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| 1 | Multicenter clinical study on Fuzhenghuayu capsule against liver fibrosis due to chronic hepatitis B显示文摘AIM: To study the efficacy and safety of Fuzhenghuayu capsule (FZHY capsule, a capsule for strengthening body resistance to remove blood stasis) against liver fibrosis due to chronic hepatitis B. METHODS: Multicenter, randomized, double blinded and parallel control experiment was conducted in patients (aged from 18 to 65 years) with liver fibrosis due to chronic hepatitis B. Hepatic histologic changes and HBV markers were examined at wk 0 and 24 during treatment. Serologic parameters (HA, LM, P-Ⅲ-P, Ⅳ-C) were determined and B ultrasound examination of the spleen and liver was performed at wk 0, 12 and 24. Liver function (liver function and serologic parameters for liver fibrosis) was observedat wk 0, 6, 12, 18 and 24. Blood and urine routine test, renal function and ECG were examined before and after treatment. RESULTS: There was no significant difference between experimental group (110 cases) and control group (106 cases) in demographic features, vital signs, course of illness, history for drug anaphylaxis and previous therapy, liver function, serologic parameters for liver fibrosis, liver histologic examination (99 cases in experimental group, 96 cases in control group), HBV markers, and renal function. According to the criteria for liver fibrosis staging, meanscore of fibrotic stage(s) in experimental group after treatment (1.80) decreased significantly compared to the previous treatment (2.33, P<0.05), but there was no significant difference in mean score of fibrotic stage(s) (2.11 and 2.14 respectively). There was a significant difference in reverse rate between experimental group (52%) and control group (23.3%) in liver biopsy. With marked effect on decreasing the mean value of inflammatory activity and score of inflammation (P<0.05), Fuzhenghuayu capsule had rather good effects on inhibiting inflammatory activity and was superior to that of Heluoshugan capsule. Compared to that of pretreatment, there was a significant decrease in HA, LM, P-Ⅲ-P and Ⅳ-C content in experimental group after 12 and 24 wk of treatment. The difference in HA, LM, P-Ⅲ-P and Ⅳ-C content between 12 and 24 wk of treatment and pretreatment in experimental group was significantly greater than that in control group (P<0.01-0.05). The effect, defined as two of four parameters lowering more than 30% of the baseline, was 72.7% in experimental group and 27.4% in control group (P<0.01). Obvious improvement in serum Alb, ALT, AST and GGT was seen in two groups. Compared to that of control group, marked improvement in GGT and Alb was seen in experimental group (P<0.05). The effective rate of improvement in serum ALT was 72.7% in experimental group and 59.4% in control group. No significant difference was seen in blood and urine routine and ECG before and after treatment. There was also no significant difference in stable rate in ALT and serologic parameters for liver fibrosis between experimental group and control group after 12 wk of withdrawal. CONCLUSION: Fuzhenghuayu capsule has good therapeutic effects on alleviating liver fibrosis due to chronic hepatitis B without any adverse effect and is superior to that of Heluoshugan capsule. | PingLiu Yi-YangHu ChengLiu Lie-MingXu Cheng-HaiLiu Ke-WeiSun De-ChangHu You-KuanYin xia-QiuZhou Mo-BinWan XiongCai Zhi-QingZhang JUNYe Ren-XingZhou JiaHe Bao-ZhangTang | 2005 | World Journal of Gastroenterology2005,11,19: | 60 |
| 2 | CHARACTERISTICS OF SEDIMENT TRANSPORT ALONG A RIVER REACH WITH A RESERVOIR显示文摘Based on long-term measurements at three gauging stations,Toudaoguai,Fugu and Hequ,and one meteorological station,this article discusses the features of discharge (Q) and sediment concentration (CS) of a river reach of the Yellow River with a reservoir located in the Loess Plateau. The impacts of the local sub-watershed between Toudaoguai and Fugu gauging stations on sediment budget to the Yellow River have been analyzed. In addition,the deposition processes in the Tianqiao Reservoir have been investigated. Results show over 80% of the precipitation that falls in the local sub- watershed is unable to contribute to the Yellow River runoff process. It is found that the annual maximum sediment concentration is usually less than 30 kg/m3 during flood seasons at Toudaoguai Gauging Station,but the sediment concentration varies dramatically at Fugu Gauging Station. About 35% of the sediment eroded in the sub-watersheds between Toudaoguai and Fugu gauging stations was produced from the Huangfuchuan sub-watershed which has a drainage area accounting only for 10% of the drainage area between Toudaoguai and Fugu gauging stations. The Tianqiao Reservoir generally has deposition during the summer flood season,and scouring during the non-flood season. On average,over 85% of deposited sediment in the reservoir occurs in the 12 km long lower reservoir reach. The volume of annual deposition in the reservoir mainly depends on the volume of water from the local region between Hequ and Fugu gauging stations. | JueyiSUI ChengLIU DaxianFANG JunWANG | 2005 | International Journal of Sediment Research2005,20,2: | 3 |
