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	题名	作者	年代	出处	被引量
1	Statistical issues and approaches in endophenotype research显示文摘The endophenotype concept was initially proposed to enhance the power of genetic studies of complex disorders. It is closely related to the genetic component in a liability-threshold model; a perfect endophenotype should have a correlation of 1 with the genetic component of the liability to disease. In reality, a putative endophenotype is unlikely to be a perfect representation of the genetic component of disease liability. The magnitude of the correlation between a putative endophenotype and the genetic component of disease liability can be estimated by fitting multivariate genetic models to twin data. A number of statistical methods have been developed for incorporating endophenotypes in genetic linkage and association analyses with the aim of improving statistical power. The most recent of such methods can handle multiple endophenotypes simultaneously for the greatest increase in power. In addition to increasing statistical power, endophenotype research plays an important role in helping to understand the mechanisms which connect the associated genetic variants with disease occurrence. Novel statistical approaches may be required for the analysis of the complex relationships between endophenotypes at different levels and how they converge to cause the occurrence of disease.	SHAM Pak Chung CHERNY Stacey S HALL Mei-Hua	2011	Chinese Science Bulletin2011，56，32：	2
2	Treatment with a copper-zinc chelator mark-edly and rapidly inhibits β-amyloid accumulation in Alzheimers disease transgenic mice显示文摘	Cherny RA Atwood CS Xilinas ME	2001	Neuron2001，30，：	1
3	Morphine and alternative opioids in cancer pain; the EAPC recommendations显示文摘	HANKS GW CONNO F CHERNY N	2001	Br J Caneer2001，84，5：	1
4	Strategiestoman-agethe adverserse effects of oral morphine an evidence-based report 显示文摘	Cherny N Ripamoti C Pereira J	2011	Journal of clinical oncology2011，19，9：	1
5	Diabetes prevalence and therapeutic target achievement in the United States, 1999 to 2006显示文摘	Cheung BM Ong KL Cherny SS	2009	Am J Med2009，122，5：	1
6	Renewable energy policy and electricity market reforms in China显示文摘	Cherni J and Kentish J	2007	Energy Policy2007，35，：	1
7	Cancer-related pain: a pan- European survey of prevalence, treatment, and patient attitudes显示文摘	Breivik H Cherny N Collett B	2009	Ann Oncol2009，20，8：	1
8	STAT3 is activated by JAK2 independent of key oncogenic driver mutations in non-small cell lung carcinoma显示文摘	Looyenga B D Hutchings D Cherni I	2012	PLoS ONE2012，7，30：	1
9	Dependence of alpha-synuclein aggregate morphology on solution conditions显示文摘	Hoyer W Antony T Cherny D	2002	J Mol Biol2002，322，2：	1
10	Characterization of the 9-cis epoxycarotenoid dioxygenase gene family and the regulation of ab- scisic acid biosynthesis in avocado显示文摘	CHERNYS J T ZEEVAART J A D	2000	Plant Physiol2000，124，1：	1
11	Opioid analgesics: comparative features and prescribing guidelines显示文摘	Cherny NI	1996	Drugs1996，51，：	1
12	Strategies for the isolation and characterization of bovine embryonic stem cells显示文摘	CHERNY R A STOKES T MoMEREI J	1994	Reprod Fertil Dev1994，6，：	1
13	Influence of Alzheimer's disease genes on cognitive decline :the Guangzhou Biobank Cohort Study 显示文摘	Gui H Jiang CQ Cherny SS	2014	Neurobiol Aging2014，35，10：	1
14	When is a moving average a semimartingal显示文摘	Cherny A	2001	MaPhySto-Research Report2001，28，：	1
15	On the uniqueness in law and the pathwise uniqueness for stochastic differential equations显示文摘	CHERNY A S	2001	Theory Probab Appl2001，46，3：	1
16	Metal oenzymelike activity of Alzheimer's disease beta-amyloid-Cu-dependent catalytic conversion of dopamine,cholesterol,and biological reducing agents to neurotoxic H2O2显示文摘	Opazo C Huang X D Cherny R A	2002	Journal of Biological Chemistry2002，277，40：	1
17	Metalloenzyme-like activity of Alzheimer's disease b-amyloid:Cu-dependent catalytic conversion of dopamine,cholesterol and biological reducing agents to neurotoxic H2O2显示文摘	Opazo C Huang X Cherny R	2002	J Biol Chem2002，277，40：	1
18	3D Modeling of Fracture Initiation From Perforated Nonce- mented Well-Bore 显示文摘	O P Alekseenko D I Potapenko S G Cherny	2013	SPE1515852013，，：	1
19	Strategies for the isolotion and characterization of borin embryonic stem cell显示文摘	CHERNY R A STOKES T M MEREI J	1994	Reprod Fort Dev1994，6，5：	1
20	Strategies to manage the adverse effects of oral morphine: an evidencebased report 显示文摘	Cherny N Ripamonti C Pereira J	2001	J Clin Oncol2001，19，9：	1

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