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55篇 您的检索式：作者名="Chithrani"

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	题名	作者	年代	出处	被引量
1	Elucidating the Uptake and Distribution of Nanoparticles in Solid Tumors via a Multilayered Cell Culture Model显示文摘Multicellular layers(MCLs) have previously been used to determine the pharmacokinetics of a variety of different cancer drugs including paclitaxel, doxorubicin, methotrexate, and 5-fluorouracil across a number of cell lines. It is not known how nanoparticles(NPs) navigate through the tumor microenvironment once they leave the tumor blood vessel.In this study, we used the MCL model to study the uptake and penetration dynamics of NPs. Gold nanoparticles(GNPs)were used as a model system to map the NP distribution within tissue-like structures. Our results show that NP uptake and transport are dependent on the tumor cell type. MDA-MB-231 tissue showed deeper penetration of GNPs as compared to MCF-7 one. Intracellular and extracellular distributions of NPs were mapped using Cyto Viva imaging. The ability of MCLs to mimic tumor tissue characteristics makes them a useful tool in assessing the efficacy of particle distribution in solid tumors.	Darren Yohan Charmainne Cruje Xiaofeng Lu Devika Chithrani	2015	Nano-Micro Letters2015，7，2：	3
2	Intracellular uptake, transport, and pro- cessing of gold nanostructures显示文摘	CHITHRANI D B	2010	Molecular membrane biolo- gy2010，27，7：	1
3	Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes显示文摘	Chithrani BD Chan WC	2007	Nano Lett2007，7，6：	1
4	Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells显示文摘	Chithrani BD Ghazani AA Chan WC	2006	Nano Lett2006，6，4：	1
5	Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells显示文摘	Chithrani BD Ghazani AA Chan WC	2006	Nano Lett2006，6，4：	1
6	Determining the size and shape dependence of gold nanoparticle uptake into mamma- lian cells 显示文摘	Chithrani B D Ghazani A A Chan W C	2006	Nano Letters2006，6，4：	1
7	Determi- ning the size and shape dependence of gold nanoparticle uptake into mammalian cells显示文摘	CHITHRANI B D GHAZANI A A CHAN W C	2006	Nano Letters2006，6，4：	1
8	Determi- ning the size and shape dependence of Gold nanoparticle up- take into mammalian cells显示文摘	CHITHRANI B D GHAZANI A A CHAN W C	2006	Nano Letters2006，6，4：	1
9	Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes显示文摘	CHITHRANI BD CHAN WC	2007	Nano Lett2007，7，6：	1
10	Irradia- tion of gold nanoparticles by X-rays: Monte Carlo simulation of dose enhancements and the spatial properties of the seconda- ry electrons production显示文摘	LEUNG M K CHOWJ C CHITHRANI B D	2011	Medical Physics2011，38，2：	1
11	Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanopar- ticles of different sizes and shapes显示文摘	CHITHRANI B D CHAN W C	2007	Nano Letters2007，7，6：	1
12	Determining the size and shape dependence of gold nanopartiele uptake into mammalian cells显示文摘	CHITHRANI B D GHAZANI A A CHAN W C	2006	Nano Lett2006，6，4：	1
13	Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells 显示文摘	Chithrani B D Ghazani A A Chan W C	2006	Nanomaterial Letter2006，6，：	1
14	Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes显示文摘	CHITHRANI B D CHAN W C	2007	Nano Lett2007，7，6：	1
15	Irradiation of gold nanoparti- cles by x-rays: Monte Carlo simulation of dose enhancements and the spatial properties of the secondary electrons production显示文摘	Leung MK Chow JC Chithrani BD	2011	Med Phys2011，38，2：	1
16	Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes 显示文摘	CHITHRANI B D CHANT WC	2007	Nano Letters2007，7，6：	1
17	Elucidating the mechanism of cel ular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes显示文摘	Chithrani BD Chan WC		0，，06：	1
18	Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes显示文摘	CHITHRANI B D CHAN W C W	2007	Nano Lett2007，7，6：	1
19	Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells显示文摘	CHITHRANI B D GHAZANI A A CHAN W C W	2006	Nano Lett2006，6，4：	1
20	Determi- ning the size and shape dependence of gold nanopar- ticle uptake into mammalian cells显示文摘	Chithrani BD Ghazani AA Chan WCW	2006	Nano Lett2006，6，4：	1

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