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| 1 | Treatment of gastric varices by endoscopic sclerotherapy using butyl cyanoacrylate:10 years' experience of 635 cases显示文摘背景胃的静脉曲张( GV )为有有丁基 cyanoacrylate ( BC )的门 hypertension.Endoscopic 注射的病人是威胁生活的,为 GV 的治疗的支柱,被报导了为为它在病人的幸存上的 GV 和影响的涂去的功效仍然需要的 varices.but 放血的 hemostasis 有效我们总结了的 clarification.Here 我们 10 years'practice 到的经验从 Januar 为 GV patients.Methods 用 BC | CHENG Liu-fang WANG Zhi-qiang LI Chang-zheng CAI Feng-chun HUANG Qi-yang LINGHU En-qiang LI Wen CHAI Guo-jun SUN Guo-hui MAO Yong-ping WANG Yan-mei LI Jing GAO Ping FAN Tie-yan | 2007 | Chinese Medical Journal2007，，23： | 51 |
| 2 | Enhanced secondary pollution offset reduction of primary emissions during COVID-19 lockdown in China显示文摘To control the spread of the 2019 novel coronavirus(COVID-19),China imposed nationwide restrictions on the movement of its population(lockdown)after the Chinese New Year of 2020,leading to large reductions in economic activities and associated emissions.Despite such large decreases in primary pollution,there were nonetheless several periods of heavy haze pollution in eastern China,raising questions about the well-established relationship between human activities and air quality.Here,using comprehensive measurements and modeling,we show that the haze during the COVID lockdown was driven by enhancements of secondary pollution.In particular,large decreases in NOx emissions from transportation increased ozone and nighttime NO_(3)radical formation,and these increases in atmospheric oxidizing capacity in turn facilitated the formation of secondary particulate matter.Our results,afforded by the tragic natural experiment of the COVID-19 pandemic,indicate that haze mitigation depends upon a coordinated and balanced strategy for controlling multiple pollutants. | Xin Huang Aijun Ding Jian Gao Bo Zheng Derong Zhou Ximeng Qi Rong Tang Jiaping Wang Chuanhua Ren Wei Nie Xuguang Chi Zheng Xu Liangduo Chen Yuanyuan Li Fei Che Nini Pang Haikun Wang Dan Tong Wei Qin Wei Cheng Weijing Liu Qingyan Fu Baoxian Liu Fahe Chai Steven JDavis Qiang Zhang Kebin He | 2021 | National Science Review2021，8，2： | 47 |
| 3 | Ambient volatile organic compounds pollution in China显示文摘Owing to rapid economic and industrial development,China has been suffering from degraded air quality and visibility. Volatile organic compounds(VOCs)are important precursors to the formation of ground-level ozone and hence photochemical smog. Some VOCs adversely affect human health. Therefore,VOCs have recently elicited public concern and given new impetus to scientific interest. China is now implementing a series of polices to control VOCs pollution. The key to formulating policy is understanding the ambient VOCs pollution status. This paper mainly analyzes the species,levels,sources,and spatial distributions of VOCs in ambient air. The results show that the concentrations of ambient VOCs in China are much higher than those of developed countries such as the United States and Japan,especial benzene,which exceeds available standards. At the same time,the ozone formation potential(OFP)and secondary organic aerosol formation potential(SOAFP)of various VOCs are calculated. Aromatics and alkenes have much higher OFPs,while aromatics have higher SOAFP. The OFPs of ambient VOCs in the cities of Beijing,Guangzhou and Changchun are very high,and the SOAFP of ambient VOCs in the cities of Hangzhou,Guangzhou and Changchun are higher. | Xinmin Zhang Zhigang Xue Hong Li Li Yan Yuan Yang Yi Wang Jingchun Duan Lei Li Fahe Chai Miaomiao Cheng Weiqi Zhang | 2017 | Journal of Environmental Sciences2017，29，5： | 34 |
