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| 1 | Eosinophilic gastroenteritis:An unusual type of gastroenteritis显示文摘Eosinophilic gastroenteritis(EGE) is a rare disorder characterized by eosinophilic infiltration of the bowel wall with various gastrointestinal manifestations.Till date only 280 cases have been described in the literature.A high index of suspicion,by excluding other causes of peripheral eosinophilia,is a pre requisite for accurate diagnosis.EGE is an uncommon gastrointestinal disease affecting both children and adults.It was first described by Kaijser in 1937.Presentation may vary depending on location as well as depth and extent of bowel wall involvement and usually runs a chronic relapsing course.This condition can respond to low dose steroid therapy,thereby preventing grave complications like ascites and intestinal obstruction that might need surgical intervention.The natural history of EGE has not been well documented.Eosinophilic gastroenteritis is a chronic,waxing and waning condition.Mild and sporadic symptoms can be managed with reassurance and observation,whereas disabling gastrointestinal(GI) symptom flare-ups can often be controlled with oral corticosteroids.When the disease manifests in infancy and specific food sensitization can be identified,the likelihood of disease remission by late childhood is high.GI obstruction is the most common complication.Fatal outcomes are rare. | Sachin B Ingle Chitra R Hinge(Ingle) | 2013 | World Journal of Gastroenterology2013，19，31： | 47 |
| 2 | Primary intestinal lymphangiectasia: Minireview显示文摘Primary idiopathic intestinal lymphangiectasia is an unusual disease featured by the presence of dilated lymphatic channels which are located in the mucosa, submucosa or subserosa leading to protein loosing enteropathy.Most often affected were children and generally diagnosed before third year of life but may be rarely seen in adults too. Bilateral pitting oedema of lower limb is the main clinical manifestation mimicking the systemic disease and posing a real diagnostic dilemma to the clinicians to differentiate it from other common systemic diseases like Congestive cardiac failure, Nephrotic Syndrome, Protein Energy Malnutrition, etc. Diagnosis can be made on capsule endoscopy which can localise the lesion but unable to take biopsy samples. Thus, recently double-balloon enteroscopy and biopsy in combination can be used as an effective diagnostic tool to hit the correct diagnosis. Patients respond dramatically to diet constituting low long chain triglycerides and high protein content with supplements of medium chain triglyceride. So early diagnosis is important to prevent untoward complications related to disease or treatment for the sake of accurate pathological diagnosis. | Sachin B Ingle Chitra R Hinge(Ingle) | 2014 | World Journal of Clinical Cases2014，2，10： | 8 |
| 3 | Epithelial cysts of the spleen:A minireview显示文摘Primary splenic epithelial cyst is an unusual event in everyday surgical practice with about 800 cases reported until date in the English literature. Splenic cysts may be parasitic or non-parasitic in origin. Nonparasitic cysts are either primary or secondary. Primary cysts are also called true,congenital,epidermoid or epithelial cysts. Primary splenic cysts account for 10% of all benign non-parasitic splenic cysts and are the most frequent type of splenic cysts in children. Usually,splenic cysts are asymptomatic and can be found incidentally during imaging techniques or on laprotomy. The symptoms are related to the size of cysts. When they assume large sizes,they may present with fullness in the left abdomen,local or referred pain,symptoms due to compression of adjacent structures(like nausea,vomiting,flatulence,diarrhoea) or rarely thrombocytopenia,and occasionally complications such as infection,rupture and/or haemorrhage. The preoperative diagnosis of primary splenic cysts can be ascertained by ultrasonography(USG),computed tomography or magnetic resonance imaging,although the wide use of USG today has led to an increase in the incidence of splenic cysts by 1%. However,careful histopathological evaluation along with immunostaining for presence of epithelial lining is mandatory to arrive at the diagnosis. The treatment has changed drastically from total splenectomy in the past to splenic preservation methods recently. | Sachin B Ingle Chitra R Hinge (Ingle) Swapna Patrike | 2014 | World Journal of Gastroenterology2014，20，38： | 6 |
