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3篇 您的检索式:作者名="Claudia Colombo"
    题名 作者 年代 出处 被引量
1Interaction of ionizing radiation with topotecan in two human tumor cell Lines 显示文摘Marchesini R Colombo A Claudia C 1996Int J Cancer1996,66,:1
2Orthotopic induction of CH157MN convexity and skull base meningiomas into nude mice using stereotactic surgery and MRI characterization显示文摘Meningioma in vivo research is hampered by the difficulty of establishing an easy and reproducible orthotopic model able to mimic the characteristics of a human meningioma. Moreover, leptomeningeal dissemination and high mortality are often associated with such orthotopical models, making them useless for clinical translation studies. An optimized method for inducing meningiomas in nude mice at two different sites is described in this paper and the high reproducibility and low mortality of the models are demonstrated. Skull base meningiomas were induced in the auditory meatus and convexity meningiomas were induced on the brain surface of 23 and 24 nude mice, respectively. Both models led to the development of a mass easily observable by imaging methods. Dynamic contrast enhanced MRI was used as a tool to monitor and characterize the pathology onset and progression. At the end of the study, histology was performed to confirm the neoplastic origin of the diseased mass.Francesca La Cava Alberto Fringuello Mingo Pietro Irrera Aldo Di Vito Alessia Cordaro Chiara Brioschi Sonia Colombo Serra Claudia Cabella Enzo Terreno Luigi Miragoli 2019Animal Models and Experimental Medicine2019,2,1:0
3Cardiovascular injuries and SARS-COV-2 infection:focus on elderly people显示文摘The novel coronavirus disease(COVID-19)has hit the healthcare system worldwide.The risk of severe infection and mortality increases with advancing age,especially in subjects with comorbidities such as cardiovascular disease,hypertension,diabetes,obesity and cancer.Moreover,cardiovascular complications such as myocardial injury,heart failure and thromboembolism are frequently observed in COVID-19 cases,and several biomarkers(troponin,NTpro BNP and D-Dimer)have been identified as prognostic indicators of disease severity and worst outcome.Currently,there is no specific therapy against SARS-Co V-2,although many medications are under investigation.The aim of this review will be to explore the intertwined relationship between COVID-19 disease and the cardiovascular system,focusing on elderly population.The available supportive treatments along with the related concerns in elderly patients,due to their comorbidities and polypharmacotherapy,will be explored.Claudia Colombo Laura Garatti Giulia Ferrante Francesca Casadei Claudio Montalto Gabriele Crimi Chiara Cogliati Enrico Ammirati Stefano Savonitto Nuccia Morici 2021Journal of Geriatric Cardiology2021,18,7:0
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