| 4 | Research and compilation of the Geomorphologic Atlas of the People's Republic of China (1:1,000,000)显示文摘Geomorphologic maps are one of the most fundamental materials of the natural environment. They have been widely used in scientific research,resource exploration and extraction,education and military affairs etc. An editorial committee was established in 2001 to collect materials for researching and compiling a set of new 1:1,000,000 geomorphologic atlas of China. A digital geomorphologic database was created with visual interpretation from Landsat TM/ETM imageries and SRTM-DEM etc. The atlas compiled from the database was finished. The main characteristics of the atlas are as follows:Firstly,Landsat TM/ETM imageries,published geomorphologic maps or sketches,geographical base maps,digital geological maps,and other thematic maps were collected,which were uniformly geometrically rectified,clipped into uniform sheets,and stored in the foundation database. Secondly,based on the legends of 15 sheets 1:1,000,000 maps published in the 1980s,a geomorphologic classification system was built by combining morphology and genesis types. The system comprised seven hierarchical layers:basic morphology,genesis,sub-genesis,morphology,micro-morphology,slope and aspect,material composition and lithology. These layers were stored in the database during visual image interpretation. About 2000 kinds of morpho-genesis and 300 kinds of morpho-structure were interpreted. Thirdly,the legend system was built,which included color,symbol bases and note bases etc.,compilation standards and procedures were developed,74 sheets of 1:1,000,000 covering all land and sea territories of China were compiled,the 1:1,000,000 geomorphologic atlas of the People's Republic of China was finished and published. The atlas will fill the blanks in national basic scale thematic maps,and the geomorphologic database could be applied widely in many fields in the future. | CHENG Weiming ZHOU Chenghu CHAI Huixia ZHAO Shangmin LIU Haijiang ZHOU Zengpo | 2011 | Journal of Geographical Sciences2011，21，1： | 17 |
| 5 | The Prospective Two-Dimensional Graphene Nanosheets: Preparation, Functionalization, and Applications显示文摘Graphene, as an intermediate phase between fullerene and carbon nanotube, has aroused much interests among the scientific community due to its outstanding electronic, mechanical, and thermal properties.With excellent electrical conductivity of 6000 S/cm, which is independent on chirality, graphene is a promising material for high-performance nanoelectronics, transparent conductor, as well as polymer composites. On account of its Young's Modulus of 1 TPa and ultimate strength of 130 GPa, isolated graphene sheet is considered to be among the strongest materials ever measured. Comparable with the single-walled carbon nanotube bundle,graphene has a thermal conductivity of 5000 W/(m·K), which suggests a potential application of graphene in polymer matrix for improving thermal properties of the graphene/polymer composite. Furthermore, graphene exhibits a very high surface area, up to a value of 2630 m^2/g. All of these outstanding properties suggest a wide application for this nanometer-thick, two-dimensional carbon material. This review article presents an overview of the significant advancement in graphene research: preparation, functionalization as well as the properties of graphene will be discussed. In addition, the feasibility and potential applications of graphene in areas, such as sensors, nanoelectronics and nanocomposites materials, will also be reviewed. | Zhi Yang Rungang Gao Nantao Hu Jing Chai Yingwu Cheng Liying Zhang Hao Wei Eric Siu-Wai Kong Yafei Zhang | 2012 | Nano-Micro Letters2012，4，1： | 16 |
| 6 | Management of primary small cell carcinoma of the esophagus显示文摘食管的背景主要小房间癌是稀罕的。尽管外科在根除是成功的本地肿瘤,有在切除术以后的食管的主要小房间癌的病人的五年的幸存率是比有食管的主要有鳞的房间癌的病人的低的。这研究的目的是分析 esophagus.Methods 的主要小房间癌的临床的表明,病理学的特征和治疗被外科从 1984~2003 对待的有食管的主要小房间癌的 73 个病人的一个总数被分析在这个系列的 retrospectively.Results ,全面切除术率是94.5%( 69/73 ),激进的切除术率89.0%( 65/73 )并且起作用的死亡1.4%( 1/73 )。1- ,病人的 3 年、 5 年的幸存率是 50.7% , 13.7% 和 8.2% ,食管的主要小房间癌是的 respectively.Conclusions 与差的预后稀罕。外科的切除术是为有舞台或食管的主要小房间癌的病人的领先的方法。手术后的化疗对这些病人有益。舞台的病人或应该被给化疗和放射治疗。 | SUN Ke-lin HE Jie CHENG Gui-yu CHAI Li-xun | 2007 | Chinese Medical Journal2007，，5： | 13 |
