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| 1 | Helicobacter pylori infection and drugs malabsorption显示文摘Drug absorption represents an important factor affecting the efficacy of oral drug treatment.Gastric secretion and motility seem to be critical for drug absorption.A causal relationship between impaired absorption of orally administered drugs and Helicobacter pylori(H.pylori)infection has been proposed.Associations have been reported between poor bioavailability of l-thyroxine and l-dopa and H.pylori infection.According to the Maastricht Florence Consensus Report on the management of H.pylori infection,H.pylori treatment improves the bioavailability of both these drugs,whereas the direct clinical benefits to patients still await to be established.Less strong seems the association between H.pylori infection and other drugs malabsorption,such as delavirdine and ketoconazole.The exact mechanisms forming the basis of the relationship between H.pylori infection and impaired drugs absorption and/or bioavailability are not fully elucidated.H.pylori infection may trigger a chronic inflammation of the gastric mucosa,and impaired gastric acid secretion often follows.The reduction of acid secretion closely relates with the wideness and the severity of the damage and may affect drug absorption.This minireview focuses on the evidence of H.pylori infection associated with impaired drug absorption. | Edith Lahner Camilla Virili Maria Giulia Santaguida Bruno Annibale Marco Centanni | 2014 | World Journal of Gastroenterology2014，20，30： | 6 |
| 2 | Artifi cial neural networks in the recognition of the presence of thyroid disease in patients with atrophic body gastritis显示文摘AIM: To investigate the role of artifi cial neural networks in predicting the presence of thyroid disease in atrophic body gastritis patients. METHODS: A dataset of 29 input variables of 253 atrophic body gastritis patients was applied to artifi cial neural networks (ANNs) using a data optimisation procedure (standard ANNs,T&T-IS protocol,TWIST protocol). The target variable was the presence of thyroid disease. RESULTS: Standard ANNs obtained a mean accuracy of 64.4% with a sensitivity of 69% and a specifi city of 59.8% in recognizing atrophic body gastritis patients with thyroid disease. The optimization procedures (T&T-IS and TWIST protocol) improved the performance of the recognition task yielding a mean accuracy,sensitivity and specifi city of 74.7% and 75.8%,78.8% and 81.8%,and 70.5% and 69.9%,respectively. The increase of sensitivity of the TWIST protocol was statistically signifi cant compared to T&T-IS. CONCLUSION: This study suggests that artificial neural networks may be taken into consideration as a potential clinical decision-support tool for identifying ABG patients at risk for harbouring an unknown thyroid disease and thus requiring diagnostic work-up of their thyroid status. | Edith Lahner Marco Intraligi Massimo Buscema Marco Centanni Lucy Vannella Enzo Grossi Bruno Annibale | 2008 | World Journal of Gastroenterology2008，14，4： | 6 |
| 3 | A dose-ranging study of indacaterol in obstructive airways disease, with a tiotropium comprison 显示文摘 | Rennard S Bantje T Centanni S | 2008 | Respir Med2008，102，7： | 1 |
| 4 | Parathyroid reimplanta- tion in forearm subcutaneous tissue during thyroideetomy : A simple and efeetive way to avoid hypoparathyroidism显示文摘 | Cavallaro G Iorio O Centanni M | 2015 | World J Surg2015，39，8： | 1 |
| 5 | Psychological issues in treat- ment of asthmatic patients 显示文摘 | Centanni S MarcO FD Castagna F | 2000 | Respir Med2000，94，8： | 1 |
| 6 | Psychological issues in the treatment of asthmatic patients显示文摘 | Centanni S Di Marco F Castagna F | | 0，，： | 1 |
| 7 | Increased plasma level ofendothelin-1 in patients with hyperthyroidism 显示文摘 | Letizia C Centanni M Cesareo R | 1995 | Metabolism1995，44，10： | 1 |
| 8 | Onset of action of single doses of formoterol administered via Turbuhaler in patients with stable COPD 显示文摘 | Cazzola M Centanni S Regorda C | 2001 | Pulmonary Pharmacolog Therapoutics2001，14，1： | 1 |
| 9 | Psychological issues in the treatment of asthmatic patients显示文摘 | Centanni S Di Marco F Castagna F | 2000 | Respir Med2000，94，8： | 1 |
| 10 | Imposex and accumulation of organotin compounds in populations of Hexaplex trunculus (Gastropoda, Muricidae ) from the Lagoon of Venice (Italy) and Istrian Coast (Croatia) 显示文摘 | Garaventa F Centanni E Pellizzato F | 2007 | Mar Poilu Bull2007，54，5： | 1 |
| 11 | Thyroxine in goiter, Helicobacter pylori infection,and chronic gastritis 显示文摘 | Centanni M Gmgano Canettieri G | 2006 | N Engl J Med2006，354，17： | 1 |
| 12 | Comparison of the bronchodi- lating effect of salmeterol and zafirlukast in combination with that of their use as single treatment in asthma and chronic obstructive pulmonary disease 显示文摘 | Cazzola M Centanni S Boveri B | 2001 | Respiration2001，68，： | 1 |
| 13 | 显示文摘 | Centanni M Cesareo R Verall O | 1997 | Eur J Endocrinol1997，136，6： | 1 |
| 14 | Anxiety and depression in asthma 显示文摘 | Di Marco F ' Santus P Centanni S | 2011 | Curr Opin Pulm Med2011，17，1： | 1 |
| 15 | Bronehodilating effect of oxitropium bromide in heart disease patients with exacerbations of COPD:double - blind, randomized, controlled study 显示文摘 | Centanni S Santus P | 2002 | Respir Med2002，96，3： | 1 |
| 16 | Advances in the research and development of chemotherapeutic agents for respiratory tract bacterial infections显示文摘 | Cazzola M Blasi F Centanni S | 2001 | Pulm Pharmacol Ther2001，14，5： | 1 |
| 17 | Immunocytochemical expression of Ki67 and laminin in Hurthle cell adenomas and carcinomas显示文摘 | Pisani T Pantellini F Centanni M | 2003 | Anticancer Res2003，23，4： | 1 |
| 18 | Acute exacerbation of asth ma in adult s:role of Chlamydia pneumoniae infection显示文摘 | Allegra L Blasi F Centannis S | 1994 | Eur Respir J1994，7，12： | 1 |
| 19 | Advances in the research and development of chemotherapeutic agents for respiratory tract bacterial infections 显示文摘 | Cazzola M Blasi F Centanni S | 2001 | Pulm Pharmacol Ther2001，14，5： | 1 |
| 20 | Optimization of ventilator setting by flow and pressure waveforms analysis during noninvasive Ventilation for acute exacerbations of COPD: a multicentric randomized controlled trial显示文摘 | Di Marco F Centanni S Bellone A | 2011 | Crit Care2011，15，6： | 1 |
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