| 3 | A novel technique for automatic seismic data processing using both integral and local feature of seismograms显示文摘A novel technique for automatic seismic data processing using both integral and local feature of seismograms was presented in this paper.Here,the term integral feature of seismograms refers to feature which may depict the shape of the whole seismograms.However,unlike some previous efforts which completely abandon the DIAL approach,i.e.,signal detection,phase identification,association,and event localization,and seek to use envelope cross-correlation to detect seismic events directly,our technique keeps following the DIAL approach,but in addition to detect signals corresponding to individual seismic phases,it also detects continuous wave-trains and explores their feature for phase-type identification and signal association.More concrete ideas about how to define wave-trains and combine them with various detections,as well as how to measure and utilize their feature in the seismic data processing were expatiated in the paper.This approach has been applied to the routine data processing by us for years,and test results for a 16 days' period using data from the Xinjiang seismic station network were presented.The automatic processing results have fairly low false and missed event rate simultaneously,showing that the new technique has good application prospects for improvement of the automatic seismic data processing. | Ping Jin Chengliu Zhang Xufeng Shen Hongchun Wang Changzhou Pan Na Lu Xiong Xu | 2014 | Earthquake Science2014,27,3: | 3 |
| 4 | An Off-line Programming System for Flexible Drilling of Aircraft Wing Structures 显示文摘 | Zou Chengliu | 2012 | Assembly Automation2012,31,2: | 1 |
| 5 | Predictors of alpha‐fetoprotein elevation in patients with chronic hepatitis C, but not hepatocellular carcinoma, and its normalization after pegylated interferon alfa 2a–ribavirin combination therapy显示文摘 | Tsung‐MingChen Pi‐TehHuang Ming‐HungTsai Lien‐FuLin Chung‐ChengLiu Ka‐SicHo Chuan‐PauSiauw Po‐LiangChao Jai‐NienTung | 2007 | Journal of Gastroenterology and Hepatology2007,,5: | 1 |
| 6 | Predictors of alpha‐fetoprotein elevation in patients with chronic hepatitis C, but not hepatocellular carcinoma, and its normalization after pegylated interferon alfa 2a–ribavirin combination therapy显示文摘 | Tsung‐MingChen Pi‐TehHuang Ming‐HungTsai Lien‐FuLin Chung‐ChengLiu Ka‐SicHo Chuan‐PauSiauw Po‐LiangChao Jai‐NienTung | 2007 | Journal of Gastroenterology and Hepatology2007,,5: | 1 |
| 7 | Effects of tempera- ture and organic loading rate on the performance and microbial com-munity of anaerobic co - digestion of waste activated sludge and food waste显示文摘 | Gou Chengliu Yang Zhaohui Huang Jing | 2014 | Chemosphere2014,105,6: | 1 |
| 8 | Impact of phosphorus load reduction on water quality in a stratified reservoir-eutrophication modeling study 显示文摘 | Wen ChengLiu Wei BoChen Nobuaki Kimura | 2009 | Environmental Monitoring and Assessment2009,159,4: | 1 |
| 9 | Characteristics and Meteorological Conditions of Ozone Pollution in Shantou City显示文摘Based on routine monitoring data of air quality and meteorological data in Shantou City during 2015-2019,temporal-spatial variation characteristics of O 3 pollution and its correlation with meteorological conditions in Shantou City were explored.The research results showed that O 3 pollution days in Shantou City showed an increasing trend year by year,and O 3 pollution had far-distance transportation and the development trend from offshore Nan ao Island to urban district.In spring and autumn,there was serious O 3 pollution,and it was the most prominent in October.Its diurnal variation in O 3 pollution days was mainly wide-peak type in the afternoon,showing as that O 3 concentration declined slowly after the noon.In O 3 pollution days,higher O 3 concentration was easy to appear at night,causing that O 3 peak in the second day was uplifted,and there was continuous O 3 pollution.Combining backward trajectory analysis chart,it was found that Shantou was mainly affected by coastal transport of northerly polluted air mass,and it was transported into Shantou City from the east to the northeast.O 3 from long-distance transmission superimposed with locally generated O 3,which commonly pushed up the level of O 3 concentration.The weather of O 3 pollution in Shantou City had the characteristics of high temperature and low humidity.There was 25-30℃of temperature interval and 46%-60%of relative humidity interval,and it was accompanied by grade-2 easterly wind. | Juan LI Chengliu LI Lianghong XIAO Yan GUO Yiyao HUANG Shuchi CHEN Miao CHEN Wenshu LI Yufeng ZHANG | 2021 | Meteorological and Environmental Research2021,12,1: | 0 |
| 10 | Transformation Behavior and Microstructure in a 40Cr_2Ni_2MoV Cast Steel显示文摘The transformation behavior of a 40Cr2Ni2MoV cast steel manufactured by electroslag remelting (ESR) has been investigated. Compared to a forged steel, the incubation periods for both the pearlite and bainite transformations are shorter, but the transformation times are longer. The austenite is easier to transform into martensite. Optical microscopy and TEM indicated that there were variations in microstructure during the super-cooled austenite transformation. This is attributed to an inhomogeneous austenite, resulting from the segregation of elements during the ESR solidification. | ChengLiu ZhenboZhao Sanjiwan.D.Bhole DerekO.Northwood | 2004 | 材料热处理学报2004,25,5: | 0 |
| 11 | Synthesis and Characterization of Poly(ether amide)s Containing Bisphthalazinone and Ether Linkages显示文摘A novel aromatic diacid, 4, 4’-bis[2-(4-carboxyphenyl)phthalazin-1-one-4-yl]-bisphenyl ether III, containing bisphthalazinone and ether linkages was prepared from nucleophilic substitution of p-chlorobenzonitrile with the bisphenol-like monomer I, followed by alkaline hydrolysis of the intermediate dinitrile II. A series of poly(ether amide)s containing bisphthala- zinone and ether linkages derived from diacid III and aromatic diamines were synthesized by one-step solution condensation polymerization using triphenyl phosphite and pyridine as condensing agents. Moreover, the properties of poly(ether amide)s including thermal stability, solubility and crystallinity were also studied. | ChengLIU ShouHaiZHANG MingJingWANG QiZhenLIANG XiGaoJIAN | 2005 | Chinese Chemical Letters2005,16,4: | 0 |