| 4 | Crohn's disease with gastroduodenal involvement: Diagnostic approach显示文摘Crohn's disease(CD) is a chronic idiopathic inflammatory disease of gastrointestinal tract characterizedby segmental and transmural involvement of gastrointestinal tract. Ileocolonic and colonic/anorectal is a most common and account for 40% of cases and involvement of small intestine is about 30%. Isolated involvement of stomach is an extremely unusual presentation of the disease accounting for less than 0.07% of all gastrointestinal CD. To date there are only a few documented case reports of adults with isolated gastric CD and no reports in the pediatric population. The diagnosis is difficult to establish in such cases with atypical presentation. In the absence of any other source of disease and in the presence of nonspecific upper gastrointestinal endoscopy and histological findings, serological testing can play a vital role in the diagnosis of atypical CD. Recent studies have suggested that perinuclear anti-neutrophil cytoplasmic antibody and anti-Saccharomycescervisia antibody may be used as additional diagnostic tools. The effectiveness of infliximab in isolated gastric CD is limited to only a few case reports of adult patients and the long-term outcome is unknown. | Sachin B Ingle Baban D Adgaonkar Nawab P Jamadar Saleha Siddiqui Chitra R Hinge | 2015 | World Journal of Clinical Cases2015，3，6： | 5 |
| 5 | Splenic lymphoma with massive splenomegaly: Case report with review of literature显示文摘As per strict criteria of Das Gupta et al, primary splenic lymphoma is very rare. Herein, we are reporting an unusual case of primary large cell splenic lymphoma of B lineage in a middle aged female presenting with massive splenomegaly(3.8 kg) and hypersplenism. After performing therapeutic splenectomy for hypersplenism, a precise diagnosis of diffuse large B cell lymphoma was made on histopathology and confirmed by immunohistochemistry. The patient responded well to standard(Cyclophosphamide, Hydroxydaunorubicin, Oncovin(vincristine), Prednisone or prednisolone) regimen last year and is now in full remission. The splenectomy thereby has prevented the potential grave complications related to hypersplenism and splenic rupture. Our aim behind highlighting the topic is to specify that emergency splenectomy followed by anticoagulation therapy is an effective plan of management to prevent untoward complications related to disease and treatment. | Sachin B Ingle Chitra R Hinge Ingle | 2014 | World Journal of Clinical Cases2014，2，9： | 3 |
| 6 | Primary splenic lymphoma:Current diagnostic trends显示文摘The primary splenic lymphoma is extremely uncommon, can present with grave complications like hypersplenismand splenic rupture. In view of vague clinical presentation, it is difficult to arrive at the diagnosis. In such circumstances, histopathological diagnosis is very important. A precise diagnosis can only be made on histopathology and confirmed on immunohistochemistry.Emergency splenectomy is preferred as an effective therapeutic and diagnostic tool in cases with giant splenomegaly. Core biopsy is usually not advised due to a high risk of post-core biopsy complications in view of its high vascularity and fragility. Aim behind highlighting the topic is to specify that core biopsy/ fine needle aspiration cytology can be used as an effective diagnostic tool to arrive at correct diagnosis to prevent untoward complications related to disease and treatment. Anticoagulation therapy is vital after splenectomy to avoid portal splenic vein thrombosis. | Sachin B Ingle Chitra R Hinge(Ingle) | 2016 | World Journal of Clinical Cases2016，4，12： | 3 |