| 7 | 亚洲近视管理共识显示文摘指南的目标本指南是从国际近视研究所(IMI)白皮书中提取出来的有关近视管理方面的建议[1,2]。本指南所提供的内容都是根据现有最新数据(截至2022年3月)而来,其治疗可行性和执业范围因地区而异,应根据实际情况做调整。眼保健专家组通过对现有最优科学数据进行分析诠释,从而形成了本指南。在工作中,近视管理从业者应该将患者需求放在首位,全面考虑患者具体情况后再提出合适的处理意见。 | Monica Jong Serge Resnikoff Kah Ooi Tan 吕帆 Kah Meng Chung 胡楚南 Ian Morgan Oliver Kam Tong Woo 蓝卫忠 齐备 瞿佳 杨智宽 樊志诚 吴佩昌 Ian Flitcroft Murphy Hian Kee Chan Thok Chuan Tan Charlie Ho David Chai Wong Chong Liang Hwee Koh Olivia Qian Ru Cheng | 2022 | 中华眼视光学与视觉科学杂志2022，24，3： | 11 |
| 8 | Study on the mechanism of copper-ammonia complex decomposition in struvite formation process and enhanced ammonia and copper removal显示文摘Heavy metals and ammonia are difficult to remove from wastewater,as they easily combine into refractory complexes.The struvite formation method(SFM) was applied for the complex decomposition and simultaneous removal of heavy metal and ammonia.The results indicated that ammonia deprivation by SFM was the key factor leading to the decomposition of the copper-ammonia complex ion.Ammonia was separated from solution as crystalline struvite,and the copper mainly co-precipitated as copper hydroxide together with struvite.Hydrogen bonding and electrostatic attraction were considered to be the main surface interactions between struvite and copper hydroxide.Hydrogen bonding was concluded to be the key factor leading to the co-precipitation.In addition,incorporation of copper ions into the struvite crystal also occurred during the treatment process. | Cong Peng Liyuan Chai Chongjian Tang Xiaobo Min Yuxia Song Chengshan Duan Cheng Yu | 2017 | Journal of Environmental Sciences2017，29，1： | 9 |
| 9 | Danshen protects endothelial progenitor cells from oxidized low-density lipoprotein induced impairment显示文摘In this study,we examined the protective effects of Danshen both on endothelial progenitor cells(EPCs) in patients with hypercholesterolemia and on in-vitro EPCs of healthy volunteers.In the clinical study,we randomly divided 24 subjects with hypercholesterolemia into two groups(the control group and the Danshen-treated group).At the end of two weeks of treatment,the EPC cellular functions of both groups were tested.The results indicated that,compared to the control group,EPCs in the Danshen-treated group showed significantly better cellular functions,which was manifested in the cloning number,the proliferation capacity,the number of EPC adhesions,and cell migration.In the subsequent in-vitro experiments,EPCs were treated with vehicle,oxidized low-density lipoprotein(Ox-LDL,100 μg/ml),or Ox-LDL(100 μg/ml) plus different concentrations of Danshen(Danshensu 2,10,or 50 μg/ml,respectively) for 24 h.The results showed that Danshen treatments can prevent the detrimental effects of Ox-LDL on EPC cellular functions measured by proliferation capacity(0.24±0.08,0.37±0.11,0.30±0.04 vs.0.13±0.02,P<0.05,P<0.01,and P<0.01,respectively),and adhesion ability(63.00±11.60,70.00±10.80,85.50±11.41 vs.40.50±6.85,all P<0.01).Compared to the group treated with Ox-LDL alone,Danshen treatment significantly decreased the lipid peroxidation end product malondialdehyde(MDA) [(4.34±0.54),(3.98±0.47),(3.46±0.31) vs.(5.57±0.64) nmol/ml,all P<0.01],increased the production of superoxide dismutase(SOD) [(29.74±0.71),(31.09±0.83),(30.41±0.65) vs.(14.76±3.99) U/ml,all P<0.01],and lowered the expression of interleukin-6(IL-6) [(24.62±7.69),(27.04±3.14),(33.38±18.86) vs.(230.67±33.53) pg/ml,all P<0.01] and tumor necrosis factor-α(TNF-α) [(41.72±6.10),(17.02±6.82),(3.73±2.26) vs.(228.71±41.53) pg/ml,all P<0.01] in Ox-LDL treated EPCs.These results suggest that Danshen may exert a protective effect through its antioxidant and anti-inflammatory features. | Kang-ting JI Jun-de CHAI Cheng XING Jin-liang NAN Peng-lin YANG Ji-fei TANG | 2010 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2010，11，8： | 9 |
