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253篇 您的检索式:作者名="Clark P F"
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1National trends in resection of the distal pancreas显示文摘AIM:To investigate national trends in distal pancreatectomy(DP) through query of three national patient care databases.METHODS:From the Nationwide Inpatient Sample(NIS,2003-2009),the National Surgical Quality Improvement Project(NSQIP,2005-2010),and the Surveillance Epidemiology and End Results(SEER,2003-2009) databases using appropriate diagnostic and procedural codes we identified all patients with a diagnosis of a benign or malignant lesion of the body and/or tail of the pancreas that had undergone a partial or distal pancreatectomy.Utilization of laparoscopy was defined in NIS by the International Classification of Diseases,Ninth Revision correspondent procedure code;and in NSQIP by the exploratory laparoscopy or unlisted procedure current procedural terminology codes.In SEER,patients were identified by the International Classification of Diseases for Oncology,Third Edition diagnosis codes and the SEER Program Code Manual,third edition procedure codes.We analyzed the databases with respect to trends of inpatient outcome metrics,oncologic outcomes,and hospital volumes in patients with lesions of the neck and body of the pancreas that underwent operative resection.RESULTS:NIS,NSQIP and SEER identified 4242,2681 and 11 082 DP resections,respectively.Overall,laparoscopy was utilized in 15%(NIS) and 27%(NSQIP).No significant increase was seen over the course of the study.Resection was performed for malignancy in 59%(NIS) and 66%(NSQIP).Neither patient Body mass index nor comorbidities were associated with operative approach(P = 0.95 and P = 0.96,respectively).Mortality(3% vs 2%,P = 0.05) and reoperation(4% vs 4%,P = 1.0) was not different between laparoscopy and open groups.Overall complications(10% vs 15%,P < 0.001),hospital costs [44 741 dollars,interquartile range(IQR) 28 347-74 114 dollars vs 49 792 dollars,IQR 13 299-73 463,P = 0.02] and hospital length of stay(7 d,IQR 4-11 d vs 7 d,IQR 6-10,P < 0.001) were less when laparoscopy was utilized.One and two year survival after resection for malignancy were unchanged over the course of the study(ductal adenocarinoma 1-year 63.6% and 2-year 35.1%,P = 0.53;intraductal papillary mucinous neoplasm and nueroendocrine 1-year 90% and 2-year 84%,P = 0.25).The majority of resections were performed in teaching hospitals(77% NIS and 85% NSQIP),but minimally invasive surgery(MIS) was not more likely to be used in teaching hospitals(15% vs 14%,P = 0.26).Hospitals in the top decile for volume were more likely to be teaching hospitals than lower volume deciles(88% vs 43%,P < 0.001),but were no more likely to utilize MIS at resection.Complication rate in teaching and the top decile hospitals was not significantly decreased when compared to non-teaching(15% vs 14%,P = 0.72) and lower volume hospitals(14% vs 15%,P = 0.99).No difference was seen in the median number of lymph nodes and lymph node ratio in N1 disease when compared by year(P = 0.17 and P = 0.96,respectively).CONCLUSION:There appears to be an overall underutilization of laparoscopy for DP.Centralization does not appear to be occurring.Survival and lymph node harvest have not changed.Armando Rosales-Velderrain Steven P Bowers Ross F Goldberg Tatyan M Clarke Mauricia A Buchanan John A Stauffer Horacio J Asbun 2012World Journal of Gastroenterology2012,18,32:8
2Proteomic analysis of the Arabidopsis nucleolus suggests novel nucleolar functions显示文摘Pendle A F Clark G P Boon R 2005Mol Biol Cell2005,16,:1
3Distance to nearest neighbor as a measure of spatial relationships in populations显示文摘Clark P J Evans F C 1954Ecology1954,35,4:1
4Transient expression and insertional mutagenesis of Puccinia triticina using biolistics显示文摘CRAIG A W LES J S GUUS B CLARKE G RICHARD C S MERLE E JOHN P F 2005Functional & Integrative Genomics2005,12,:1
5Distance to nearest neighbor as measure of spatial relationships in populations 显示文摘Clark P J Evans F C 1954Ecology1954,35,:1
6Distance to nearest neighbor as a measure ofspatial relationships in populations显示文摘Clark P J Evans F C 1954Ecology1954,35,4:1
7Distance to nearest neighbor as a mea- sure of spatial relationships in populations显示文摘Clark P J Evans F C 1954Ecology1954,35,4:1
8Distance to nearest neighbour as a measure of spatial relationships in populations 显示文摘CLARK P J EVANS F C 1954Ecology1954,35,:1
9Solution to the Simultaneous Localization and Map Building (SLAM) Problem 显示文摘G Dissnaayake P Newman S Clark H F Durrant-Whyte 2001IEEE Transactions of Robotics and Automation (S0018-9286)2001,17,3:1
10Electrically conductive geosynthetics for consolidation and reinforced soil 显示文摘HAMIR R B JONES C J F P CLARKE B G 2001Geotextiles and Geomembranes2001,19,8:1
11Partial degrees of substitution in cellulose nitrates determined by means of C-13 magnetic-reso- nance studies 显示文摘Clark D Stephenson P Heatley F 1981Polymer1981,22,8:1
12Facts and recommendations about total homocysteine determinations:an expert opinion显示文摘Refsum H Smith A D Ueland P M Nexo E Clarke R McPartlinJ Johnston C Engbaek F SchneedeJ McPartlin C Scott J M 2004Clinical Chemistry2004,50,1:1
13Fer de Lance virus (FDLV) : a probable paramyxovirus isolated from a reptile 显示文摘CLARK H F LIEF F S LUNGER P D 1979J Gen Virol1979,44,2:1
14RECK--a newly discovered inhibitor of metastasis with prognostic significance in multiple forms of cancer显示文摘CLARK J C THOMAS D M CHOONG P F 2007Cancer Metastasis Rev2007,26,:1
15The role of the thermohaline circulation in abrupt climate change显示文摘Clark P U Pisias N G Stocker T F 2002Nature2002,415,6874:1
16Distance to nearest neighbor as a measure of spatial relationships in populations显示文摘Clark P J Evans F C 1954Ecology1954,35,4:1
17Distance to nearest neighbour as a measure of spatial Relationships in populations显示文摘Clark P J Evans F C 1954Ecology1954,35,4:1
18Electrically conductive gsosynthetics for consolidation and reinforced soil显示文摘Hamir R B Jones C J F P Clarke B G 2001Geotextiles and Geomembranes2001,,19:1
19Kinetin inhibits protein oxidation and glycoxidation in vitro显示文摘Verbeke P Siboska G E Clark B F 2000Biochemical and Biophysical Research Communications2000,276,3:1
20Identifieation of immune photochemical biomarkers for papillary thyroid earcinoma using gene expression profiling 显示文摘Murphy K M Chen F Clark D P 2008Hum Patho12008,39,3:1
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