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37篇 您的检索式:作者名="Cmelak"
    题名 作者 年代 出处 被引量
1Clinical and scientific impact of human papillomavirus on head and neck cancer显示文摘Head and neck cancer(HNC) arises from the skull base to the clavicles and is the fifth most common cancer in the world by incidence. Historically, in the developed world HNC was associated with tobacco use and alcohol consumption, and the combination of the two produced a synergistic increase in risk. However, beginning in 1983, investigators have found a significant and growing proportion of HNC patients with human papillomavirus-positive(HPV) tumors who neither drank nor used tobacco. Since that time, there has been increased interest in the molecular biology of HPV-positive HNC. Multiple studies now show that HPV has shifted the epidemiological landscape and prognosis of head and neck squamous cell carcinoma(HNSCC). These studies provide strong evidence for improved survival outcomes in patients with HPV-positive HNSCC compared to those with HPV-negative HNSCC. In many reports, HPV status is the strongest predictor of locoregional control, disease specific survival and overall survival. In response to these findings, there has been significant interest in the best management of HPV-positive disease. Discussions within major cooperative groups consider new trials designed to maintain the current strong survival outcomes while reducing the long-term treatment-re-lated toxicities. This review will highlight the epidemiological, clinical and molecular discoveries surrounding HPV-related HNSCC over the recent decades and we conclude by suggesting how these findings may guide future treatment approaches.Jeffrey M Friedman Mark J Stavas Anthony J Cmelak 2014World Journal of Clinical Oncology2014,5,4:3
2Low-dose stereotactic radiosurgery is inadequate for medically intractable mesial temporal lobe epilepsy:a case report 显示文摘Cmelak AJ Abou-Khalil B Konrad PE 2001Seizure2001,10,6:1
3Prospective feasibility trial of radiotherapy target definition for head and neck cancer using 3-dimensional PET and CT imaging显示文摘Searfone C Lavely WC Cmelak A J 2004J Nucl Med2004,45,4:1
4Prospective feasibility trial of radiotherapy target definition for head and neck cancer using 3-dimensional PET and CT imaging 显示文摘Scarfone C Lavely WC Cmelak AJ 2004J Nucl Med2004,45,4:1
5Phase II trial of che- moradiation for organ preservation in reseetable stage Ⅲ-Ⅳ squamous cell carcinomous of the larynx or oropharynx : results of Eastern Cooperative Ontology Group Study E2399 显示文摘Cmelak AJ Li S Goldwasser MA 2007J Clin Oncol2007,25,:1
6Prospective feasibility rial of radiotherapy target definition for head and neck cancer using 3-dimensional PET and CT imaging显示文摘Scarfone C Lavely WC Cmelak AJ 2004Journal of Nuclear Medicine2004,45,4:1
7Taxane-based chemoirradiation for organ preservation with locally advanced head and neckcancer: results of a phase Ⅱ multi-institutional trial 显示文摘Cmelak A J Murphy BA Burkey B 2007Head Neck2007,29,4:1
8Evolution of clinical trials in head and neck cancer显示文摘Eddy S. Yang Barbara M. Murphy Christine H. Chung James L. Netterville Brian B. Burkey Jill Gilbert Wendell G. Yarbrough Robert Sinard Anthony J. Cmelak 2008Critical Reviews in Oncology and Hematology2008,,1:1
9Prospective feasibility trial of radiotherapy target definition for head and neck cancer using 3-dimensional PET and CT imaging 显示文摘Scarfone C Lavely WC Cmelak A J 2004J Nucl Med2004,45,4:1
10Radiosurgery for skull base malignancies and nasopharyngeal caxcinoma显示文摘Cmelak AJ Cox RS Adler JR 1997Int J Radiat Oncol Biol Phys1997,37,5:1
11Low-dose stereotactic radiosurgery is inadequate for medicallyintractable mesial temporal lobe epilepsy:a case report显示文摘Cmelak AJ Abou Khalil B Konrad PE et a1 2001Seizure2001,10,6:1
12Prospective feasibility trial of radiotherapy target definition for head and neck cancer using 3-dimensional PET and CT imaging 显示文摘Scarfone C Lavely WC Cmelak AJ 2004J Nucl Med2004,45,4:1
13Radiosurgery for skull base malignancies and nasopharyngeal carcinoma显示文摘Cmelak AJ Cox RS Adler JR 1997Int J Radiat Oncol Biol Phys1997,37,5:1
14Induction chemotherapy (IC) followed by concurrent chemoradiation (CCR) for organ preservation (OP) in locally advanced squamous head and neck cancer (SHNC):results of a phase Ⅱ trial显示文摘 Murphy BA Burkey B 2003Proc Am Soc Clin Oncol2003,22,:1
15Pattern of practice survey:non-small cell lung cancer in the US显示文摘Shyr Y Choy H Cmelak A 1998Proc Am Soc Clin Oncol1998,17,46:1
16National survey on prophy-lactic cranial irradiation: differences in practice patterns between medical and radiation oncologists 显示文摘Cmelak A J Choi H Shyr Y 1999Int J Radio Oncol Biol Phys1999,44,1:1
17National survey on prophylactic cranial irradiation: difference in practice patterns between medical and radiation oncologists显示文摘 Choy H Shyr Y 1999Int J Radiat Oncol Biol Phys1999,44,1:1
18Prospective feasibility trial of radiotherapy target definition for head and neck cancer using 3-dimensional PET and CT imaing显示文摘Scarfone C Lavely WC Cmelak A J 2004J Nucl Med2004,45,4:1
19Prospective feasibility trial of radiotherapy target definition for head and neck cancer using 3-dimensional PET and CT imaging显示文摘Scarfone C Lavely WC Cmelak AJ 2004Journal of Nuclear Medicine2004,45,4:1
20Long-term survival with whole abdominopelvic irradiation in platinum-refractory persistent or recurrent ovarian cancer显示文摘CMELAK A J KAPP D S 1997Gynecol Oncol1997,65,3:1
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