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40篇 您的检索式：作者名="Claing A"

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	题名	作者	年代	出处	被引量
1	Relation of atrophic gastritis with Helicobacter pylori-CagA^+ and interleukin-1 gene polymorphisms显示文摘AIM: To determine the association of Helicobacter pylori (H pylori) CagA+ infection and pro-inflammatory poly-morphisms of the genes interleukin (IL)-1RN and IL-1B with the risk of gastric atrophy and peptic ulcers in a dyspeptic population in Costa Rica, a country with high incidence and mortality of gastric cancer. METHODS: Seven biopsy specimens, a fasting blood sample and a questionnaire concerning nutritional and sociodemographic factors were obtained from 501 con-secutive patients who had undergone endoscopy for dyspeptic symptoms. A histopathological diagnosis was made. Pepsinogen concentrations were analyzed by enzyme linked immunosorbent assay (ELISA). Infection with H pylori CagA+ was determined by serology and polymerase chain reaction (PCR). IL-1B and IL-1RN polymorphisms genotyping was performed by PCR-restriction fragment length polymorphism (PCR-RFLP)and PCR respectively. RESULTS: In this dyspeptic population, 86% were H pylori positive and of these, 67.8% were positive for CagA. Atrophic antral gastritis (AAG) was associated with CagA+ status [odd ratio (OR) = 4.1; P < 0.000] and fruit consumption (OR = 0.3; P < 0.00). Atrophic body gastritis (ABG) was associated with pepsinogen PGI/PGII < 3.4 (OR = 4.9; P < 0.04) and alcohol consumption (OR = 7.3; P < 0.02). Duodenal ulcer was associated with CagA+ (OR = 2.9; P < 0.04) and smoking (OR = 2.4; P < 0.04). PGI < 60 μg/L as well as PGI/PGII < 3.4 were associated with CagA+. CONCLUSION: In a dyspeptic population in Costa Rica, H pylori CagA+ is not associated with ABG, but it is a risk factor for AAG. The pro-inflammatory cytokine poly-morphisms IL-1B + 3945 and IL-1RN are not associated with the atrophic lesions of this dyspeptic population.	Rafaela Sierra Clas Une Vanessa Ramírez Warner Alpízar-Alpízar María I González José A Ramírez Antoine de Mascarel Patricia Cuenca Guillermo Pérez-Pérez Francis Mégraud	2008	World Journal of Gastroenterology2008，14，42：	2
2	An exact algorithm for bilevel 0-1 knapsack problems显示文摘	Raid M Cla′udio A Vale′rio D C	2012	Mathematical Problems in Engineering2012，10，：	1
3	G protein-coupled receptors stimulation and the control of cell migration显示文摘	Cotton M Claing A	2009	Cell Signal2009，21，7：	1
4	Elderly trauma patientswith rib fractures are at greater risk of death and pneumoni-a显示文摘	Bergeron E Lavoie A Clas D	2003	J Trauma2003，54，3：	1
5	Simulation of interaction between a train in general motion and a track 显示文摘	CLAS A THOMAS A	2002	Vehicle Sys Dynamics2002，38，6：	1
6	G protein-coupled receptors stimulation and the control of cell migration显示文摘	Cotton M Claing A	2009	Cell Signal2009，21，7：	1
7	Homeostasis and anergy of CD4+CD25+s uppressor Tceilsinvivo显示文摘	Gavin M A Cla rke SR Negrou E et a1	2002	NatImmuno12002，3，1：	1
8	G protein-coupled receptors stimulation and the control of cell migration显示文摘	Cotton M Claing A	2009	Cell Signal2009，21，7：	1
9	Comparison of the contractile and calcium - increasing properties of platelet - activating factor and endothelin - 1in rat mesenteric artery and vein显示文摘	Claing A Shbaklo H Plante M	2002	Br J Phamacol2002，135，2：	1
10	beta2-Adrenergic receptor reg- ulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein显示文摘	Premont RT Claing A Vitale N	1998	Proc Natl Acad Sci U S A1998，95，14：	1
11	Rhoalogical properties of tetra-n-butylphosphonium bromide hydrate slurry flow显示文摘	CLA/N P DELAHAYE A FOURNAISON L	2012	Chemical Engineering Journal2012，193，：	1
12	G protein-coupled receptors stimulation and the control of cell migration 显示文摘	COTTON M CLAING A	2009	Cell Signal2009，21，7：	1
13	Twenty - four hour intermittent perfusion storage of the isolated rat heart: the effect of perfusion intervals on functional preservation 显示文摘	ZHU Q YANG X CLA YDON M A	1994	J Heart Lung Transplant1994，13，5：	1
14	beta-Arrestin-mediated ADP-ribosytation factor 6 activation and beta2-adrenergic receptor endocytosis显示文摘	Claing A Chen W Miller WE	2001	J Biol Chem2001，276，42：	1
15	Requirement for KuS0 in growth and immunoglobuIin V(D)J recombination 显示文摘	Nussenzweig A Chen C cla Costa Soares V	1996	Nature1996，382，：	1
16	Elderly trauma patients with rib fractures are at greater risk of death and pneumonia 显示文摘	Bergeron E Lavoie A Clas D	2003	J Trauma2003，54，3：	1
17	Elderly trauma patients with rib fractures are at greater risk of death and pneumonia显示文摘	Bergeron E Lavoie A Clas D	2003	J Trauma2003，54，3：	1
18	Beta-arrestin-mediated ADP-ribosylation factor 6 activation and beta 2-adrenergic receptor endocytosis显示文摘	Claing A Chen W Miller WE		0，，：	1
19	Bela2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activat- ing protein显示文摘	Premont RT Claing A Vitale N	1998	PNAS1998，95，14：	1
20	Neurokinins produce selective venoconstriction via NK - 3 receptors in the rat mesenteric vascular bed显示文摘	D'Orleans- Juste P Claing A Telemaque S	1991	Eur J Pharmacol1991，204，3：	1

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