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| 1 | New Insights into the Depositional Environments of Ordovician Carbonate Formations in the Yubei Area of Tarim Basin Based on Standard Microfacies Types显示文摘Objective The Yubei area is located in the mid-east Maigaiti slope of southwestern Tarim Basin,China,with an exploration history of several years.Recent exploration has preliminarily indicated that the Ordovician carbonate formations in this area have some oil and gas potential.Carbonate microfacies provides material basis for reservoir development,seal formation and | HUANG Chenjun LIU Geyun MA Yongsheng LIU Bo LIU Hongguang SHI Kaibo | 2017 | Acta Geologica Sinica(English Edition)2017，91，2： | 5 |
| 2 | Effect of formulation variables on in vitro release of a water-soluble drug from chitosanesodium alginate matrix tablets显示文摘The objective of this study is to investigate the feasibility of using chitosanesodium alginate(CSeSA)based matrix tablets for extended-release of highly water-soluble drugs by changing formulation variables.Using trimetazidine hydrochloride(TH)as a water-soluble model drug,influence of dissolution medium,the amount of CSeSA,the CS:SA ratio,the type of SA,the type and amount of diluents,on in vitro drug release from CSeSA based matrix tablets were studied.Drug release kinetics and release mechanisms were elucidated.In vitro release experiments were conducted in simulated gastric fluid(SGF)followed by simulated intestinal fluid(SIF).Drug release rate decreased with the increase of CSeSA amount.CS:SA ratio had only slight effect on drug release and no influence of SA type on drug release was found.On the other hand,a large amount of water-soluble diluents could modify drug release profiles.It was found that drug release kinetics showed the best fit to Higuchi equation with Fickian diffusion as the main release mechanism.In conclusion,this study demonstrated that it is possible to design extended-release tablets of watersoluble drugs using CSeSA as the matrix by optimizing formulation components,and provide better understanding about drug release from CSeSA matrix tablets. | Liang Li Jinfeng Li Shanshan Si Linlin Wang Chenjun Shi Yujiao Sun Zhenglin Liang Shirui Mao | 2015 | Asian Journal of Pharmaceutical Sciences2015，10，4： | 2 |
| 3 | Terahertz Imaging and Spectroscopy in Cancer Diagnostics:A Technical Review显示文摘Terahertz(THz)waves are electromagnetic waves with frequency in the range from 0.1 to 10 THz.THz waves have great potential in the biomedical field,especially in cancer diagnosis,because they exhibit low ionization energy and can be used to discern most biomolecules based on their spectral fingerprints.In this paper,we review the recent progress in two applications of THz waves in cancer diagnosis:imaging and spectroscopy.THz imaging is expected to help researchers and doctors attain a direct intuitive understanding of a cancerous area.THz spectroscopy is an efficient tool for component analysis of tissue samples to identify cancer biomarkers.Additionally,the advantages and disadvantages of the developed technologies for cancer diagnosis are discussed.Furthermore,auxiliary techniques that have been used to enhance the spectral signal-to-noise ratio(SNR)are also reviewed. | Yan Peng Chenjun Shi Xu Wu Yiming Zhu Songlin Zhuang | 2020 | Biomedical Engineering Frontiers2020，1，1： | 2 |
| 4 | Hydrocarbon migration in fracture-cave systems of carbonate reservoirs under tectonic stresses: A mechanism study显示文摘The fracture-cave systems of carbonate reservoirs have almost stored 30% of recoverable oil and gasaround the world. However, it is still doubtful about the mechanism of hydrocarbon migration in thefracture-cave systems. In this work, deducing from the Eshelby’ solution, we derived the equation tocalculate the bulk strain of elliptic cylinder caves applied by stresses. Calculated results indicate that thebulk strain of caves negatively increases with the radius ratio of the elliptic cave axials under fixedstresses. In the case of the effective horizontal stress increasing from 30 MPa to 80 MPa, the bulk straindifference of a cave could be up to 0.5%. It may result in 0.4% of the total cave volume of fluid transportingthrough the fracture-cave systems within such a stress cycle. Since the tectonic stresses transform in acyclic way, the volumetric ratio of new-to-old fluid in a cave would increase with the number of stresscycles. As a result, we proposed that the periodic fluid flow induced by cyclic tectonic stresses could be animportant mechanism for hydrocarbon migration in the fracture-cave systems of carbonate reservoirs. | Chenjun Huang Geyun Liu Kaibo Shi Jinyin Yin Jinrui Guo Chongzhi Tao | 2020 | Petroleum Research2020，5，2： | 1 |
| 5 | Terahertz Spectroscopy for Accurate Identification of Panax quinquefolium Basing on Nonconjugated 24(R)-Pseudoginsenoside F_(11)显示文摘Panax quinquefolium is a perennial herbaceous plant that contains many beneficial ginsenosides with diverse pharmacological effects.24(R)-pseudoginsenoside F_(11)is specific to P.quinquefolium,a useful biomarker for distinguishing this species from other related plants.However,because of its nonconjugated property and the complexity of existing detection methods,this biomarker cannot be used as the identification standard.We herein present a stable 24(R)-pseudoginsenoside F_(11)fingerprint spectrum in the terahertz band,thereby proving that F_(11)can be detected and quantitatively analyzed via terahertz spectroscopy.We also analyzed the sample by high-performance liquid chromatography-triple quadrupole mass spectrometry.The difference between the normalized data for the two analytical methods was less than 5%.Furthermore,P.quinquefolium from different areas and other substances can be clearly distinguished based on these terahertz spectra with a standard principal component analysis.Our method is a fast,simple,and cost-effective approach for identifying and quantitatively analyzing P.quinquefolium. | Tianyi Kou Ji Ye Jing Wang Yan Peng Zefang Wang Chenjun Shi Xu Wu Xitian Hu Haihong Chen Ling Zhang Xiaohong Chen Yiming Zhu Huiliang Li Songlin Zhuang | 2021 | Plant Phenomics2021，3，1： | 1 |
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