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| 1 | Non-invasive versus invasive mechanical ventilation for respiratory failure in severe acute respiratory syndrome显示文摘Background Severe acute respiratory syndrome is frequently complicated by respiratory failure requiringventilatory support.We aimed to compare the efficacy of non-invasive ventilation against invasive mechanicalventilation treating respiratory failure in this disease.Methods Retrospective analysis was conducted on all respiratory failure patients identified from the HongKong Hospital Authority Severe Acute Respiratory Syndrome Database.Intubation rate, mortality and secondaryoutcome of a hospital utilizing non-invasive ventilation under standard infection control conditions ( NIVHospital) were compared against13 hospitals using solely invasive ventilation (IMVHospitals).Multiple logisticregression analyses with adjustments for confounding variables were performed to test for association betweenoutcomes and hospital groups.Results Both hospital groups had comparable demographics and clinical profiles, but NIV Hospital (42patients) had higher lactate dehydrogenase ratio and worse radiographic score on admission and ribavirin-corticosteroid commencement.Compared to IMV Hospitals (451 patients), NIV Hospital had lower adjustedodds ratios for intubation (0.36, 95% CI 0.164 -0.791,P=0.011) and death (0.235, 95% CI 0.077 -0.716,P=0.011), and improved earlier after pulsed steroid rescue.There were no instances of transmission ofsevere acute respiratory syndrome among health care workers due to the use of non-invasive ventilation.Conclusion Compared to invasive mechanical ventilation, non-invasive ventilation as initial ventilatory supportfor acute respiratory failure in the presence of severe acute respiratory syndrome appeared to be associated withreduced intubation need and mortality. | Loretta YC Yam Alfred YF Chan Thomas MT Cheung Eva LH Tsui Jane CK Chan Vivian CW Wong | 2005 | Chinese Medical Journal2005，，17： | 3 |
| 2 | Hepatic arteriogram for gestational trophoblastic tumor: is it useful?显示文摘 | Tam KF Chau MT Chan YM | 2005 | Cancer Investigation2005，23，8： | 1 |
| 3 | The sweet potato sporamin promoter confers high- level phytase expression and improves organic phosphorus acquisition and tuber yield of transgenic potato 显示文摘 | Hong YF Liu CY Cheng KJ Hour AL Chan MT Tseng TH Chert KY Shaw JF Yu SM | 2008 | Plant Mol Biol2008，67，： | 1 |
| 4 | BIS-guided anesthesia decreases postoperative delirium and cognitive decline显示文摘 | Chan MT Cheng BC Lee TM | 2013 | J Neurosurg Anesthesiol2013，25，1： | 1 |
| 5 | Effect of nitrous oxide anesthesia on plasma homocysteine and endothelial function显示文摘 | Myles PS Chan MT Kaye DM | 2008 | Anesthesiology2008，109，4： | 1 |
| 6 | Intravenous mag-nesium sulphate for aneurysmal subarachnoid hemorrhage(IMASH ) : a randomized,double-blinded,placebo-con-trolled ,multicenter phase III trial 显示文摘 | Wong GK Poon WS Chan MT | 2010 | Stroke2010，41，5： | 1 |
| 7 | BIS-guided anesthesia decreases postoperative delirium and cognitive decline 显示文摘 | Chan MT Cheng BC Lee TM | 2013 | JNeurosurg Anesthesiol2013，25，1： | 1 |
| 8 | BIS-guided Anesthe- sia Decreases Postoperative Delirium and Cognitive Decline 显示文摘 | CHAN MT CHENG BC LEE TM | 2013 | Neurosurg Anesthesiol2013，25，1： | 1 |
| 9 | Intravenous magnesium sulfate after aneurysmal subarachnoid hemorrhage:a prospective randomized pilot study显示文摘 | Wong GK Chan MT Boet R | 2006 | J Neurosurg Anesthesiol2006，18，2： | 1 |
| 10 | Noninvasive positive-pressure ventilation: an experimental model to assess air and particle dispersion显示文摘 | Hui DS Hall SD Chan MT | 2006 | Chest2006，130，： | 1 |
| 11 | Priming abiotic factors for optimal hybrid Cymbidium (Orchidaceae) PLB and callus induction, plantlet formation, and their subsequent cytogenetic stability analysis显示文摘 | Jaime A Teixeira DS Chan MT | 2006 | Scientia Horticulturae2006，109，： | 1 |
| 12 | Co-digestion of swine manure and corn stover for bioenergy production in MixAlco consolidated bioprocessing显示文摘 | Chan WN Fu ZH Holtzapple MT | 2011 | Biomass and Bioenergy2011，35，： | 1 |
| 13 | Structured preoperative patient education for patient-controlled analgesia显示文摘 | Lam KK Chan MT Chen PP | 2001 | J Clin Anesth2001，13，6： | 1 |
| 14 | Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery 显示文摘 | Devereaux PJ Chan MT Alonse-CocUo P eta/ | 2012 | Jama2012，307，21： | 1 |
| 15 | Agrobacterium-mediated production of transgenic rice plants expressing a chimeric α~amylase promoter/β-glucuronidase gene显示文摘 | Chang HH Ho SL | 1993 | Plant Mol Biol1993，22，： | 1 |
| 16 | Intravenous magnesium sulfate after aneurysmal subarachnoid hemorrhage : a prospective randomized pilot study 显示文摘 | Wong GK Chan MT Boet R | 2006 | J Neurosurg Anesthesiol2006，18，2： | 1 |
| 17 | Outcome in patients at high risk after open surgical repair of abdominal aortic aneurysm 显示文摘 | Menard MT Chew DK Chan RK | 2003 | J Vase Surg2003，37，2： | 1 |
| 18 | Re-defining the ischemic threshold for jugular oxygen saturation-a microdialysis study in patients with severe head injury显示文摘 | Chan MT Ng SC Lam JM | 2005 | Acta Neurochir Suppl2005，95，： | 1 |
| 19 | BIS-guided anesthe- sia decreases postoperative delirium and cognitive decline 显示文摘 | Chan MT Cheng BC Lee TM | 2013 | J Neurosurg Anesthesiol2013，25，1： | 1 |
| 20 | Nrf2-deficient mice have an increased susceptibility to dextran sulfate sodiuminduced colitis显示文摘 | Khor TO Huang MT Kwon KH Chan JY Reddy BS Kong AN | 2006 | Cancer Res2006，66，11： | 1 |
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