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| 1 | Endoscopic ultrasound-guided vs endoscopic retrograde cholangiopancreatography biliary drainage for obstructed distal malignant biliary strictures: A systematic review and meta-analysis显示文摘BACKGROUND For palliation of malignant biliary obstruction(MBO), the gold-standard method of biliary drainage is endoscopic retrograde cholangiopancreatography(ERCP)with the placement of metallic stents. Endoscopic ultrasound(EUS)-guided drainage is an alternative that is typically reserved for cases of ERCP failure.Recently, however, there have been robust randomized clinical trials(RCTs)comparing EUS-guided drainage and ERCP as primary approaches to MBO.AIM To compare EUS guidance and ERCP in terms of their effectiveness and safety in palliative biliary drainage for MBO.METHODS This was a systematic review and meta-analysis, in which we searched the MEDLINE, Excerpta Medica, and Cochrane Central Register of Controlled Trials databases. Only RCTs comparing EUS and ERCP for primary drainage of MBO were eligible. All of the studies selected provided data regarding the rates of technical and clinical success, as well as the duration of the procedure, adverse events, and stent patency. We assessed the risk of biases using the Jadad score and the quality of evidence using the Grading of Recommendations Assessment,Development and Evaluation criteria.RESULTS The database searches yielded 5920 records, from which we selected 3 RCTs involving a total of 222 patients(112 submitted to EUS and 110 submitted to ERCP). In the EUS and ERCP groups, the rate of technical success was 91.96%n and 91.81%, respectively, with a risk difference(RD) of 0.00%(95%CI:-0.07, 0.07;P = 0.97; I^2 = 0%). The clinical success was 84.81% and 85.53% in the EUS and ERCP groups, respectively, with an RD of-0.01%(95%CI:-0.12, 0.10; P = 0.90; I^2 =0%). The mean difference(MD) for the duration of the procedure was-0.12%(95%CI:-8.20, 7.97; P = 0.98; I^2 = 84%). In the EUS and ERCP groups, there were14 and 25 adverse events, respectively, with an RD of-0.06%(95%CI:-0.23, 0.12; P= 0.54; I^2 = 77%). The MD for stent patency was 9.32%(95%CI:-4.53, 23.18; P =0.19; I^2 = 44%). The stent dysfunction rate was significantly lower in the EUS t group(MD =-0.22%; 95 CI:-0.35,-0.08; P = 0.001; I^2 = 0%).CONCLUSION EUS represents an interesting alternative to ERCP for MBO drainage,demonstrating lower stent dysfunction rates compared with ERCP. Technical and clinical success, duration, adverse events and patency rates were similar. | Fernanda P Logiudice Wanderlei M Bernardo Facundo Galetti Vitor M Sagae Carolina O Matsubayashi Antonio C Madruga Neto Vitor O Brunaldi Diogo T H de Moura Tomazo Franzini Spencer Cheng Sergio E Matuguma Eduardo G H de Moura | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，4： | 6 |
| 2 | Genetic transformation of wheat mediated by Agrobacterium tumefaciens显示文摘 | Cheng M Fry J E Pang S Zhou H Hironaka C M Duncan D R Conner T W Wan Y | 1997 | Plant Physiol1997，，： | 2 |
| 3 | A MyD88-dependent IFNyR-CCR2 signaling circuit is required for mobilization of monocytes and host defense against systemic bacterial challenge显示文摘 | Eric M Pietras Lloyd S Miller Carl T Johnson Ryan M O'Connell Paul W Dempsey Genhong Cheng | 2011 | Cell Research2011，21，7： | 2 |
| 4 | Telomerase activity in pleural effusions diagnostic significance显示文摘 | CHENG T Y LEE M H LAN R S | 1998 | J Clin Oncol1998，16，4： | 2 |
| 5 | Effects of the phase-separated melt on crystallization behavior and morphology in short chain branched metallocene polyethylenes显示文摘 | Fu Q Chiu F C McCreight K W Guo M Tseng W W Cheng S Z Keating M Y Hsieh E T and DesLauriers P J | | 0，，： | 2 |
| 6 | Distribution feeder reconfiguration with refined genetic algorithm显示文摘 | Lin M W Cheng F S Tsay M T | 2000 | IEE Proceedings of Generation Transmission and Distribution2000，147，6： | 2 |
| 7 | Visualization of ischaemic penumbra using a computed tomography pefusion method 显示文摘 | Cheung R T Cheng P W Lui W M | 2003 | Cerebrovasc Dis2003，15，： | 1 |
| 8 | A concise survey of scheduling with time-dependent processing times显示文摘 | Cheng T C E Ding Q Lin B M T | 2004 | European Journal of Operational Research2004，152，： | 1 |
| 9 | Characteristics, apa tire-forming ability and corrosion resistance of NiTi surface modified by AC anodization 显示文摘 | WONG M H CHENG F T MAN H C | 2007 | Appl Surface Sci2007，253，18： | 1 |
| 10 | Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion显示文摘 | SONG J SO T CHENG M | 2005 | Immunity2005，22，5： | 1 |
| 11 | Design and analysis of a new doubly salient permanent magnet motor显示文摘 | Cheng M Chau K T Chan C C | 2001 | IEEE Trans on Magnetics2001，37，4： | 1 |
| 12 | Targeting the phosphoinositide 3- kinase pathway in cancer 显示文摘 | Liu P Cheng H Roberts T M | 2009 | Nat Rev Drug Discov2009，8，8： | 1 |
| 13 | Yogurts from skim milk- whey protein concentrate blends显示文摘 | Cheng L J Augustina M A Clarke P T | 2000 | Austealian Journal of Dairy Technology2000，，55： | 1 |
| 14 | 5-fluorouracil nanopar- ticles inhibit hepatocellular carcinoma via activation of the p53 pathway in the orthotopic transplant mouse model 显示文摘 | Cheng M R He B Wan T | 2012 | PLOS ONE2012，7，47： | 1 |
| 15 | A study in Htro on differ- entiation of bone marrow mesenchymal stem cells into endometrial epi- thelial ceils in mice显示文摘 | Zhang W B Cheng M J Huang Y T | 2012 | Eur J Obstet Gynecol Reprod Binl2012，160，2： | 1 |
| 16 | Image reconstruction for bioluminescence tomography from partial measurement显示文摘 | Jiang M Zhou T Cheng 3 | 2007 | Opt Express2007，15，11： | 1 |
| 17 | Hepatoprotective effect of Phyllanthus in Taiwan on acute liver damage induced by carbon tetrachloride显示文摘 | Lee C Y Peng W H Cheng H Y Chen F N Lai M T | 2006 | The American Journal of Chinese Medicine2006，34，3： | 1 |
| 18 | Preparation and properties of nano-silica modified nega- tive acrylate photoresist 显示文摘 | Lee C K Don T M Lai W C Chert C C Lin D J Cheng L P | 2008 | Thin Solid Films2008，516，23： | 1 |
| 19 | Characterization of a virion occlusion-defective Autographa californica multiple nucleopolyhedrovirus mutant lacking the p26,p10and p74genes显示文摘 | Wang L Salem T Z Campbell D J Turney C M Kumar C M Cheng X W | 2009 | J Gen Virol2009，90，7： | 1 |
| 20 | Detectability and output feedback stabilizability of nonlinear networked control systems 显示文摘 | SAVKIN A V CHENG T M | 2007 | IEEE Transactions on Automatic Control2007，52，4： | 1 |
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