| 10 | Establishment of intestinal organoid cultures modeling injury-associated epithelial regeneration显示文摘The capacity of 3D organoids to mimic physiological tissue organization and functionality has provided an invaluable tool to model development and disease in vitro.However,conventional organoid cultures primarily represent the homeostasis of self-organizing stem cells and their derivatives.Here,we established a novel intestinal organoid culture system composed of 8 components,mainly including VPA,EPZ6438,LDN193189,and R-Spondin 1 conditioned medium,which mimics the gut epithelium regeneration that produces hyperplastic crypts following injury;therefore,these organoids were designated hyperplastic intestinal organoids(Hyper-organoids).Single-cell RNA sequencing identified different regenerative stem cell populations in our Hyper-organoids that shared molecular features with in vivo injury-responsive Lgr5+stem cells or Clu+revival stem cells.Further analysis revealed that VPA and EPZ6438 were indispensable for epigenome reprogramming and regeneration in Hyper-organoids,which functioned through epigenetically regulating YAP signaling.Furthermore,VPA and EPZ6438 synergistically promoted regenerative response in gut upon damage in vivo.In summary,our results demonstrated a new in vitro organoid model to study epithelial regeneration,highlighting the importance of epigenetic reprogramming that pioneers tissue repair. | Molong Qu Liang Xiong Yulin Lyu Xiannian Zhang Jie Shen Jingyang Guan Peiyuan Chai Zhongqing Lin Boyao Nie Cheng Li Jun Xu Hongkui Deng | 2021 | Cell Research2021，31，3： | 9 |
| 11 | A natural variation in Ribonuclease H-like gene underlies Rht8 to confer“Green Revolution”trait in wheat显示文摘Dear Editor,Introduction of gibberellin(GA)-insensitive Reduced height(Rht)genes,Rht-B1b and Rht-D1b,has resulted in the“Green Revolution”in modern wheat cultivars(Triticum aestivum)that has skyrocketed wheat grain yields worldwide since the 1960s(Peng et al.,1999;Velde et al.,2021).However,Rht-B1b/D1b also reduce coleoptiles,which is undesired in dryland regions where deep planting is essential for seedling establishment(Rebetzke et al.,1999,Rebetzke et al.,2001;Ellis et al.,2004). | Lingling Chai Mingming Xin Chaoqun Dong Zhaoyan Chen Huijie Zhai Junhong Zhuang Xuejiao Cheng Naijiao Wang Jia Geng Xiaobo Wang Ruolin Bian Yingyin Yao Weilong Guo Zhaorong Hu Huiru Peng Guihua Bai Qixin Sun Zhenqi Su Jie Liu Zhongfu Ni | 2022 | Molecular Plant2022，15，3： | 8 |
| 12 | H2 strain attenuated live hepatitis A vaccines:protective efficacy in a hepatitis A outbreak显示文摘AIM To investigate the protective efficacy ofH2 strain attenuated live hepatitis A vaccines(H2-strain vaccines)in hepatitis A(HA)outbreaks.METHODS With the permission of theirparents,5551 pre-school and grade 1-3 primaryschool children were inoculated with 1 dose(106.5TCID50)of H2-strain vaccines in anonrandomized,controlled trial conducted inFucheng County,Hebei Province in May 1997.Another 6485 children in the same grades andcompatible in gender and age were enrolled ascontrols.Epidemiological and serological surveywas conducted to evaluate the protectiveefficacy of the vaccines.ELISA was used todetect serum IgM anti-HAV.RESULTS HA outbreak started in early May1998,peaked in the middle of the same month,and lasted about 80 days.Overall 302 HA caseswere found,192(53.58%)were 5-9 years old.One vaccinee and 25 control cases were found tohave hepatitis A,which account for 0.28%(1/356)and 5.92%(25/422)of all vaccinees andcontrols in the 14 villages,respectively.The protective efficacy of vaccines was 95.27%(95% Cl:85.83%-104.72%).In subjects testedfor anti-HAV IgM from 13 villages,1(0.40%)overt and 11(4.06%)asymptomatic HAV caseswere found in 271 vaccinees,but 21(6.69%)ofovert and asymptomatic ones were found in 314controls.CONCLUSION H2 strain vaccines were excellent in preventing overt hepatitis A, but not so effective in preventing asymptomatic hepatitis A virus infection. A booster dose might be needed to get permanent reliable immunity. | Yu Liang Zhao Zong Da Meng Zhi Yi Xu Jun Jie Guo Shao Ai Chai Cheng Gang Duo Xuan Yi Wang Jin Feng Yao Hong Bin Liu Shun Xiang Qi Hui Bin Zhu | 2000 | World Journal of Gastroenterology2000，6，6： | 7 |