| 7 | Microscopic colitis: Common cause of unexplained nonbloody diarrhea显示文摘Microscopic colitis(MC) is characterized by chronic, watery, secretory diarrhea, with a normal or near normal gross appearance of the colonic mucosa. Biopsy is diagnostic and usually reveals either lymphocytic colitis or collagenous colitis. The symptoms of collagenous colitis appear most commonly in the sixth decade. Patients report watery, nonbloody diarrhea of a chronic, intermittent or chronic recurrent course. With collagenous colitis, the major microscopic characteristic is a thickened collagen layer beneath the colonic mucosa, and with lymphocytic colitis, an increased number of intraepithelial lymphocytes. Histological workup can confirm a diagnosis of MC and distinguish the two distinct histological forms, namely, collagenous and lymphocytic colitis. Presently, both forms are diagnosed and treated in the same way; thus, the description of the two forms is not of clinical value although this may change in the future. Since microscopic colitis was first described in 1976 and only recently recognized as a common cause of diarrhea, many practicing physicians may not be aware of this entity. In this review, we outline the epidemiology, risk factors associated with MC, its etiopathogenesis, the approach to diagnosis and the management of these individuals. | Sachin B Ingle Baban D Adgaonkar Chitra R Hinge(Ingle) | 2014 | World Journal of Gastrointestinal Pathophysiology2014，5，1： | 2 |
| 8 | A meta-analysis of the effects of venlafaxine on anxiety associated with depression显示文摘 | Rudolph R L Entsuah R Chitra R | 1998 | J Clin Psychopharmacol1998，18，2： | 1 |
| 9 | Effectiveness of venlafaxine treatment in a broad spectrum of depressed patients: a meta-analysis显示文摘 | Entsuah A R Rudolph R L Chitra R | 1995 | Psychopharmacol Bull1995，31，4： | 1 |
| 10 | Prediction of body weight using appropriate regression model in adult female Malabari goat 显示文摘 | Chitra R Rajendran S Prasanna D | 2012 | Veterinary World2012，5，7： | 1 |
| 11 | Hesperidin induces apoptosis and triggers autophagic markers through inhibition of Aurora-A mediated phosphoinositide-3-kinase/ Akt/mammalian target of rapamycin and glycogen synthase kinasc-3 beta signaling cascades in experimental colon carcinogenesis 显示文摘 | Saiprasad G Chitra P Manikandan R | 2014 | Eur J Cancer2014，50，14： | 1 |
| 12 | Altered Passive Eruption Complicating Opti- malOrthodontic Bracket Placement:A Case Report and Review of Lit- erature显示文摘 | Pulgaonkar R Chitra P | 2015 | J ClinDiagn Res2015，9，11： | 1 |
| 13 | Berberineattenuates bleomycin induced pulmonary toxicity and fibrosis via sup-pressing NF-kB dependant TGF-^ activation : A biphasic experimentalstudy显示文摘 | CHITRA P SAIPRASAD G MANIKANDAN R | 2013 | Toxicol Lett2013，219，2： | 1 |
| 14 | Structural properties of SnO2:F films deposited by spray pyrolysis technique 显示文摘 | AGASHE CHITRA MARATHE B R TAKWALE M G BHIDE V G | 1988 | Thin Solid Films1988，164，： | 1 |
| 15 | A meta-analysis of the effects of venlafaxine on anxiety associated with depression 显示文摘 | Rudolph RL Entsuah R Chitra R | 1998 | J Clin Psy- chopharmaeol1998，18，2： | 1 |
| 16 | Membrane application for recovery and reuse of water from treated tannery wastewater显示文摘 | Suthanthararajan R Ravindranath E Chitra K | 2004 | Desalination2004，164，2： | 1 |
| 17 | Initial clinical experience in transcatheter closure of large patent arterial ducts in infants using the modified and angled Amplatzer duct occluder 显示文摘 | Vijayalakshmi IB Chitra N Rajasri R | 2006 | Cardiol Young2006，16，4： | 1 |
| 18 | A meta-analysis of the effects of venlafaxine on anxiety associated with depression 显示文摘 | Rvedolph RL Entsuh R Chitra R | 1998 | J Clin Psychophramacol1998，18，2： | 1 |
| 19 | Amplatzer angled duct occluder for closure of patentductus arteriosus larger than the aorta in an infant显示文摘 | Vijayalakshmi IB Chitra N Rajasri R | 2005 | Pediatr Cardiol2005，26，4： | 1 |
| 20 | Mete analysis of the effects ofvenlafaxine on anxiety associated wilh depression显示文摘 | Rudolph R L Entsuah R Chitra R A | 1998 | J CIm Psychopharmacol1998，18，2： | 1 |
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