|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The relationship of Imp2 and DR3 genes with susceptibility to type Ⅰ diabetes mellitus in south China Han population显示文摘AIN To study the relationship of Imp2 and DR3genes with type Ⅰ diabetes mellitus.NETHODS Imp2 genotypes and DR3 wereidentified in 68 patients with type Ⅰ diabetesmellitus(Ⅰ-DM)and 71 healthy controls.Then,Ⅰ-DM patients and controls were respectivelyallocated into DR3-positive and DR3-negativegroups.The frequencies of Imp2 and DR3 genein random subjects,and Imp2 genotypes in DR3-matched subjects were compared between Ⅰ-DMpatients and controls.At the same time,Ⅰ-DMpatients were divided into 3 groups based on theonset age of diabetics:group A≤14 years,group B 15-30 years and group C≥31 years.RESULTS The frequency of DR3 in Ⅰ-DMpatients was significantly higher than that incontrols(47% vs 21%,P<0.005),and it wassignificantly higher in group A than that in groupB+C(70% vs 36%,x^2=7.07,P<0.01).Therewas a significant difference among groups withdifferent onset age of diabetics(x^2=8.19,rp=0.33,P<0.05).In random subjects,thefrequency of Imp2.R/R in Ⅰ-DM patients waslower(43% vs 61%,P<0.05)and Imp2.R/Hhigher(53% vs 28%,P<0.05)than that incontrols,and there was no significant differenceamong groups with different onset age ofdiabetics.In DR3-positive subjects,thefrequency of Imp2.R/R in Ⅰ-DM patients waslower(47% vs 87%,P<0.05)and Imp2-R/H higher(47% vs 13%,P<0.05)than that incontrols.In DR3-negative subjects,thefrequency of Imp2.R/H in Ⅰ-DM patients washigher than that in controls(58% vs 32%,P<0.01),but the frequency of Imp2-R/R and Imp2H/H was not significantly different betweenthese two groups.CONCLUSION DR3 gene may be one of thesusceptible genes of Ⅰ-DM,and significantlyrelated to the onset age of diabetics,and thepersons with DR3 may have an younger onsetage of diabeteS.The Imp2-R/R may be theprotective genotype of Ⅰ-DM,and Imp2-R/H thesusceptible genotype.These were not affectedby DR3 gene.Imp-2 genotypes were not relatedwith the onset age of diabetics. | Ding HL Cheng H Fu ZZ Deng QL Yan L Yan T | 2000 | World Journal of Gastroenterology2000，6，1： | 7 |
| 2 | 收缩压和舒张压变异性对脑卒中患者血管事件的不同影响显示文摘较高的血压变异性(blood pressure variability,BPV)是心血管病的危险因素。然而,在引发不同的血管事件时,收缩压变异性(systolic blood pressure variability,SBPV)和舒张压变异性(diastolic blood pressure variability,DBPV)是否存在不同作用仍不清楚。本研究旨在探讨SBPV或DBPV对急性缺血性脑卒中(acute ischaemic stroke,IS)或短暂性脑缺血发作(transient ischaemic attack,TIA)患者血管事件的作用是否存在区别。 | 周卫(译) 袁源(摘) 叶鹏(审校) Dai L Cheng A Hao X Xu J Zuo Y Wang A Meng X Li H Wang Y Zhao X Wang Y | 2020 | 中华高血压杂志2020，28，11： | 2 |
| 3 | Damage-based formability analysis for TWBs显示文摘 | Cheng C H Jie M | 2005 | International Journal of Damage Mechanics2005，14，1： | 1 |
| 4 | 显示文摘 | Wang X H Li L T | 2002 | Key Eng Mater2002，224，2： | 1 |
| 5 | Effects of supplementing with single or multiple trace minerals on growth performance,fecal mineral excretion and nutrient utilization in pullets from 1 to 18 weeks of age显示文摘 | Zhong L L Yao J H Cheng N | 2007 | Asian-Australasian Journal of Animal Science2007，20，： | 1 |
| 6 | Ent-sauchinone from Saururus chinensis 显示文摘 | Wang L H Zhao D Q Cheng D Y | 2008 | Heterocycles2008，75，5： | 1 |
| 7 | Direct observation of short-circuit diffusion during the formation of a single cupric oxide nanowire显示文摘 | Cheng C L Ma Y R Chou M H | 2007 | Nanotechnology2007，18，24： | 1 |
| 8 | Range-based sleep scheduling (RBSS) for wireless sensor networks显示文摘 | YEN L H CHENG Y M | 2009 | Wireless Personal Communications2009，48，3： | 1 |
| 9 | Feelback stabilization via designed planar centre manifold显示文摘 | DONG Y L CHENG D Z QIN H S | 2004 | International Journal of Robust and Nonlinear Control2004，14，1： | 1 |
| 10 | A test of climate, sun, and culture relationships from an 1 810 year Chinese ca- ve record显示文摘 | Zhang P Z Cheng H Edwards R L | 2008 | Science2008，322，： | 1 |
| 11 | ln-situ thermoreversible gelation of block and star copolymers of poly( ethylene glycol) and poly( N-isopropylacrylamide) of varying architectures 显示文摘 | Lin H H Cheng Y L | 2001 | Macromolecules2001，34，1： | 1 |
| 12 | Optimal trajectory syn-thesis for terrain-following flight显示文摘 | Menon P K A Kim E Cheng V H L | 1991 | Journal of Guidance Control and Dynamics1991，14，4： | 1 |
| 13 | Spinal cord repair in adult paralegic rats: Partial restoration of hind limb function 显示文摘 | Cheng H Cao Y and Olson L | 1996 | Science1996，273，： | 1 |
| 14 | Spinal cord repair in adult paraplegic rats:Partial restoration of hind limb function显示文摘 | Cheng H Cao Y Olson L | 1996 | Science1996，273，： | 1 |
| 15 | Timing, duration, and transitions of the last interglacial asian monsoon 显示文摘 | Yuan D X Cheng H Edwards R L | 2004 | Science2004，304，： | 1 |
| 16 | The holocene asian monsoon: links to solar changes and North Atlantic climate 显示文摘 | Wang Y J Cheng H Edwards R L | 2005 | Science2005，308，： | 1 |
| 17 | low-dose intraoperative mitomycin cas chemoadjuvent for pteryium surgery 显示文摘 | Cheng H C Tseng S H Kao P L | 2001 | Cornea2001，20，1： | 1 |
| 18 | The half-lives of uranium-234 and thorium-230显示文摘 | Cheng H Edwards R L Hoff J A | 2000 | Chem Geol2000，169，： | 1 |
| 19 | Circulating plasma mir-141 is a novel biomarker for metastatic colon cancer and predictspoor prognosis显示文摘 | Cheng H Zhang L Cogdell DE | 2011 | PLoS One2011，6，3： | 1 |
| 20 | Comparative study of photocatalytic performance ondifferent TiO2 nano?tubes arrays 显示文摘 | CHENG X W LIU H L CHNE Q H | 2013 | Journal of Alloysand Compounds2013，566，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员