin M H 2000Thin Solid Films2000,374,:1
16Buoyancy and drug release patterns of floating minitablets containing piretanide and atenolol as model drugs显示文摘Rouge N Cole ET Buri P 1998Pharm Dev echnol1998,3,1:1
17Plumbing the Global Carbon Cycle: integrating inland waters into the terrestrial carbon budget 显示文摘Cole JJ Prairie YT Caraco NF McDowell WH Tranvik LJ Striegl RG Duarte CM Kortelainen P Downing JA Middelburg JJ Melack J 2007Ecosystems2007,10,:1
18Carbon dioxide concentration and atmospheric flux in the Hudson River 显示文摘Raymond P A Caraco N F Cole J J 1997Estuaries1997,20,2:1
19Surgical technique:a minimally invasive approach to scapula neck and body fractures显示文摘Gauger E M Cole P A 0,,12:1
20Non-involuting congenital haemangioma associated with high-output cardiomyopathy 显示文摘COLE P KAUFMAN Y METRY D 2009J Plast Reconstr Aesthet Surg2009,62,10:1
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