| 13 | Climate effects on an inland alpine lake in Xinjiang, China over the past 40 years显示文摘Inland lakes are important water resources in arid and semiarid regions. Understanding climate effects on these lakes is critical to accurately evaluate the dynamic changes of water resources. This study focused on the changes in Sayram Lake of Xinjiang, China, and addressed the effects of climate fluctuations on the inland lake based on long-term sequenced remote sensing images and meteorological data from the past 40 years. A geographic information system (GIS) method was used to obtain the hypsometry of the basin area of Sayram Lake, and estimation methods for evaporation from rising temperature and water levels from increasing precipitation were proposed. Results showed that: (1) Areal values of Sayram Lake have increased over the past 40 years. (2) Both temperature and precipitation have increased with average increases of more than 1.8℃ and 82 mm, respectively. Variation of the water levels in the lake was consistent with local climate changes, and the areal values show linear relationships with local temperature and precipitation data. (3) According to the hypsometry data of the basin area, the estimated lake water levels increased by 2.8 m, and the water volume increased by 12.9×10 8 m3 over the past 40 years. The increasing area of Sayram Lake correlated with local and regional climatic changes because it is hardly affected by human activities. | HuiXia CHAI WeiMing CHENG ChengHu ZHOU ShangMin ZHAO HaiJiang LIU | 2013 | Journal of Arid Land2013，5，2： | 7 |
| 14 | Formation and causes of NO_x pollution on the east side of the Taihang Mountains in China显示文摘Tropospheric column amounts of NO 2 from OMI/Aura products were applied to investigate the seasonal variation of NO x on the east side of the Taihang Mountains (ESTM) in China. The NO 2 concentration varied seasonally, with winter maxima and summer minima. To explore the causes of the heavy NO 2 pollution in this region, wind field simulations were conducted by using the Fifth-Generation NCAR/Penn State Mesoscale Model (MM5). MM5 simulations showed that wind directions in the ESTM region were dominated by northeasterly and northwesterly winds throughout the year and to a lesser degree by southwesterlies. Elevated NO 2 concentrations (higher than 50×10 15 molec/cm 2 ) occurred in three meteorological situations: convergent wind fields (5 days), northeasterly winds (2 days), and calm days (1 day) in January. Although the local anthropogenic NO x emission strength was not so high as that in other developed areas, the calms and frequent occurrence of convergent wind fields, as well as unfavorable terrains for diffusion, resulted in the accumulation of atmospheric pollutants and hence heavy NO x pollution. Furthermore, long-distance NO x transportation from the Beijing-Tianjin-Tangshan region to the ESTM area could be seen when the wind was from a northeasterly direction, especially under high wind speeds. | TIAN HeZhong WANG Yan ZHAO Dan CHAI FaHe XING ZiShan CHENG Ke | 2011 | Chinese Science Bulletin2011，56，19： | 6 |
| 15 | Shape-Controlled Synthesis of Octahedral α-NaYF_(4) and Its Rare Earth Doped Submicrometer Particles in Acetic Acid显示文摘Submicrometer sized pure cubic phase,Eu^(3+)doped,and Yb^(3+)/Er^(3+)co-dopedα-NaYF4 particles with octahedral morphology have been prepared in acetic acid.The acetate anion plays a critical role in the formation of such symmetric octahedral structures through its selective adsorption on the(111)faces of the products.The size of the as-prepared octahedra can be tuned by varying the amount of sodium acetate added to the acetic acid.A possible formation mechanism for these octahedra has been proposed.The dopedα-NaYF_(4) octahedral submicrometer particles show down-conversion and up-conversion photoluminescence typical of these materials. | Li Gao Xin Ge Zhanli Chai Guohai Xu Xin Wang Cheng Wang | 2009 | Nano Research2009，2，7： | 6 |
