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| 1 | Video capsule endoscopy vs double-balloon enteroscopy in the diagnosis of small bowel bleeding:A systematic review and metaanalysis显示文摘AIM To compare the diagnostic accuracy of video capsule endoscopy(VCE) and double-balloon enteroscopy(DBE) in cases of obscure gastrointestinal bleeding(OGIB) of vascular origin.METHODS MEDLINE(via PubMed), LILACS(via BVS) and Cochrane/CENTRAL virtual databases were searched for studies dated before 2017. We identified prospective and retrospective studies, including observational, cohort, single-blinded and multicenter studies, comparing VCE and DBE for the diagnosis of OGIB, and data of all the vascular sources of bleeding were collected. All patients were subjected to the same gold standard method. Relevant data were then extracted from each included study using a standardized extraction form. We calculated study variables(sensitivity, specificity, prevalence, positive and negative predictive values and accuracy) and performed a meta-analysis using Meta-Disc software.RESULTS In the per-patient analysis, 17 studies(1477 lesions) were included. We identified3150 exams(1722 VCE and 1428 DBE) in 2043 patients and identified 2248 sources of bleeding, 1467 of which were from vascular lesions. Of these lesions, 864(58.5%) were diagnosed by VCE, and 613(41.5%) were diagnosed by DBE. The pretest probability for bleeding of vascular origin was 54.34%. The sensitivity of DBE was 84%(95%CI: 0.82-0.86; heterogeneity: 78.00%), and the specificity was92%(95%CI: 0.89-0.94; heterogeneity: 92.0%). For DBE, the positive likelihood ratio was 11.29(95%CI: 4.83-26.40; heterogeneity: 91.6%), and the negative likelihood ratio was 0.20(95%CI: 0.15-0.27; heterogeneity: 67.3%). Performing DBE after CE increased the diagnostic yield of vascular lesion by 7%, from 83% to90%.CONCLUSION The diagnostic accuracy of detecting small bowel bleeding from a vascular source is increased with the use of an isolated video capsule endoscope compared with isolated DBE. However, concomitant use increases the detection rate of the bleeding source. | Hélcio Pedrosa Brito Igor Braga Ribeiro Diogo Turiani Hourneaux de Moura Wanderley Marques Bernardo Dalton Marques Chaves Rogério Kuga Ethan Dwane Maahs Robson Kiyoshi Ishida Eduardo Turiani Hourneaux de Moura Eduardo Guimaraes Hourneaux de Moura | 2018 | World Journal of Gastrointestinal Endoscopy2018，10，12： | 10 |
| 2 | 螺内酯与可乐定作为难治性高血压第4种治疗药物的比较:难治性高血压的最佳治疗随机研究显示文摘该研究旨在通过一个多中心随机试验对作为难治性高血压患者的第4种治疗药物的螺内酯与可乐定进行比较。采用药丸计数评估药物治疗依从性。难治性高血压患者(定义为包括1种利尿剂在内的3种药物治疗12周,诊室及动态血压监测血压仍未控制)随机给予螺内酯(12.5~50 mg/d)或可乐定(0.1~0.3mg,2次/d)继续治疗12周。 | Krieger EM Drager LF Giorgi DMA Pereira AC Barreto-Filho JAS Nogueira AR Mill JG Lotufo PA Amodeo C Batista MC Bodanese LC Carvalho ACC Castro I Chaves H Costa EAS Feitosa GS Franco RJS Fuchs FD Guimarāes AC Jardim PC Machado CA Magalhāes ME Mion D Jr Nascimento RM Nobre F Nóbrega AC Ribeiro ALP Rodrigues-Sobrinho CR Sanjuliani AF Teixeira MDCB Krieger JE ReHOT Investigators 赵狄 练桂丽 | 2018 | 中华高血压杂志2018，26，3： | 7 |
| 3 | Tree allometry and improved estimation of carbon stocks and balance in tropical forests显示文摘 | Chave J Andalo C Brown S Cairns M A Chambers J Q Eamus D Folster H Fromard F Higuchi N Kira T Lescure J P Nelson B W Ogawa H Puig H Riera B Yamakura T | | 0，，： | 1 |
