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| 1 | Portal vein thrombosis in cirrhosis: Controversies and latest developments显示文摘Portal vein thrombosis(PVT) is encountered in livercirrhosis, particularly in advanced disease. It has been a feared complication of cirrhosis, attributed to significant worsening of liver disease, poorer clinical outcomes and potential inoperability at liver transplantation; also catastrophic events such as acute intestinal ischaemia. Optimal management of PVT has not yet been addressed in any consensus publication.We review current literature on PVT in cirrhosis; its prevalence, pathophysiology, diagnosis, impact on the natural history of cirrhosis and liver transplantation,and management. Studies were identified by a search strategy using MEDLINE and Google Scholar. The incidence of PVT increases with increasing severity of liver disease: less than 1% in well-compensated cirrhosis, 7.4%-16% in advanced cirrhosis. Prevalence in patients undergoing liver transplantation is 5%-16%.PVT frequently regresses instead of uniform thrombus progression. PVT is not associated with increased risk of mortality. Optimal management has not been addressed in any consensus publication. We propose areas for future research to address unresolved clinical questions. | Damian J Harding M Thamara PR Perera Frederick Chen Simon Olliff Dhiraj Tripathi | 2015 | World Journal of Gastroenterology2015，21，22： | 42 |
| 2 | Association of farnesyl diphosphate synthase polymorphisms and response to alendronate treatment in Chinese postmenopausal women with osteoporosis显示文摘 | Liu Y Li M Zhou PR Xing XP Xia WB Xu L Liu H J Zhang ZL LiaoEY Chen DC Liu J Tao TZ Wu W | 2014 | Chinese Medical Journal2014，，4： | 16 |
| 3 | Post-Mesozoic Transformation of Tectonic Domain in Southeastern China and Its Geodynamic Mechanism显示文摘Since the Mesozoic and Cenozoic, a transformation from a Tethyan Himalayan tectonic domain into a circum Pacific tectonic domain from Indosinian to Yanshanian is indicated in this paper, resulting in conspicuous changes in geophysics, tectono magmatic distribution, lithofacies and paleo geography, tectonic system in southeastern China. Tectonic analysis shows that the tectonic framework resulted from the compounding, transforming and superimposing of the two tectonic domains. The geodynamic mechanism of the transformation is mainly shown as the transverse and longitudinal heterogeneity of lithosphere, and the exchange between the crust and the mantle. | Wu Ganguo Zhang Da Faculty of Earth Sciences and Mineral Resources, China University of Geosciences, Beijing 100083, China Chen Bailin Institute of Geomechanics, CAGS, Beijing 100081, China Wu Jianshe Institute of Geological Survey of Fujian Pr | 2000 | Journal of Earth Science2000，19，3： | 12 |
| 4 | Preparation of nano-sized Bi_2Te_3 thermoelectric material powders by cryogenic grinding | Xiaozong Chen a, Leifeng Liu b, Yuan Dong a, Lianjun Wang a, Lidong Chen c, Wan Jiang a, a State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Donghua University, 2999 people of North Road, Shanghai 201620, PR China b Department of Materials and Environmental Chemistry, Stockholm University, SE-106 91 Stockholm, Sweden c Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Road, Shanghai 200050, PR China | 2012 | Progress in Natural Science:Materials International2012，22，3： | 8 |