| 16 | Cobalt-based hydroxide nanoparticles @ N-doping carbonic frameworks core-shell structures as highly efficient bifunctional electrocatalysts for oxygen evolution and oxygen reduction reactions显示文摘高度有效、地球丰富的氧进化 / 减小反应(OER/ORR ) 的发展催化剂为可充电的金属空气电池是必要的。此处,基于钴的氢氧化物 nanoparticles @做 N 碳的框架(CoOHCat@NCF ) 核心壳结构作为高度稳定、有效的 OER/ORR bifunctional 催化剂被设计了。获得的合成表演在碱的媒介提高了催化活动和优秀稳定性。在 OER,高周转频率(在 0.36 V 的过电位的 2.03 s -1) ,在高当前的密度的低过电位(100 妈?? | Shiqiang Feng Cheng Liu Zhigang Chai Qi Li Dongsheng Xu | 2018 | Nano Research2018，11，3： | 6 |
| 17 | Straw strip mulching in a semiarid rainfed agroecosystem achieves winter wheat yields similar to those of full plastic mulching by optimizing the soil hydrothermal regime显示文摘Straw strip mulching(SM)is a new mulching technology.From 2012 to 2018,SM’s effects on soil moisture and temperature and production performances were compared with other mulching practices,using three treatments:full-cover plastic mulch(PM),no mulch with wheat sown in rows as the control(CK),and SM with 50%to 59%of the field area mulched.Compared with CK,on average over six growing seasons,SM and PM increased grain yield by 27.0%and 21.7%,straw yield by 21.6%and 22.6%,kernels ha;by 26.6%and 19.0%,net income by 29.8%and-25.0%,soil temperature at 5 cm by-1.5°C and 0.2°C from overwintering to maturity,and soil water storage at 0–200 cm by 25 and 22 mm,respectively.The increase in soil moisture in SM and PM was greater in the early period(overwintering to jointing)than in the later period(booting to maturity)and at 0 to 120 cm than at 120–200 cm in the early period.Although the mean evapotranspiration of whole growth period across six seasons was similar among treatments,SM and PM increased water consumption during the key formation period of yield components after overwintering by 16 and 32 mm,respectively,while reducing it before overwintering.Compared with CK,SM and PM had the effects of warming during overwintering and cooling after jointing.By increasing water consumption after overwintering and ratio of transpiration to evapotranspiration and providing favorable soil temperature for multiple growth stages and more sufficient soil moisture,SM and PM promoted vegetative growth and increased kernels ha^(-1),the main mechanisms by which SM and PM increased grain yield relative to CK.Relative to PM,SM is a more economically beneficial and environment-friendly technology for dryland wheat production. | Yuwei Chai Qiang Chai Rui Li Yawei Li Changgang Yang Hongbo Cheng Lei Chang Shouxi Chai | 2022 | The Crop Journal2022，10，3： | 6 |
| 18 | Geochronology,Geochemistry and Petrogenesis of Diabase Dyke Swarms in East Tianshan,Xinjiang,NW China显示文摘Diabase dyke swarms are widespread in the East Tianshan and Beishan regions. LA-ICP-MS zircon U-Pb ages of these diabase vary from 305 Ma to 278 Ma, showing that these dykes were formed during Late Carboniferous-Early Permian magmatism. All diabase samples are subalkali calc-alkali, characterized by slight LREE and LILEs enrichment, and weak negative Ti, Nb and Ta anomalies. The diabase samples have positive εNd(t) values (>+3), high Sr isotopic compositions (initial 87Sr/86Sr values=0.7030-0.7097), and large variation of Pb isotopic compositions, indicating they were derived from a deplete mantle source. Regional geology and geochemistry evidences indicate that these diabase dyke swarms were generated in a lithosphere extensional setting and had the same magma sources. Initial magmas may be a mixture of depleted asthenosphere mantle and enriched lithospheric mantle during rapid magma ascending. | ZHANG Zuoheng CHAI Fengmei WANG Tuanhua CHENG Yanbo XU Lingang YUAN Shunda | 2012 | Acta Geologica Sinica(English Edition)2012，86，6： | 5 |
