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| 1 | Mood swings in patients with Crohn's disease: incidence and associat ed factors显示文摘 | Lima F D Ribeiro T C Chebli L A | 2012 | Rev Assoc Med Bras2012，58，4： | 1 |
| 2 | Fracture incidence in polyostotic fibrous dysplasia and the McCune-Albright syndrome 显示文摘 | Leet AI Chebli C Kushner H | 2004 | J Bone Miner Res2004，19，4： | 1 |
| 3 | Fracture incidence in polyostotic fibrous dysplasia and the McCune-Albright syndrome显示文摘 | Leet A I Chebli C Kushner H | 2004 | J Bone Miner Res2004，19，4： | 1 |
| 4 | Fracture incidence in polyostotie fibrous dysplasia and the McCune Albright syndrome显示文摘 | Leet AI Chebli C Kushner H | 2004 | J Bone Miner Res2004，19，4： | 1 |
| 5 | Risk factors associated with inflammatory bowel disease: A multicenter case-control study in Brazil显示文摘BACKGROUND The etiology of inflammatory bowel disease(IBD)is unknown,but it is believed to be multifactorial.The hygiene hypothesis proposes that better hygiene conditions would lead to less infectious disease during childhood and favor the development of immune-mediated diseases.AIM To test the hygiene hypothesis in IBD by assessing the environmental risk factors associated with IBD development in different regions of Brazil with diverse socioeconomic development indices.METHODS A multicenter case-control study was carried out with 548 Crohn’s disease(CD)and 492 ulcerative colitis(UC)outpatients and 416 healthy controls,from six IBD centers within different Brazilian states at diverse socioeconomic development stages.A semi-structured questionnaire with 87 socioeconomic and environmental questions was applied.Logistic regression model was created to assess the odds ratio(OR)with P value and 95%confidence intervals(CI).RESULTS Predictive variables for both diseases(CD and UC)were women[odd ratios(OR)=1.31;OR=1.69],low monthly family income(OR=1.78;OR=1.57),lower number of cohabitants(OR=1.70;OR=1.60),absence of vaccination(OR=3.11;OR=2.51),previous history of bowel infections(OR=1.78;OR=1.49),and family history of IBD(OR=5.26;OR=3.33).Associated risk factors for CD were age(18-39 years)(OR=1.73),higher educational level(OR=2.22),absence of infectious childhood diseases(OR=1.99).The UC predictive variables were living in an urban area(OR=1.62),inadequate living conditions(OR=1.48)and former smokers(OR=3.36).Appendectomy was a risk factor for CD(OR=1.58)with inverse association with UC(OR=4.79).Consumption of treated and untreated water was associated with risk of CD(OR=1.38)and UC(OR=1.53),respectively.CONCLUSION This is the first examining environmental exposures as risk factors for inflammatory bowel disease in Brazil.Most of the variables associated with disease risk support the role of the hygiene hypothesis in IBD development. | Valéria Cristina Loureiro Salgado Ronir Raggio Luiz Neio Lucio Fernandes Boéchat Isabella Sued Leao Bianca do Carmo Schorr JoséMiguel Luz Parente Daniela Calado Lima Eduardo Santos Silveira Júnior Genoile Oliveira Santana Silva Neogélia Pereira Almeida Andrea Vieira Maria Luiza Queiroz de Bueno Júlio Maria Chebli érika Ruback Bertges Luísa Martins da Costa Brugnara Columbano Junqueira Neto Stefania Burjack Gabriel Campbell Luana Letiza Discacciati Joao Paulo Silva Cézar Tiago Nunes Gilaad G Kaplan Cyrla Zaltman | 2020 | World Journal of Gastroenterology2020，26，25： | 1 |
| 6 | Fracture incidence in polyostotic fibrous dysplasia and the McCune-Albright syndrome显示文摘 | Leet A I Chebli C Kushner H | 2004 | J Bone Miner Res2004，19，： | 1 |
| 7 | Characterization of gsp - mediated growth hormone excess in the context of McCune - Albright syndrome 显示文摘 | Akintoye SO Chebli C Booher S | 2002 | J Clin Endocrinol Metab2002，87，11： | 1 |
| 8 | Spontaneous bacterial peritonitis:How to deal with this life-threatening cirrhosis complication显示文摘 | Ribeiro T C Chebli J M Kondo M | 2008 | Ther Clin Risk Manag2008，4，5： | 1 |
| 9 | Fracture incidence in poly- ostotic fibrous dysplasia and the McCune - Albright syndrome 显示文摘 | Leer AI Chebli C Kushner H | 2004 | J Bone Miner Res2004，19，4： | 1 |
| 10 | Fracture incidence in polyostotic fibrous dysplasia and the McCune-Albright syndrome显示文摘 | Leet AI Chebli C Kushner H | 2004 | J Bone Miner Res2004，19，4： | 1 |
| 11 | Fracture incidence in polyos-totic fibrous dysplasia and the McCune-Albright syndrome 显示文摘 | Leet AI Chebli C Kushner H | 2004 | J Bone Miner Res2004，19，4： | 1 |
| 12 | Fracture incidence in polyostotic fibrous dysplasia and the McCune - Albright syndrome 显示文摘 | Leet AI Chebli C Kushner H | 2004 | J Bone Miner Res2004，19，： | 1 |
| 13 | Fracture incidence in polyostotic fibrous dysplasia and the McCune-Albright syndrome显示文摘 | Leet AI Chebli C Kushner H | 2004 | J Bone Miner Res2004，19，4： | 1 |
| 14 | Renal phosphate wasting in fibrous dysplasia of bone is part of a generalized renal tubular dysfunction similar to that seen in tumor induced osteomalacia显示文摘 | Collins MT Chebli C Jones J | 2001 | J Bone Miner Res2001，16，5： | 1 |
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