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| 1 | Surgical outcome after docetaxel-based neoadjuvant chemotherapy in locally-advanced gastric cancer显示文摘AIM:To investigate feasibility,morbidity and surgical mortality of a docetaxel-based chemotherapy regimen randomly administered before or after gastrectomy in patients suffering from locally-advanced resectable gastric cancer.METHODS:Patients suffering from locally-advanced(T3-4 any N M0 or any T N1-3 M0)gastric carcinoma,staged with endoscopic ultrasound,bone scan,computed tomography,and laparoscopy,were assigned to receive four 21 d/cycles of TCF(docetaxel 75 mg/m 2 day 1,cisplatin 75 mg/m 2 day 1,and fluorouracil 300 mg/m 2 per day for days 1-14),either before(Arm A)or after(Arm B)gastrectomy.Operative morbidity,overall mortality,and severe adverse events were compared by intention-to-treat analysis.RESULTS:From November 1999 to November 2005,70 patients were treated.After preoperative TCF(Arm A),thirty-two(94%)resections were performed,85% of which were R0.Pathological response was complete in 4 patients(11.7%),and partial in 18(55%).No surgical mortality and 28.5%morbidity rate were observed,similar to those of immediate surgery arm(P= 0.86).Serious chemotherapy adverse events tended to be more frequent in arm B(23%vs 11%,P=0.07),with a single death per arm.CONCLUSION:Surgery following docetaxel-based chemotherapy was safe and with similar morbidity to immediate surgery in patients with locally-advanced resectable gastric carcinoma. | Roberto Biffi Nicola Fazio Fabrizio Luca Antonio Chiappa Bruno Andreoni Maria Giulia Zampino Arnaud Roth Jan Christian Schuller Giancarla Fiori Franco Orsi Guido Bonomo Cristiano Crosta Olivier Huber | 2010 | World Journal of Gastroenterology2010，16，7： | 43 |
| 2 | In advanced gastric cancer:Prognosis and treatment of patients with positive peritoneal cytology显示文摘Positive peritoneal cytology in gastric cancer is classified as M1 disease by the 7thEdition of American Joint Committee on Cancer staging system.With the introduction of laparoscopy and peritoneal washing cytology in the staging of gastric cancer a new category of patients has been identified.These are patients with no macroscopic peritoneal metastases but with peritoneal cytology positive(P0C1).Prognosis and treatment of such patientsrepresent a controversial issue.We evaluate the state of the art of staging system in gastric cancer and discusss tandardisation in staging and treatment procedures.There is still a lack of uniformity in the use of laparoscopy with peritoneal cytology in clinical decision making and in the surgical treatment for gastric cancer.Survival of this patient subset remains poor.Multimodal therapies and new therapeutic strategies are required to improve the survival of these patients. | Francesco Frattini Stefano Rausei Corrado Chiappa Francesca Rovera Luigi Boni Gianlorenzo Dionigi | 2013 | World Journal of Gastrointestinal Surgery2013，5，5： | 2 |
| 3 | One stage resection and primary anast omosis following acute obstrucion of the left colon for cancer显示文摘 | Chiappa A Zbar A Biella P | 2000 | Am Surg2000，66，7： | 1 |
| 4 | Procalcitonin algorithms forantibiotic therapy decisions: a systematic review of randomizedcontrolled trials and recommendations for clinical algorithms显示文摘 | Schuetz P Chiappa V Briel M | 2011 | Arch Intern Med2011，171，15： | 1 |
| 5 | Gonadotropin-releasing hormone surge in pro-oestrous rats 显示文摘 | Sarkar D K Chiappa S A Fink G | 1976 | Nature1976，264，5585： | 1 |
| 6 | One - stage resection and primary anastomosis following acute obstruction of the left colon for cancer 显示文摘 | Chiappa A Zbar A Biella F | 2000 | Am Surg2000，66，7： | 1 |
| 7 | Inspiratory muscle training in patients with heart failure and inspiratory muscle weakness显示文摘 | Dall′Aqo P Chiappa GR Guths H | 2006 | J Am Coll Cardiol2006，47，4： | 1 |
| 8 | Thiazol- ides, a new class of anti - influenza molecules targeting viral hemagglu- tinin at the post - translational level 显示文摘 | Ossignol JF La Frazia S Chiappa L Ciucci A Santoro MG | 2009 | J Biol Chem2009，284，29： | 1 |
| 9 | Inspiratory muscle training improves blood flow to resting and exer- cising limbs in patients with chronic heart failure显示文摘 | Chiappa GR Roseguini BT Vieira PJ | 2008 | J Am Coil Cardiol2008，51，17： | 1 |
| 10 | Surgical treatment of advanced colorectal cancer in the elderly显示文摘 | Chiappa A Zbar AP Bertani E | 2005 | Chir Ital2005，57，5： | 1 |
| 11 | Neoadjuvant chemotherapy followed by hepatectomy for primarily resectable colorectal cancer liver metastases显示文摘 | Chiappa A Bertani E Makuuchi M | 2009 | Hepatogastorenterology2009，56，9192： | 1 |
| 12 | Procalcitonin algorithms for antibiotictherapy decisions : a systematic review of randomized con- trolled trials and recommendations for clinieal algorithms显示文摘 | Shuetz P Chiappa V Briel M | 2011 | Arch Intern Med2011，171，： | 1 |
| 13 | Management of breast cancer during pregnancy 显示文摘 | Rovera F Chiappa C Coglitore A | 2013 | Int J Surg2013，111，： | 1 |
| 14 | Primary and recurrent retroperitoneal soft tissue sarcoma: Prognostic factors affecting survival 显示文摘 | Chiappa A Zbar AP Bertani E | 2006 | J Surg Oncol2006，93，6： | 1 |
| 15 | Addition ofinspiratory muscle training to aerobic training improvescardiorespiratory responses to exercise in patients withheart failure and inspiratory muscle weakness 显示文摘 | Winkelmann ER Chiappa GR Lima CO | 2009 | AmHeart J2009，158，5： | 1 |
| 16 | Brainstem evoked auditory responses in 200 patients with multiple sclerosis显示文摘 | Chiappa KH Harrison JL Brooks EB | 1980 | Ann Neurol1980，7，2： | 1 |
| 17 | Management of breast cancer during pregnancy显示文摘 | Rovera F Chiappa C Coglitore A | 2013 | Int J Surg2013，11，1： | 1 |
| 18 | Inspiratory muscle training in patients with heart failure and inspiratory muscle weakness:a randomized trial显示文摘 | Chiappa G R | | 0，，04： | 1 |
| 19 | Respiratorymuscle function and exercise intolerance in heart failure显示文摘 | Ribeiro JP Chiappa GR Neder JA | 2009 | Curr Heart Fail Rep2009，6，2： | 1 |
| 20 | The Ligasure vessel sealer inliver resection: a pilot study 显示文摘 | Chiappa A Zbar AP Bertani E | 2007 | Hepatogastroenterology2007，54，80： | 1 |
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