| 19 | A new classification for hepatocellular carcinoma with hepatic vein tumor thrombus显示文摘Background:Hepatic vein tumor thrombus(HVTT)is a significant poor risk factor for survival outcomes in hepatocellular carcinoma(HCC)patients.Currently,the widely used international staging systems for HCC are not refined enough to evaluate prognosis for these patients.A new classification for macroscopic HVTT was established,aiming to better predict prognosis.Methods:This study included 437 consecutive HCC patients with HVTT who underwent different treatments.Overall survival(OS)and time-dependent receiver operating characteristic(ROC)curve area analysis were used to determine the prognostic capacities of the new classification when compared with the different currently used staging systems.Results:The new HVTT classification was defined as:type I,tumor thrombosis involving hepatic vein(HV),including microvascular invasion;type II,tumor thrombosis involving the retrohepatic segment of inferior vena cava;and type III,tumor thrombosis involving the supradiaphragmatic segment of inferior vena cava.The numbers(percentages)of patients with types I,II,and III HVTT in the new classification were 146(33.4%),143(32.7%),and 148(33.9%),respectively.The 1-,2-,and 3-year OS rates for types I to III HVTT were 79.5%,58.6%,and 29.1%;54.8%,23.3%,and 13.8%;and 24.0%,10.0%,and 2.1%,respectively.The time-dependent-ROC curve area analysis demonstrated that the predicting capacity of the new HVTT classification was significantly better than any other staging systems.Conclusions:A new HVTT classification was established to predict prognosis of HCC patients with HVTT who underwent different treatments.This classification was superior to,and it may serve as a supplement to,the commonly used staging systems. | Zhen-Hua Chen Kang Wang Xiu-Ping Zhang Jing-Kai Feng Zong-Tao Chai Wei-Xing Guo Jie Shi Meng-Chao Wu Wan Yee Lau Shu-Qun Cheng | 2020 | Hepatobiliary Surgery and Nutrition2020，9，6： | 5 |
| 20 | Possibilities and challenges of expanding dimensions of waterway downstream of Three Gorges Dam显示文摘The waterway in the middle and lower reaches of the Yangtze River has long been known as the Golden Waterway and has served as an important link in the construction of the Yangtze River Economic Belt.Therefore,expanding its dimensions is a significant goal,particularly given the long-range cumulative erosion occurring downstream of the Three Gorges Dam (TGD),which has been concentrated in the dry river channel.With the regulation of the volume from upstream reservoirs and the TGD,the minimum discharge and water level of the river downstream are increasing,and creating favorable conditions for the increase of the depth of the waterway.The discharge compensation effect during the dry season offsets the decline in the water level of the river channel caused by the down-cutting of part of the riverbed,but the minimum navigable water level of the segment near the dam still shows a declining trend.In recent years,several waterway remediation projects have been implemented in the downstream reaches of the TGD and although the waterway depth and width have been increased,the channel dimensions are still insufficient in the Yichang-Anqing reach (with a total length of 1026 km),as compared to the upstream reservoir area and the deep water channel in the downstream tidal reaches.A comprehensive analysis of the water depth and the number and length of shoals in the waterway indicates that its dimensions can be increased to 4.5 m ×200 m and 6.0 m×200 m in the Yichang-Wuhan and Wuhan-Anqing reaches,respectively.This is also feasible given the remediation technologies currently available,but remediation projects need to be coordinated with those for flood prevention and ecological protection. | Tao Yan Yun-ping Yang Yi-bing Li Yuan-fang Chai Xiao-bing Cheng | 2019 | Water Science and Engineering2019，12，2： | 5 |
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