| 9 | Clinical challenge for gastroenterologists–Gastrointestinal manifestations of systemic mastocytosis:A comprehensive review显示文摘Mastocytosis is a rare and heterogeneous disease characterized by various clinical and biological features that affect different prognoses and treatments.The disease is usually divided into 2 principal categories:cutaneous and systemic disease(SM).Clinical features can be related to mast cell(MC)mediator release or pathological MC infiltration.SM is a disease often hard to identify,and the diagnosis is based on clinical,biological,histological,and molecular criteria with different specialists involved in the patient’s clinical work-up.Among all manifestations of the disease,gastrointestinal(GI)symptoms are common,being present in 14%-85% of patients,and can significantly impair the quality of life.Here we review the data regarding GI involvement in SM,in terms of clinical presentations,histological and endoscopic features,the pathogenesis of GI symptoms,and their treatment. | Alessandra Elvevi Elena Maria Elli Martina Luca Miki Scaravaglio Fabio Pagni Stefano Ceola Laura Ratti Pietro Invernizzi Sara Massironi | 2022 | World Journal of Gastroenterology2022，28，29： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员