维普期刊资源整合服务平台（V6.5）

维普中文期刊产品整合服务

1篇 您的检索式：作者名="Christopher M.Baker"

选中清除导出查看参考文献查看引证文献引用追踪共1页首页上一页第1页下一页末页 /1 跳转

		题名	作者	年代	出处	被引量
	1	Understanding the impact of disease and vaccine mechanisms on the importance of optimal vaccine allocation显示文摘Vaccination is an important epidemic intervention strategy.However,it is generally unclear how the outcomes of different vaccine strategies change depending on population characteristics,vaccine mechanisms and allocation objective.In this paper we develop a conceptual mathematical model to simulate strategies for pre-epidemic vaccination.We extend the SEIR model to incorporate a range of vaccine mechanisms and disease characteristics.We then compare the outcomes of optimal and suboptimal vaccination strategies for three public health objectives(total infections,total symptomatic infections and total deaths)using numerical optimisation.Our comparison shows that the difference in outcomes between vaccinating optimally and suboptimally depends on vaccine mechanisms,disease characteristics,and objective considered.Our modelling finds vaccines that impact transmission produce better outcomes as transmission is reduced for all strategies.For vaccines that impact the likelihood of symptomatic disease or dying due to infection,the improvement in outcome as we decrease these variables is dependent on the strategy implemented.Through a principled model-based process,this work highlights the importance of designing effective vaccine allocation strategies.We conclude that efficient allocation of resources can be just as crucial to the success of a vaccination strategy as the vaccine effectiveness and/or amount of vaccines available.	Isobel R.Abell James M.McCaw Christopher M.Baker	2023	Infectious Disease Modelling2023，8，2：	0

返回顶部每页显示：

共1页首页上一页第1页下一页末页 /1 跳转

goolge学术搜索-维普

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1　渝公网安备 50019002500403号　违法和不良信息举报中心

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费