| 4 | Drought tolerance in relation to protection against oxidative stress in clones of Coffea canephora subjected to long-term drought显示文摘 | Pinheiro H A DaMatta F M Chaves A R M | 2004 | Plant Science2004，167，6： | 1 |
| 5 | Drought tolerance in relation to protection against oxidat'ive stress inclones of Cojfea canephora subjected to long-term drought 显示文摘 | PINHEIRO H A DAMATTA F M CHAVES ARM | 2004 | Plant Science2004，167，： | 1 |
| 6 | Predicting the risk of mobility difficulty in older women with screening nomograms: the Women's Health and Aging Study Ⅱ显示文摘 | CHAVES P H GARRETT E S FRIED L P | 2000 | Arch Intern Med2000，160，16： | 1 |
| 7 | Comparing classical community models:theoretical consequences for patterns of diversity显示文摘 | CHAVE J MULLER-LANDAU H C LEVIN S A | 2002 | The American Naturalist2002，159，1： | 1 |
| 8 | Characterization of elementary wines of Vitis vinifera varieties by pattern recognition of three amino acids profiles显示文摘 | VASCONCELLOS A M P CHAVES das NEVES H J | 1989 | Journal of Agricultural and Food Chemistry1989，37，： | 1 |
| 9 | A look at Galvanic distortion in the Tasman Sea and Juan de Fuca Plate显示文摘 | WHITE S N CHAVE A D FILLOUX J H | 1997 | Geomag Geoelectr1997，49，： | 1 |
| 10 | Can magnetic resonance imaging predict circumferential margins and TNM stage in rectal cancer显示文摘 | Branagan G Chave H Fuller C | 2004 | Dis Colon Rectum2004，47，8： | 1 |
| 11 | Impact of anemia andcardiovascular disease on frailty status of community - dwellingolder women: the Women’s Health and Aging Studies I and II显示文摘 | Chaves P H Semba R D Leng S X | 2005 | J Gerontol A BiolSci Med Sci2005，60，6： | 1 |
| 12 | An integrated indicatorbased on basin hydrology, environment, life, and poli-cy: The watershed sustainability index显示文摘 | Chaves H M L Alipaz S | 2007 | Water Re-sources Management2007，21，5： | 1 |
| 13 | Time of day at harvest affects the expremsion of chlorophyll degrading genes during postharvest storage o{ broeeoli显示文摘 | HASPERUI~ J H C~MEZ-IJOBATO M E CHAVES A R | 2013 | Postharvest Biology and Technology2013，82，： | 1 |
| 14 | Drought tolerance in relation to protection against oxidative stress in clones of Coffea eanephora subjected to long term drought显示文摘 | Pinheiro H A DaMatta F M Chaves A R M | 2004 | Plant Science2004，167，6： | 1 |
| 15 | Science requirements and the design of cabled ocean observatories 显示文摘 | Chave A D Massion G Mikada H | 2006 | Annals of Geophysics--Italy2006，49，23： | 1 |
| 16 | Can magnetic resonance imaging predict circumferential margins and TNM stage in rectal cancer? 显示文摘 | Branagan G Chave H Fuller C | 2004 | Dis Colon Rectum2004，47，8： | 1 |
| 17 | Modifica?tion of the association between ambient air pollution and lung function by frailty status among older adults in the cardiovascular health study显示文摘 | Eckel S P Louis T A Chaves P H M | 2012 | AmericanJour?nal of Epidemiology2012，176，3： | 1 |
| 18 | Drought tolerance of two field-grown clones of Coffea canephora显示文摘 | DaMatta F M Chaves A R M Pinheiro H A | 2003 | Plant Science2003，164，1： | 1 |
| 19 | Membrane transport, sensing and signaling in plant adaptation to environ- mental stress显示文摘 | CONDE A CHAVES M M GEROS H | 2011 | Plant Cell Physiol2011，52，9： | 1 |
| 20 | Membrane changes during different stages of a freeze–thaw protocol for equine semen cryopreservation显示文摘 | Deborah M Neild Bart M Gadella Mar??a Graciela Chaves Marcelo H Miragaya Ben Colenbrander Alicia Agüero | 2002 | Theriogenology2002，，8： | 1 |
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