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| 1 | Effects of testosterone and estradiol on anxiety and depressive-like behavior via a non-genomic pathway显示文摘Besides their known slow genomic effects, testosterone and estradiol have rapid effects in the brain. However, their impact on mood-related behavior is not clear. The aim of this study was to investigate the non-genomic pathway of testosterone and estradiol in the amygdala in relation to anxiety and depressive-like behavior. Sham-operated and gonadectomized male rats(GDX) supplemented with testosterone propionate, estradiol, or olive oil were used. Five minutes after administration, anxiety and depression-like behavior were tested. Estradiol increased anxiolytic behavior in the open-field test compared to the GDX group, but administration of testosterone had no significant effect. Besides, c-Fos expression in the medial nucleus of the amygdala significantly increased after testosterone treatment compared to the GDX group, while no significant difference was observed in the central and the basolateral nuclei of the amygdala in the testosterone-treated group compared to the GDX group. In conclusion, estradiol had an anxiolytic effect via a rapid pathway, but no rapid effect of testosterone on anxiety was found. Further studies elucidating whether the rapid effect is mediated by a non-genomic pathway are needed. | Barbora Filova Maria Malinova Janka Babickova Lubomira Tothova Daniela Ostatnikova Peter Celec Julius Hodosy | 2015 | Neuroscience Bulletin2015，31，3： | 3 |
| 2 | Nuclear factor kappa B - - molecular biomedicine : the next generation 显示文摘 | Celec P | 2004 | Biomed Pharmacother2004，58，67： | 1 |
| 3 | Sleep apnea syndrome and its complica- tions显示文摘 | Jurkovicova I Celec P | 2004 | Acta Med Austriaea2004，31，2： | 1 |
| 4 | Targeting angiogenesis for cancer (gene) therapy显示文摘 | Gardlik R Celec P Bernadic M | 2011 | Bratisl Lek Listy2011，112，8： | 1 |
| 5 | Oxidative stress and electron spin resonance显示文摘 | Kopani M Celec P Danisovic L | | 0，，1： | 1 |
| 6 | Nuclear factor kappa B- molecular biomedicine: the next generation 显示文摘 | Celec P | 2005 | Biomedcine Phamacotherapy2005，58，67： | 1 |
| 7 | Antioxidant vitamins prevent oxidative and carbonyl stress in an animal model of obstructive sleep apnea 显示文摘 | Celec P Jurkovicova I Buchta R | 2013 | Sleep Breath2013，17，： | 1 |
| 8 | Nuclear factor kappa B-molecular biomedicine: the next generation显示文摘 | Celec P | 2004 | Biomed Pharmacother2004，58，67： | 1 |
| 9 | Vascular endothelial growth factor-basic science and its clinical implications 显示文摘 | Celec P Yonemitsu Y | 2004 | Pathophysiology2004，11，2： | 1 |
| 10 | Nuclear factor kappa B-molecular biomedicine:the next generation显示文摘 | Celec P | 2004 | Biomed Pharmacother2004，58，67： | 1 |
| 11 | A systematic review of randomized con- trolled trials using music therapy for children显示文摘 | Mrazova M Celec P | 2010 | J Altern Complement Med2010，16，10： | 1 |
| 12 | Fragmentation of DNA affects the accuracy of the DNA quantitation by the commonly usedmethods显示文摘 | Sedlackova T Repiska G Celec P | 2013 | Bioi Proced Online2013，15，1： | 1 |
| 13 | Sleep apnea syndrome and its complica- tions显示文摘 | Jurkovieova I Celec P | 2004 | Acta Med Austriaca2004，31，2： | 1 |
| 14 | Sleep apnea syndrome and its complications显示文摘 | Jurkovicova I Celec P | 2004 | Acta Med Austriaca2004，31，2： | 1 |
| 15 | The use of transformed Escherichia coli for experimental angiogenesis induced by regulated in situ production of vascular endothelial growth factor-an alternative gene therapy 显示文摘 | Celec P Gardlik R Prlffy R | 2005 | Med Hypotheses2005，64，： | 1 |
| 16 | Effects of bacteria?mediated reprogramming and antibiotic pretreatmenton the course of colitis in mice显示文摘 | Roman Gardlik Alexandra Wagnerova Peter Celec | 2014 | Molecular Medicine Reports2014，，2： | 1 |
| 17 | Sleep apnea syndrome and its complications 显示文摘 | Jurkovicova I Celec P | 2004 | Acta Med Austriaea2004，31，2： | 1 |
| 18 | Vascular endothelial growth factor targeted RNA interference as a modulator of angiogenesis显示文摘 | Celec P Yonemitsu Y | 2008 | Biomed Phar- macother2008，62，6： | 1 |
| 19 | Therapeutic DNA vaccination and RNA interference in inflammatory boweldisease显示文摘 | Roman Gardlik Anastazie Bartonova Peter Celec | 2013 | International Journal of Molecular Medicine2013，，2： | 1 |
| 20 | Nuclear factor kappa B--molecular biomedicine:the next generation显示文摘 | CELEC P | 2004 | Biomed Pharmacother2004，58，67： | 1 |
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