| 5 | Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosis显示文摘Cyclin B1 是在脊椎动物控制房间周期前进的关键规章的蛋白质。Cyclin B1 绑 CDK1, cyclin 依赖的 kinase 催化子单元,形成通过关键蛋白质的磷酸化安排有丝分裂的建筑群。Cyclin B1 两个都调整 CDK1 和它的潜水艇的激活细胞的本地化,它可能为底层选择批评。这里,我们证明 cyclin B1 被专注于 kinetochore 的外部板在专业版期间中期。这本地化要求蛋白质的 cyclin 盒子区域。Cyclin B1 被微导管附件从单个 kinetochores 代替到锭子杆到 kinetochores,并且这排水量依赖于 dynein/dynactin 建筑群。由基于向量的 siRNA 的 B1 引起在 kinetochores 和微导管之间的低效的附件的 cyclin 的弄空,和染色体排列背叛,并且推迟后期的发作。在它贡献微导管的正确附件到 kinetochores 和染色体的有效排列的地方,我们断定 cyclin B1 在职业人员中期期间在 kinetochores 积累,通过由 cyclin B1-CDK1 的特定的底层的局部性的磷酸化最可能。当微导管附件被完成, Cyclin B1 然后从每 kinetochore 被搬运,并且这本地化可以重定向 cyclin B1-CDK1 的活动并且在锭子集会检查点的激活贡献。 | Chen,Q Zhang,X Jiang,Q Clarke,PR Zhang,C | 2008 | Cell Research2008，18，2： | 3 |
| 6 | RP-HPLC法测定抗栓保心片中丹参酮ⅡA的含量显示文摘 | Tan SJ Chen PR | | Chin J Chin Mater Med0，，： | 1 |
| 7 | Pandrug-resistantAcinetobacter baumannii causing nosocomial infections ina university hospital, Taiwan 显示文摘 | Hsueh PR Teng U Chen CY | 2002 | Emerg Infect Dis2002，8，8： | 1 |
| 8 | Fungal empyerna thoracis an emerging clinical entity显示文摘 | Kosc Chen KY Hsueh PR | 2000 | Chest2000，117，16： | 1 |
| 9 | Regulation of mito- chondrial respiratory chain biogenesis by estrogens/estrogen recep- tors and physiological, pathological and pharmacological implications 显示文摘 | Chen JQ Cammarata PR Baines CP | 2009 | BiochimBiophys Acta2009，1793，10： | 1 |
| 10 | A 10-year experience with bacteriology of acute thoracic empyema: emphasis on Klebsiella pneumoniae in patients with diabetes melli- tus 显示文摘 | Chen KY Hsueh PR Liaw YS | 2000 | Chest2000，117，6： | 1 |
| 11 | Pulmonary fungal infection:emphasis on microbiolgical spectra,patients outcome and prognostic factors显示文摘 | CHEN KY KO SC HSUCH PR | 2001 | Chest2001，120，1： | 1 |
| 12 | Pandrug-resistant Acinetobacter baumannii causing nosocomial infections in a u- niversity hospital Taiwan显示文摘 | Huseh PR Teng LJ Chen CY | 2002 | Emerg Infect Dis2002，8，8： | 1 |
| 13 | Outcome of oculomotor nerve palsy from posterior communicating artery aneurysms:comparison of clipping and coiling显示文摘 | Chen PR Amin-Hanjani S Albuquerque FC | 2006 | Neurosurgery2006，58，6： | 1 |
| 14 | Pandrug-resistant Acinetobacter baumannil causing nosocomial infections in a university hospital, Taiwan 显示文摘 | Hsueh PR Teng LJ Chen CY | 2002 | Emerg infect Dis2002，8，8： | 1 |
| 15 | Syphilis control among incarcerated men who have sex with men: public health response to an outbreak显示文摘 | Chen JL Callahan DB Kerndt PR | 2002 | Am J Public Health2002，92，9： | 1 |
| 16 | Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats显示文摘 | Chen J Sanberg PR Li Y | 2001 | Stroke2001，32，11： | 1 |
| 17 | Peroral pancre- atoscopy(PP) for pancreatic stone therapy and investigation of susptected pancreatic lesions: first human experience u- sing the spyglass direct visualization system (SDVS)显示文摘 | Chen YK Tarnasky PR Raijman I | 2008 | Gastrointest Endose2008，67，： | 1 |
| 18 | Aktl regulates pathological angiogenesis, vascular maturation and permeability in rive显示文摘 | Chen J Somanath PR Razorenova O | 2005 | Nat Med2005，11，11： | 1 |
| 19 | Aktl in endothe- lial cell and angiogenesis显示文摘 | Somanath PR Razorenova OV Chen J | 2006 | Cell Cycle2006，5，5： | 1 |
| 20 | Low-level laser therapy activates NF-kB via generation of reactive oxygen species in mouse embryonic fibroblasts 显示文摘 | Chen AC Arany PR Huang YY | 2011 | PLoS One2011，6，22： | 1 |
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